The Viral Macrodomain Counters Host Antiviral ADP-Ribosylation

por Alhammad, Yousef M. O., Fehr, Anthony R.
Publicado 2020

Longitudinal Sequence and Functional Evolution within Glycoprotein E2 in Hepatitis C Virus Genotype 3a Infection

por Alhammad, Yousef M. O., Maharajh, Sanvir, Butcher, Rebecca, Eden, John-Sebastian, White, Peter A., Poumbourios, Pantelis, Drummer, Heidi E
Publicado 2015

Monoclonal Antibodies Directed toward the Hepatitis C Virus Glycoprotein E2 Detect Antigenic Differences Modulated by the N-Terminal Hypervariable Region 1 (HVR1), HVR2, and Interg...

por Alhammad, Yousef, Gu, Jun, Boo, Irene, Harrison, David, McCaffrey, Kathleen, Vietheer, Patricia T., Edwards, Stirling, Quinn, Charles, Coulibaly, Fásseli, Poumbourios, Pantelis, Drummer, Heidi E.
Publicado 2015

Escape of Hepatitis C Virus from Epitope I Neutralization Increases Sensitivity of Other Neutralization Epitopes

por Gu, Jun, Hardy, Joshua, Boo, Irene, Vietheer, Patricia, McCaffrey, Kathleen, Alhammad, Yousef, Chopra, Abha, Gaudieri, Silvana, Poumbourios, Pantelis, Coulibaly, Fasséli, Drummer, Heidi E.
Publicado 2018

Discovery of compounds that inhibit SARS-CoV-2 Mac1-ADP-ribose binding by high-throughput screening

por Roy, Anu, Alhammad, Yousef M., McDonald, Peter, Johnson, David K., Zhuo, Junlin, Wazir, Sarah, Ferraris, Dana, Lehtiö, Lari, Leung, Anthony K.L., Fehr, Anthony R.
Publicado 2022

Coronavirus infection and PARP expression dysregulate the NAD Metabolome: an actionable component of innate immunity

por Heer, Collin D., Sanderson, Daniel J., Voth, Lynden S., Alhammad, Yousef M.O., Schmidt, Mark S., Trammell, Samuel A.J., Perlman, Stanley, Cohen, Michael S., Fehr, Anthony R., Brenner, Charles
Publicado 2020

Coronavirus infection and PARP expression dysregulate the NAD metabolome: An actionable component of innate immunity

por Heer, Collin D., Sanderson, Daniel J., Voth, Lynden S., Alhammad, Yousef M.O., Schmidt, Mark S., Trammell, Samuel A.J., Perlman, Stanley, Cohen, Michael S., Fehr, Anthony R., Brenner, Charles
Publicado 2021

Full-Length Genome of the Equine Influenza A Virus Subtype H3N8 from 2019 Outbreak in Saudi Arabia

por Alaql, Fanan A., Alhafufi, Ali N., Kasem, Samy, Alhammad, Yousef M. O., Albaqshi, Hassan, Alyousaf, Ameen, Alsubaie, Faisal M., Alghamdi, Ahmed N., Abdel-Moneim, Ahmed S., Alharbi, Sulaiman A.
Publicado 2022

SARS-CoV-2 Mac1 is required for IFN antagonism and efficient virus replication in mice

por Alhammad, Yousef M., Parthasarathy, Srivatsan, Ghimire, Roshan, O’Connor, Joseph J., Kerr, Catherine M., Pfannenstiel, Jessica J., Chanda, Debarati, Miller, Caden A., Unckless, Robert L., Zuniga, Sonia, Enjuanes, Luis, More, Sunil, Channappanavar, Rudragouda, Fehr, Anthony R.
Publicado 2023

The SARS-CoV-2 Conserved Macrodomain Is a Mono-ADP-Ribosylhydrolase

por Alhammad, Yousef M. O., Kashipathy, Maithri M., Roy, Anuradha, Gagné, Jean-Philippe, McDonald, Peter, Gao, Philip, Nonfoux, Louis, Battaile, Kevin P., Johnson, David K., Holmstrom, Erik D., Poirier, Guy G., Lovell, Scott, Fehr, Anthony R.
Publicado 2021

Design, synthesis and evaluation of inhibitors of the SARS-CoV-2 nsp3 macrodomain

por Sherrill, Lavinia M., Joya, Elva E., Walker, AnnMarie, Roy, Anuradha, Alhammad, Yousef M., Atobatele, Moriama, Wazir, Sarah, Abbas, George, Keane, Patrick, Zhuo, Junlin, Leung, Anthony K.L., Johnson, David K., Lehtiö, Lari, Fehr, Anthony R., Ferraris, Dana
Publicado 2022

SARS-CoV-2 Mac1 is required for IFN antagonism and efficient virus replication in cell culture and in mice

por Alhammad, Yousef M., Parthasarathy, Srivatsan, Ghimire, Roshan, Kerr, Catherine M., O’Connor, Joseph J., Pfannenstiel, Jessica J., Chanda, Debarati, Miller, Caden A., Baumlin, Nathalie, Salathe, Matthias, Unckless, Robert L., Zuñiga, Sonia, Enjuanes, Luis, More, Sunil, Channappanavar, Rudragouda, Fehr, Anthony R.
Publicado 2023

Circulation of Influenza A(H5N8) Virus, Saudi Arabia

por Al-Ghadeer, Hussain, Chu, Daniel K.W., Rihan, Ehab M.A., Abd-Allah, Ehab M., Gu, Haogao, Chin, Alex W.H., Qasim, Ibrahim A., Aldoweriej, Ali, Alharbi, Sanad S., Al-Aqil, Marshad A., Al-Sahaf, Ali, Abdel Rahman, Salah S., Aljassem, Ali H., Abdul-Al, Ali, Aljasir, Mohammed R., Alhammad, Yousef M.O., Kasem, Samy, Peiris, Malik, Zaki, Ahmed Z.S.A., Poon, Leo L.M.
Publicado 2018