Cancer patient survival can be parametrized to improve trial precision and reveal time-dependent therapeutic effects

por Plana, Deborah, Fell, Geoffrey, Alexander, Brian M., Palmer, Adam C., Sorger, Peter K.
Publicado 2022

The effects of releasing early results from ongoing clinical trials

por Ventz, Steffen, Bacallado, Sergio, Rahman, Rifaquat, Tolaney, Sara, Schoenfeld, Jonathan D., Alexander, Brian M., Trippa, Lorenzo
Publicado 2021

Evidence‐Based Development and Clinical Use of Precision Oncology Therapeutics

por Comment, Leah A., Ward, Ashley F., Schrock, Alexa B., Fabrizio, David, Venstrom, Jeffrey M., Hegde, Priti S., Alexander, Brian M.
Publicado 2020

Prevalence of High-Risk Nonvaccine Human Papillomavirus Types in Advanced Squamous Cell Carcinoma Among Individuals of African vs Non-African Ancestry

por Williams, Erik A., Newberg, Justin, Williams, Kevin Jon, Montesion, Meagan, Alexander, Brian M., Lin, Douglas I., Elvin, Julia A.
Publicado 2021

A quantitative framework for modeling COVID-19 risk during adjuvant therapy using published randomized trials of glioblastoma in the elderly

por Tabrizi, Shervin, Trippa, Lorenzo, Cagney, Daniel, Tanguturi, Shyam, Ventz, Steffen, Fell, Geoffrey, Wen, Patrick Y, Alexander, Brian M, Rahman, Rifaquat
Publicado 2020

The design and evaluation of hybrid controlled trials that leverage external data and randomization

por Ventz, Steffen, Khozin, Sean, Louv, Bill, Sands, Jacob, Wen, Patrick Y., Rahman, Rifaquat, Comment, Leah, Alexander, Brian M., Trippa, Lorenzo
Publicado 2022

Ipilmumab and cranial radiation in metastatic melanoma patients: a case series and review

por Schoenfeld, Jonathan D., Mahadevan, Anand, Floyd, Scott R., Dyer, Michael A., Catalano, Paul J., Alexander, Brian M., McDermott, David F., Kaplan, Irving D.
Publicado 2015

KMDATA: a curated database of reconstructed individual patient-level data from 153 oncology clinical trials

por Fell, Geoffrey, Redd, Robert A, Vanderbeek, Alyssa M, Rahman, Rifaquat, Louv, Bill, McDunn, Jon, Arfè, Andrea, Alexander, Brian M, Ventz, Steffen, Trippa, Lorenzo
Publicado 2021

The impact of different stereotactic radiation therapy regimens for brain metastases on local control and toxicity

por Jimenez, Rachel B., Alexander, Brian M., Mahadevan, Anand, Niemierko, Andrzej, Rajakesari, Selvan, Arvold, Nils D., Floyd, Scott R., Oh, Kevin S., Loeffler, Jay S., Shih, Helen A.
Publicado 2017

Somatic mutations associated with MRI-derived volumetric features in glioblastoma

por Gutman, David A., Dunn, William D., Grossmann, Patrick, Cooper, Lee A. D., Holder, Chad A., Ligon, Keith L., Alexander, Brian M., Aerts, Hugo J. W. L.
Publicado 2015

Prevalence of High Tumor Mutational Burden and Association With Survival in Patients With Less Common Solid Tumors

por Shao, Changxia, Li, Gerald, Huang, Lingkang, Pruitt, Scott, Castellanos, Emily, Frampton, Garrett, Carson, Kenneth R., Snow, Tamara, Singal, Gaurav, Fabrizio, David, Alexander, Brian M., Jin, Fan, Zhou, Wei
Publicado 2020

Characterization of Non–Small-Cell Lung Cancers With MET Exon 14 Skipping Alterations Detected in Tissue or Liquid: Clinicogenomics and Real-World Treatment Patterns

por Lee, Jessica K., Madison, Russell, Classon, Anthony, Gjoerup, Ole, Rosenzweig, Mark, Frampton, Garrett M., Alexander, Brian M., Oxnard, Geoffrey R., Venstrom, Jeffrey M., Awad, Mark M., Schrock, Alexa B.
Publicado 2021

CYLD mutation characterizes a subset of HPV-positive head and neck squamous cell carcinomas with distinctive genomics and frequent cylindroma-like histologic features

por Williams, Erik A., Montesion, Meagan, Alexander, Brian M., Ramkissoon, Shakti H., Elvin, Julia A., Ross, Jeffrey S., Williams, Kevin Jon, Glomski, Krzysztof, Bledsoe, Jacob R., Tse, Julie Y., Mochel, Mark C.
Publicado 2020

Melanomas with activating RAF1 fusions: clinical, histopathologic, and molecular profiles

por Williams, Erik A., Shah, Nikunj, Montesion, Meagan, Sharaf, Radwa, Pavlick, Dean C., Sokol, Ethan S., Alexander, Brian M., Venstrom, Jeff M., Elvin, Julia A., Ross, Jeffrey S., Tse, Julie Y., Mochel, Mark C.
Publicado 2020

Assessment of Simulated SARS-CoV-2 Infection and Mortality Risk Associated With Radiation Therapy Among Patients in 8 Randomized Clinical Trials

por Tabrizi, Shervin, Trippa, Lorenzo, Cagney, Daniel, Aizer, Ayal A., Tanguturi, Shyam, Ventz, Steffen, Fell, Geoffrey, Bellon, Jennifer R., Mamon, Harvey, Nguyen, Paul L., D’Amico, Anthony V., Haas-Kogan, Daphne, Alexander, Brian M., Rahman, Rifaquat
Publicado 2021

The role of whole brain radiation therapy in the management of melanoma brain metastases

por Dyer, Michael A, Arvold, Nils D, Chen, Yu-Hui, Pinnell, Nancy E, Mitin, Timur, Lee, Eudocia Q, Hodi, F Stephen, Ibrahim, Nageatte, Weiss, Stephanie E, Kelly, Paul J, Floyd, Scott R, Mahadevan, Anand, Alexander, Brian M
Publicado 2014

Distinct genomic subclasses of high-grade/progressive meningiomas: NF2-associated, NF2-exclusive, and NF2-agnostic

por Williams, Erik A., Santagata, Sandro, Wakimoto, Hiroaki, Shankar, Ganesh M., Barker, Fred G., Sharaf, Radwa, Reddy, Abhinav, Spear, Phoebe, Alexander, Brian M., Ross, Jeffrey S., Brastianos, Priscilla K., Cahill, Daniel P., Ramkissoon, Shakti H., Juratli, Tareq A.
Publicado 2020

FoundationOne CDx testing accurately determines whole arm 1p19q codeletion status in gliomas

por Sharaf, Radwa, Pavlick, Dean C, Frampton, Garrett M, Cooper, Maureen, Jenkins, Jacqueline, Danziger, Natalie, Haberberger, James, Alexander, Brian M, Cloughesy, Timothy, Yong, William H, Liau, Linda M, Nghiemphu, Phioanh L, Ji, Matthew, Lai, Albert, Ramkissoon, Shakti H, Albacker, Lee A
Publicado 2021

Erratum to: FoundationOne CDx testing accurately determines whole arm 1p19q codeletion status in gliomas

por Sharaf, Radwa, Pavlick, Dean C, Frampton, Garrett M, Cooper, Maureen, Jenkins, Jacqueline, Danziger, Natalie, Haberberger, James, Alexander, Brian M, Cloughesy, Timothy, Yong, William H, Liau, Linda M, Nghiemphu, Phioanh L, Ji, Matthew, Lai, Albert, Ramkissoon, Shakti H, Albacker, Lee A
Publicado 2021

Genomic Profiling of Combined Hepatocellular Cholangiocarcinoma Reveals Genomics Similar to Either Hepatocellular Carcinoma or Cholangiocarcinoma

por Murugesan, Karthikeyan, Sharaf, Radwa, Montesion, Meagan, Moore, Jay A., Pao, James, Pavlick, Dean C., Frampton, Garrett M., Upadhyay, Vivek A., Alexander, Brian M., Miller, Vincent A., Javle, Milind M., Bekaii Saab, Tanios S., Albacker, Lee A., Ross, Jeffrey S., Ali, Siraj M.
Publicado 2021