Dual BRCA1 and BRCA2 pathogenic variants in an adolescent with syndromic intellectual disability

por Algouneh, Arash, Caudle, Michelle, Balci, Tugce, Andrade, Andrea, Penava, Debbie, Saleh, Maha
Publicado 2022

Excessive transcription-replication conflicts are a vulnerability of BRCA1-mutant cancers

por Patel, Parasvi S, Algouneh, Arash, Krishnan, Rehna, Reynolds, John J, Nixon, Kevin C J, Hao, Jun, Lee, Jihoon, Feng, Yue, Fozil, Chehronai, Stanic, Mia, Yerlici, Talya, Su, Peiran, Soares, Fraser, Liedtke, Elisabeth, Prive, Gil, Baider, Gary D, Pujana, Miquel Angel, Mekhail, Karim, He, Housheng Hansen, Hakem, Anne, Stewart, Grant S, Hakem, Razqallah
Publicado 2023

IPO11 regulates the nuclear import of BZW1/2 and is necessary for AML cells and stem cells

por Nachmias, Boaz, Khan, Dilshad H., Voisin, Veronique, Mer, Arvind S., Thomas, Geethu Emily, Segev, Nadav, St-Germain, Jonathan, Hurren, Rose, Gronda, Marcela, Botham, Aaron, Wang, Xiaoming, Maclean, Neil, Seneviratne, Ayesh K., Duong, Nathan, Xu, Changjiang, Arruda, Andrea, Orouji, Elias, Algouneh, Arash, Hakem, Razqallah, Shlush, Liran, Minden, Mark D., Raught, Brian, Bader, Gary D., Schimmer, Aaron D.
Publicado 2022

Nucleolar RNA polymerase II drives ribosome biogenesis

por Abraham, Karan J., Khosraviani, Negin, Chan, Janet N.Y., Gorthi, Aparna, Samman, Anas, Zhao, Dorothy Y., Wang, Miling, Bokros, Michael, Vidya, Elva, Ostrowski, Lauren A., Oshidari, Roxanne, Pietrobon, Violena, Patel, Parasvi, Algouneh, Arash, Singhania, Rajat, Liu, Yupeng, Yerlici, V. Talya, De Carvalho, Daniel D., Ohh, Michael, Dickson, Brendan C., Hakem, Razq, Greenblatt, Jack F., Lee, Stephen, Bishop, Alexander J. R., Mekhail, Karim
Publicado 2020

RNF8 ubiquitylation of XRN2 facilitates R-loop resolution and restrains genomic instability in BRCA1 mutant cells

por Krishnan, Rehna, Lapierre, Mariah, Gautreau, Brandon, Nixon, Kevin C J, El Ghamrasni, Samah, Patel, Parasvi S, Hao, Jun, Yerlici, V Talya, Guturi, Kiran Kumar Naidu, St-Germain, Jonathan, Mateo, Francesca, Saad, Amine, Algouneh, Arash, Earnshaw, Rebecca, Shili, Duan, Seitova, Alma, Miller, Joshua, Khosraviani, Negin, Penn, Adam, Ho, Brandon, Sanchez, Otto, Hande, M Prakash, Masson, Jean-Yves, Brown, Grant W, Alaoui-Jamali, Moulay, Reynolds, John J, Arrowsmith, Cheryl, Raught, Brian, Pujana, Miguel A, Mekhail, Karim, Stewart, Grant S, Hakem, Anne, Hakem, Razqallah
Publicado 2023