Nonsense-Mediated mRNA Decay: Pathologies and the Potential for Novel Therapeutics

por Pawlicka, Kamila, Kalathiya, Umesh, Alfaro, Javier
Publicado 2020

Mass Spectrometry-Based Identification of MHC-Associated Peptides

por Kote, Sachin, Pirog, Artur, Bedran, Georges, Alfaro, Javier, Dapic, Irena
Publicado 2020

Recognition Dynamics of Cancer Mutations on the ERp57-Tapasin Interface

por Padariya, Monikaben, Kalathiya, Umesh, Houston, Douglas R., Alfaro, Javier Antonio
Publicado 2020

Detecting protein variants by mass spectrometry: a comprehensive study in cancer cell-lines

por Alfaro, Javier A., Ignatchenko, Alexandr, Ignatchenko, Vladimir, Sinha, Ankit, Boutros, Paul C., Kislinger, Thomas
Publicado 2017

Insights into the Effects of Cancer Associated Mutations at the UPF2 and ATP-Binding Sites of NMD Master Regulator: UPF1

por Kalathiya, Umesh, Padariya, Monikaben, Pawlicka, Kamila, Verma, Chandra S., Houston, Douglas, Hupp, Ted R., Alfaro, Javier Antonio
Publicado 2019

Structural determinants of peptide-dependent TAP1-TAP2 transit passage targeted by viral proteins and altered by cancer-associated mutations

por Padariya, Monikaben, Kote, Sachin, Mayordomo, Marcos, Dapic, Irena, Alfaro, Javier, Hupp, Ted, Fahraeus, Robin, Kalathiya, Umesh
Publicado 2021

Interfaces with Structure Dynamics of the Workhorses from Cells Revealed through Cross-Linking Mass Spectrometry (CLMS)

por Kalathiya, Umesh, Padariya, Monikaben, Faktor, Jakub, Coyaud, Etienne, Alfaro, Javier A., Fahraeus, Robin, Hupp, Ted R., Goodlett, David R.
Publicado 2021

Unraveling the glycosylated immunopeptidome with HLA-Glyco

por Bedran, Georges, Polasky, Daniel A., Hsiao, Yi, Yu, Fengchao, da Veiga Leprevost, Felipe, Alfaro, Javier A., Cieslik, Marcin, Nesvizhskii, Alexey I.
Publicado 2023

Functional Interfaces, Biological Pathways, and Regulations of Interferon-Related DNA Damage Resistance Signature (IRDS) Genes

por Padariya, Monikaben, Sznarkowska, Alicja, Kote, Sachin, Gómez-Herranz, Maria, Mikac, Sara, Pilch, Magdalena, Alfaro, Javier, Fahraeus, Robin, Hupp, Ted, Kalathiya, Umesh
Publicado 2021

Aberrant DNA methylation reprogramming during induced pluripotent stem cell generation is dependent on the choice of reprogramming factors

por Planello, Aline C, Ji, Junfeng, Sharma, Vivek, Singhania, Rajat, Mbabaali, Faridah, Müller, Fabian, Alfaro, Javier A, Bock, Christoph, De Carvalho, Daniel D, Batada, Nizar N
Publicado 2014

Gorham-Stout case report: a multi-omic analysis reveals recurrent fusions as new potential drivers of the disease

por Yébenes Mayordomo, Marcos, Al Shboul, Sofian, Gómez-Herranz, Maria, Azfer, Asim, Meynert, Alison, Salter, Donald, Hayward, Larry, Oniscu, Anca, Patton, James T., Hupp, Ted, Arends, Mark J., Alfaro, Javier Antonio
Publicado 2022

Highly Conserved Homotrimer Cavity Formed by the SARS-CoV-2 Spike Glycoprotein: A Novel Binding Site

por Kalathiya, Umesh, Padariya, Monikaben, Mayordomo, Marcos, Lisowska, Małgorzata, Nicholson, Judith, Singh, Ashita, Baginski, Maciej, Fahraeus, Robin, Carragher, Neil, Ball, Kathryn, Haas, Juergen, Daniels, Alison, Hupp, Ted R., Alfaro, Javier Antonio
Publicado 2020

Kinomics platform using GBM tissue identifies BTK as being associated with higher patient survival

por Al Shboul, Sofian, Curran, Olimpia E, Alfaro, Javier A, Lickiss, Fiona, Nita, Erisa, Kowalski, Jacek, Naji, Faris, Nenutil, Rudolf, Ball, Kathryn L, Krejcir, Radovan, Vojtesek, Borivoj, Hupp, Ted R, Brennan, Paul M
Publicado 2021

MicroPOTS Analysis of Barrett’s Esophageal Cell Line Models Identifies Proteomic Changes after Physiologic and Radiation Stress

por Weke, Kenneth, Singh, Ashita, Uwugiaren, Naomi, Alfaro, Javier A., Wang, Tongjie, Hupp, Ted R., O’Neill, J. Robert, Vojtesek, Borek, Goodlett, David R., Williams, Sarah M., Zhou, Mowei, Kelly, Ryan T., Zhu, Ying, Dapic, Irena
Publicado 2021

The Immunopeptidome from a Genomic Perspective: Establishing the Noncanonical Landscape of MHC Class I–Associated Peptides

por Bedran, Georges, Gasser, Hans-Christof, Weke, Kenneth, Wang, Tongjie, Bedran, Dominika, Laird, Alexander, Battail, Christophe, Zanzotto, Fabio Massimo, Pesquita, Catia, Axelson, Håkan, Rajan, Ajitha, Harrison, David J., Palkowski, Aleksander, Pawlik, Maciej, Parys, Maciej, O'Neill, J. Robert, Brennan, Paul M., Symeonides, Stefan N., Goodlett, David R., Litchfield, Kevin, Fahraeus, Robin, Hupp, Ted R., Kote, Sachin, Alfaro, Javier A.
Publicado 2023