Mutational signatures: the patterns of somatic mutations hidden in cancer genomes()

por Alexandrov, Ludmil B, Stratton, Michael R
Publicado 2014

Computer Modeling Describes Gravity-Related Adaptation in Cell Cultures

por Alexandrov, Ludmil B., Alexandrova, Stoyana, Usheva, Anny
Publicado 2009

An overview of mutational and copy number signatures in human cancer

por Steele, Christopher D, Pillay, Nischalan, Alexandrov, Ludmil B
Publicado 2022

Insights into BRCA Cancer Predisposition from Integrated Germline and Somatic Analyses in 7632 Cancers

por Yost, Shawn, Ruark, Elise, Alexandrov, Ludmil B, Rahman, Nazneen
Publicado 2019

Generating realistic null hypothesis of cancer mutational landscapes using SigProfilerSimulator

por Bergstrom, Erik N., Barnes, Mark, Martincorena, Iñigo, Alexandrov, Ludmil B.
Publicado 2020

Examining clustered somatic mutations with SigProfilerClusters

por Bergstrom, Erik N, Kundu, Mousumy, Tbeileh, Noura, Alexandrov, Ludmil B
Publicado 2022

The role of structural parameters in DNA cyclization

por Alexandrov, Ludmil B., Bishop, Alan R., Rasmussen, Kim Ø., Alexandrov, Boian S.
Publicado 2016

Evaluating the role of coherent delocalized phonon-like modes in DNA cyclization

por Alexandrov, Ludmil B., Rasmussen, Kim Ø., Bishop, Alan R., Alexandrov, Boian S.
Publicado 2017

Nonnegative/Binary matrix factorization with a D-Wave quantum annealer

por O’Malley, Daniel, Vesselinov, Velimir V., Alexandrov, Boian S., Alexandrov, Ludmil B.
Publicado 2018

Somatic mutational profiles and germline polygenic risk scores in human cancer

por Liu, Yuxi, Gusev, Alexander, Heng, Yujing J., Alexandrov, Ludmil B., Kraft, Peter
Publicado 2022

Deciphering Signatures of Mutational Processes Operative in Human Cancer

por Alexandrov, Ludmil B., Nik-Zainal, Serena, Wedge, David C., Campbell, Peter J., Stratton, Michael R.
Publicado 2013

A mutational signature in gastric cancer suggests therapeutic strategies

por Alexandrov, Ludmil B., Nik-Zainal, Serena, Siu, Hoi Cheong, Leung, Suet Yi, Stratton, Michael R
Publicado 2015

Topography of mutational signatures in human cancer

por Otlu, Burçak, Díaz-Gay, Marcos, Vermes, Ian, Bergstrom, Erik N., Zhivagui, Maria, Barnes, Mark, Alexandrov, Ludmil B.
Publicado 2023

A nonlinear dynamic model of DNA with a sequence-dependent stacking term

por Alexandrov, Boian S., Gelev, Vladimir, Monisova, Yevgeniya, Alexandrov, Ludmil B., Bishop, Alan R., Rasmussen, Kim Ø., Usheva, Anny
Publicado 2009

SigProfilerMatrixGenerator: a tool for visualizing and exploring patterns of small mutational events

por Bergstrom, Erik N., Huang, Mi Ni, Mahto, Uma, Barnes, Mark, Stratton, Michael R., Rozen, Steven G., Alexandrov, Ludmil B.
Publicado 2019

DNA dynamics play a role as a basal transcription factor in the positioning and regulation of gene transcription initiation

por Alexandrov, Boian S., Gelev, Vladimir, Yoo, Sang Wook, Alexandrov, Ludmil B., Fukuyo, Yayoi, Bishop, Alan R., Rasmussen, Kim Ø., Usheva, Anny
Publicado 2010

Strength of immune selection in tumors varies with sex and age

por Castro, Andrea, Pyke, Rachel Marty, Zhang, Xinlian, Thompson, Wesley Kurt, Day, Chi-Ping, Alexandrov, Ludmil B., Zanetti, Maurizio, Carter, Hannah
Publicado 2020

Visualizing and exploring patterns of large mutational events with SigProfilerMatrixGenerator

por Khandekar, Azhar, Vangara, Raviteja, Barnes, Mark, Díaz-Gay, Marcos, Abbasi, Ammal, Bergstrom, Erik N., Steele, Christopher D., Pillay, Nischalan, Alexandrov, Ludmil B.
Publicado 2023

Author Correction: DNA damage and somatic mutations in mammalian cells after irradiation with a nail polish dryer

por Zhivagui, Maria, Hoda, Areebah, Valenzuela, Noelia, Yeh, Yi-Yu, Dai, Jason, He, Yudou, Nandi, Shuvro P., Otlu, Burcak, Van Houten, Bennett, Alexandrov, Ludmil B.
Publicado 2023

DNA Dynamics Is Likely to Be a Factor in the Genomic Nucleotide Repeats Expansions Related to Diseases

por Alexandrov, Boian S., Valtchinov, Vlad I., Alexandrov, Ludmil B., Gelev, Vladimir, Dagon, Yossi, Bock, Jonathan, Kohane, Isaac S., Rasmussen, Kim Ø., Bishop, Alan R., Usheva, Anny
Publicado 2011