Haematopoietic stem cells: past, present and future

por Ng, Ashley P, Alexander, Warren S
Publicado 2017

SOCS-1 regulates IL-15–driven homeostatic proliferation of antigen-naive CD8 T cells, limiting their autoimmune potential

por Davey, Gayle M., Starr, Robyn, Cornish, Ann L., Burghardt, J. Theodore, Alexander, Warren S., Carbone, Francis R., Surh, Charles D., Heath, William R.
Publicado 2005

Rapid Inflammation in Mice Lacking Both SOCS1 and SOCS3 in Hematopoietic Cells

por Ushiki, Takashi, Huntington, Nicholas D., Glaser, Stefan P., Kiu, Hiu, Georgiou, Angela, Zhang, Jian-Guo, Metcalf, Donald, Nicola, Nicos A., Roberts, Andrew W., Alexander, Warren S.
Publicado 2016

The BH3-only proteins BIM and PUMA are not critical for the reticulocyte apoptosis caused by loss of the pro-survival protein BCL-XL

por Delbridge, Alex RD, Aubrey, Brandon J, Hyland, Craig, Bernardini, Jonathan P, Di Rago, Ladina, Garnier, Jean-Marc, Lessene, Guillaume, Strasser, Andreas, Alexander, Warren S, Grabow, Stephanie
Publicado 2017

The necroptotic cell death pathway operates in megakaryocytes, but not in platelet synthesis

por Moujalled, Diane, Gangatirkar, Pradnya, Kauppi, Maria, Corbin, Jason, Lebois, Marion, Murphy, James M., Lalaoui, Najoua, Hildebrand, Joanne M., Silke, John, Alexander, Warren S., Josefsson, Emma C.
Publicado 2021

SOCS2 regulation of growth hormone signaling requires a canonical interaction with phosphotyrosine

por Li, Kunlun, Meza Guzman, Lizeth G., Whitehead, Lachlan, Leong, Evelyn, Kueh, Andrew, Alexander, Warren S., Kershaw, Nadia J., Babon, Jeffrey J., Doggett, Karen, Nicholson, Sandra E.
Publicado 2022

Necroptotic signaling is primed in Mycobacterium tuberculosis-infected macrophages, but its pathophysiological consequence in disease is restricted

por Stutz, Michael D., Ojaimi, Samar, Allison, Cody, Preston, Simon, Arandjelovic, Philip, Hildebrand, Joanne M., Sandow, Jarrod J., Webb, Andrew I., Silke, John, Alexander, Warren S., Pellegrini, Marc
Publicado 2017

Mutually exclusive regulation of T cell survival by IL-7R and antigen receptor-induced signals

por Koenen, Paul, Heinzel, Susanne, Carrington, Emma M., Happo, Lina, Alexander, Warren S., Zhang, Jian-Guo, Herold, Marco J., Scott, Clare L., Lew, Andrew M., Strasser, Andreas, Hodgkin, Philip D.
Publicado 2013

Overexpression of Lmo2 initiates T-lymphoblastic leukemia via impaired thymocyte competition

por Abdulla, Hesham D., Alserihi, Raed, Flensburg, Christoffer, Abeysekera, Waruni, Luo, Meng-Xiao, Gray, Daniel H.D., Liu, Xiaodong, Smyth, Gordon K., Alexander, Warren S., Majewski, Ian J., McCormack, Matthew P.
Publicado 2023

Defective Gp130-Mediated Signal Transducer and Activator of Transcription (Stat) Signaling Results in Degenerative Joint Disease, Gastrointestinal Ulceration, and Failure of Uterin...

por Ernst, Matthias, Inglese, Melissa, Waring, Paul, Campbell, Ian K., Bao, Shisan, Clay, Fiona J., Alexander, Warren S., Wicks, Ian P., Tarlinton, David M., Novak, Ulrike, Heath, Joan K., Dunn, Ashley R.
Publicado 2001

IL-6 promotes acute and chronic inflammatory disease in the absence of SOCS3

por Croker, Ben A, Kiu, Hiu, Pellegrini, Marc, Toe, Jesse, Preston, Simon, Metcalf, Donald, O’Donnell, Joanne A, Cengia, Louise H, McArthur, Kate, Nicola, Nicos A, Alexander, Warren S, Roberts, Andrew W
Publicado 2011

Early Lineage Priming by Trisomy of Erg Leads to Myeloproliferation in a Down Syndrome Model

por Ng, Ashley P., Hu, Yifang, Metcalf, Donald, Hyland, Craig D., Ierino, Helen, Phipson, Belinda, Wu, Di, Baldwin, Tracey M., Kauppi, Maria, Kiu, Hiu, Di Rago, Ladina, Hilton, Douglas J., Smyth, Gordon K., Alexander, Warren S.
Publicado 2015

Acute myeloid leukemia requires Hhex to enable PRC2-mediated epigenetic repression of Cdkn2a

por Shields, Benjamin J., Jackson, Jacob T., Metcalf, Donald, Shi, Wei, Huang, Qiutong, Garnham, Alexandra L., Glaser, Stefan P., Beck, Dominik, Pimanda, John E., Bogue, Clifford W., Smyth, Gordon K., Alexander, Warren S., McCormack, Matthew P.
Publicado 2016

Polycomb Repressive Complex 2 (PRC2) Restricts Hematopoietic Stem Cell Activity

por Majewski, Ian J, Blewitt, Marnie E, de Graaf, Carolyn A, McManus, Edward J, Bahlo, Melanie, Hilton, Adrienne A, Hyland, Craig D, Smyth, Gordon K, Corbin, Jason E, Metcalf, Donald, Alexander, Warren S, Hilton, Douglas J
Publicado 2008

Proinflammatory microenvironment promotes lymphoma progression in mice with high megakaryocyte and TPO levels

por Au, Amanda E., Corbin, Jason, Lebois, Marion, Gangatirkar, Pradnya, Yassinson, Fatme, Hyslop, Stephanie R., Cannon, Ping, Mason, Kylie D., Li-Wai-Suen, Connie S. N., Garnham, Alexandra L., Moujalled, Diane, Cimmino, Luisa, Alexander, Warren S., Josefsson, Emma C.
Publicado 2022

Altered B-lymphopoiesis in mice with deregulated thrombopoietin signaling

por Au, Amanda E., Lebois, Marion, Sim, Starling A., Cannon, Ping, Corbin, Jason, Gangatirkar, Pradnya, Hyland, Craig D., Moujalled, Diane, Rutgersson, Angelika, Yassinson, Fatme, Kile, Benjamin T., Mason, Kylie D., Ng, Ashley P., Alexander, Warren S., Josefsson, Emma C.
Publicado 2017

Canonical PRC2 function is essential for mammary gland development and affects chromatin compaction in mammary organoids

por Michalak, Ewa M., Milevskiy, Michael J. G., Joyce, Rachel M., Dekkers, Johanna F., Jamieson, Paul R., Pal, Bhupinder, Dawson, Caleb A., Hu, Yifang, Orkin, Stuart H., Alexander, Warren S., Lindeman, Geoffrey J., Smyth, Gordon K., Visvader, Jane E.
Publicado 2018

Altered microbiota by a high-fat diet accelerates lethal myeloid hematopoiesis associated with systemic SOCS3 deficiency

por Cho, Kaori, Ushiki, Takashi, Ishiguro, Hajime, Tamura, Suguru, Araki, Masaya, Suwabe, Tatsuya, Katagiri, Takayuki, Watanabe, Mari, Fujimoto, Yoko, Ohashi, Riuko, Ajioka, Yoichi, Shimizu, Ippei, Okuda, Shujiro, Masuko, Masayoshi, Nakagawa, Yoshimi, Hirai, Hideyo, Alexander, Warren S., Shimano, Hitoshi, Sone, Hirohito
Publicado 2021

Identification of a Siglec-F+ granulocyte-macrophage progenitor

por Bolden, Jessica E., Lucas, Erin C., Zhou, Geyu, O’Sullivan, Jeremy A., de Graaf, Carolyn A., McKenzie, Mark D., Di Rago, Ladina, Baldwin, Tracey M., Shortt, Jake, Alexander, Warren S., Bochner, Bruce S., Ritchie, Matthew E., Hilton, Douglas J., Fairfax, Kirsten A.
Publicado 2018

Correction: NK cell–derived GM-CSF potentiates inflammatory arthritis and is negatively regulated by CIS

por Louis, Cynthia, Souza-Fonseca-Guimaraes, Fernando, Yang, Yuyan, D’Silva, Damian, Kratina, Tobias, Dagley, Laura, Hediyeh-Zadeh, Soroor, Rautela, Jai, Masters, Seth Lucian, Davis, Melissa J., Babon, Jeffrey J., Ciric, Bogoljub, Vivier, Eric, Alexander, Warren S., Huntington, Nicholas D., Wicks, Ian P.
Publicado 2020