In vivo DNA-launched bispecific T cell engager targeting IL-13Rα2 controls tumor growth in an animal model of glioblastoma multiforme

por Bhojnagarwala, Pratik S., O’Connell, Ryan P., Park, Daniel, Liaw, Kevin, Ali, Ali R., Bordoloi, Devivasha, Cassel, Joel, Tursi, Nicholas J., Gary, Ebony, Weiner, David B.
Publicado 2022

Multivalent in vivo delivery of DNA-encoded bispecific T cell engagers effectively controls heterogeneous GBM tumors and mitigates immune escape

por Park, Daniel H., Liaw, Kevin, Bhojnagarwala, Pratik, Zhu, Xizhou, Choi, Jihae, Ali, Ali R., Bordoloi, Devivasha, Gary, Ebony N., O’Connell, Ryan P., Kulkarni, Abhijeet, Guimet, Diana, Smith, Trevor, Perales-Puchalt, Alfredo, Patel, Ami, Weiner, David B.
Publicado 2023

Siglec-7 glyco-immune binding mAbs or NK cell engager biologics induce potent antitumor immunity against ovarian cancers

por Bordoloi, Devivasha, Kulkarni, Abhijeet J., Adeniji, Opeyemi S., Pampena, M. Betina, Bhojnagarwala, Pratik S., Zhao, Shushu, Ionescu, Candice, Perales-Puchalt, Alfredo, Parzych, Elizabeth M., Zhu, Xizhou, Ali, Ali R., Cassel, Joel, Zhang, Rugang, Betts, Michael R., Abdel-Mohsen, Mohamed, Weiner, David B.
Publicado 2023

Mucosal chemokine adjuvant enhances synDNA vaccine-mediated responses to SARS-CoV-2 and provides heterologous protection in vivo

por Gary, Ebony N., Tursi, Nicholas J., Warner, Bryce, Parzych, Elizabeth M., Ali, Ali R., Frase, Drew, Moffat, Estella, Embury-Hyatt, Carissa, Smith, Trevor R.F., Broderick, Kate E., Humeau, Laurent, Kobasa, Darwyn, Patel, Ami, Kulp, Daniel W., Weiner, David B.
Publicado 2022

Adenosine deaminase augments SARS-CoV-2 specific cellular and humoral responses in aged mouse models of immunization and challenge

por Gary, Ebony N., Tursi, Nicholas J., Warner, Bryce M., Cuismano, Gina, Connors, Jennifer, Parzych, Elizabeth M., Griffin, Bryan D., Bell, Matthew R., Ali, Ali R., Frase, Drew, Hojecki, Casey E., Canziani, Gabriela A., Chaiken, Irwin, Kannan, Toshitha, Moffat, Estella, Embury-Hyatt, Carissa, Wooton, Sarah K., Kossenkov, Andrew, Patel, Ami, Kobasa, Darwyn, Kutzler, Michele A., Haddad, Elias K., Weiner, David B.
Publicado 2023

A novel mouse AAV6 hACE2 transduction model of wild-type SARS-CoV-2 infection studied using synDNA immunogens

por Gary, Ebony N., Warner, Bryce M., Parzych, Elizabeth M., Griffin, Bryan D., Zhu, Xizhou, Tailor, Nikesh, Tursi, Nicholas J., Chan, Mable, Purwar, Mansi, Vendramelli, Robert, Choi, Jihae, Frost, Kathy L., Reeder, Sophia, Liaw, Kevin, Tello, Edgar, Ali, Ali R., Yun, Kun, Pei, Yanlong, Thomas, Sylvia P., Rghei, Amira D., Guilleman, Matthew M., Muthumani, Kar, Smith, Trevor, Wootton, Sarah K., Patel, Ami, Weiner, David B., Kobasa, Darwyn
Publicado 2021

Debulking SARS-CoV-2 in saliva using angiotensin converting enzyme 2 in chewing gum to decrease oral virus transmission and infection

por Daniell, Henry, Nair, Smruti K., Esmaeili, Nardana, Wakade, Geetanjali, Shahid, Naila, Ganesan, Prem Kumar, Islam, Md Reyazul, Shepley-McTaggart, Ariel, Feng, Sheng, Gary, Ebony N., Ali, Ali R., Nuth, Manunya, Cruz, Selene Nunez, Graham-Wooten, Jevon, Streatfield, Stephen J., Montoya-Lopez, Ruben, Kaznica, Paul, Mawson, Margaret, Green, Brian J., Ricciardi, Robert, Milone, Michael, Harty, Ronald N., Wang, Ping, Weiner, David B., Margulies, Kenneth B., Collman, Ronald G.
Publicado 2022

DNA-delivered antibody cocktail exhibits improved pharmacokinetics and confers prophylactic protection against SARS-CoV-2

por Parzych, Elizabeth M., Du, Jianqiu, Ali, Ali R., Schultheis, Katherine, Frase, Drew, Smith, Trevor R. F., Cui, Jiayan, Chokkalingam, Neethu, Tursi, Nicholas J., Andrade, Viviane M., Warner, Bryce M., Gary, Ebony N., Li, Yue, Choi, Jihae, Eisenhauer, Jillian, Maricic, Igor, Kulkarni, Abhijeet, Chu, Jacqueline D., Villafana, Gabrielle, Rosenthal, Kim, Ren, Kuishu, Francica, Joseph R., Wootton, Sarah K., Tebas, Pablo, Kobasa, Darwyn, Broderick, Kate E., Boyer, Jean D., Esser, Mark T., Pallesen, Jesper, Kulp, Dan W., Patel, Ami, Weiner, David B.
Publicado 2022