Pharmacogenomics and personalized medicine: the plunge into next-generation sequencing

por Wadelius, Mia, Alfirevic, Ana
Publicado 2011

Drug Induced Hypersensitivity and the HLA Complex

por Alfirevic, Ana, Pirmohamed, Munir
Publicado 2010

Editorial: Emerging talents in frontiers in pharmacology: pharmacogenetics and pharmacogenomics 2022

por Klomp, Sylvia D., Alfirevic, Ana
Publicado 2023

Systematic review of preterm birth multi-omic biomarker studies

por Gupta, Juhi K., Alfirevic, Ana
Publicado 2022

Pharmacogenomics: Current State-of-the-Art

por Carr, Daniel F., Alfirevic, Ana, Pirmohamed, Munir
Publicado 2014

Pharmacogenetics and pharmacogenomics: practical applications in routine medical practice

por Maitland-van der Zee, Anke-Hilse, Alfirevic, Ana
Publicado 2010

Developing In Vitro Models to Define the Role of Direct Mitochondrial Toxicity in Frequently Reported Drug-Induced Rhabdomyolysis

por Bin Dayel, Faten F., Alfirevic, Ana, Chadwick, Amy E.
Publicado 2023

Pathway Analysis of Genetic Factors Associated with Spontaneous Preterm Birth and Pre-Labor Preterm Rupture of Membranes

por Capece, Antonio, Vasieva, Olga, Meher, Shireen, Alfirevic, Zarko, Alfirevic, Ana
Publicado 2014

The Role of Mitochondrial DNA Variation in Drug Response: A Systematic Review

por Jones, Samantha W., Ball, Amy L., Chadwick, Amy E., Alfirevic, Ana
Publicado 2021

Has the introduction of direct oral anticoagulants (DOACs) in England increased emergency admissions for bleeding conditions? A longitudinal ecological study

por Alfirevic, Ana, Downing, Jennifer, Daras, Konstantinos, Comerford, Terence, Pirmohamed, Munir, Barr, Ben
Publicado 2020

Identification of the Additional Mitochondrial Liabilities of 2-Hydroxyflutamide When Compared With its Parent Compound, Flutamide in HepG2 Cells

por Ball, Amy L., Kamalian, Laleh, Alfirevic, Ana, Lyon, Jonathan J., Chadwick, Amy E.
Publicado 2016

Genome and transcriptome profiling of spontaneous preterm birth phenotypes

por Gupta, Juhi K., Care, Angharad, Goodfellow, Laura, Alfirevic, Zarko, Müller-Myhsok, Bertram, Alfirevic, Ana
Publicado 2022

Publisher Correction: Genome and transcriptome profiling of spontaneous preterm birth phenotypes

por Gupta, Juhi K., Care, Angharad, Goodfellow, Laura, Alfirevic, Zarko, Müller‑Myhsok, Bertram, Alfirevic, Ana
Publicado 2022

Establishment of an HLA-typed cohort of 1000 healthy blood donors and use of a dendritic cell priming assay to prime naive T cells to structurally divergent drugs

por Faulkner, Lee, Wood, Sally, Van Eker, Diane, Alfirevic, Ana, Pirmohamed, Munir, Naisbitt, Dean, Park, Kevin
Publicado 2014

Skewing of the TCR V repertoire in SMX-NO specific T cell responses

por Faulkner, Lee, Lichtenfels, Maike, Esser, Philipp, Martin, Stefan, Alfirevic, Ana, Pirmohamed, Munir, Naisbitt, Dean, Park, Kevin
Publicado 2014

The generation of HepG2 transmitochondrial cybrids to reveal the role of mitochondrial genotype in idiosyncratic drug-induced liver injury

por Ball, Amy Louise, Jolly, Carol E, Lennon, Mark G, Lyon, Jonathan J, Alfirevic, Ana, Chadwick, Amy E
Publicado 2023

Characterization of amoxicillin and clavulanic-acid-responsive CD4+ And CD8+ T-cells in patients with co-amoxiclav-induced liver injury

por Kim, Seung-Hyun, Saide, Katy, Yuan, Ye, Daly, Ann, Alfirevic, Ana, Pirmohamed, Munir, Park, Kevin, Naisbitt, Dean
Publicado 2014

Identification of susceptible HLA class II co-amoxiclav genotypes based on the analysis of drug-specific T-cells from patients with liver injury

por Saide, Katy, Kim, Seung-Hyun, Yuan, Ye, Daly, Ann, Alfirevic, Ana, Pirmohamed, Munir, Park, Kevin, Naisbitt, Dean
Publicado 2014

Characterization of Drug-Specific CD4(+) T-Cells Reveals Possible Roles of HLA Class II in the Pathogenesis of Carbamazepine Hypersensitivity Reactions

por Jaruthamsophon, Kanoot, Thomson, Paul J., Hammond, Sean, Zhang, Eunice, Alfirevic, Ana, Sukasem, Chonlaphat, Naisbitt, Dean J., Pirmohamed, Munir
Publicado 2023

HLA-DQ restricted activation of nitroso-sulfamethoxazole-specific CD4+ T-lymphocytes

por Ogese, Monday, Saide, Katy, Whitaker, Paul, Peckham, Daniel, Faulkner, Lee, Alfirevic, Ana, Pirmohamed, Munir, Park, Kevin, Naisbitt, Dean
Publicado 2014