90 Years of progesterone: Ninety years of progesterone: the ‘other’ ovarian hormone

por Ali, Simak, Balachandran, Kirsty, O’Malley, Bert
Publicado 2020

2.5 Å-resolution structure of human CDK-activating kinase bound to the clinical inhibitor ICEC0942

por Greber, Basil J., Remis, Jonathan, Ali, Simak, Nogales, Eva
Publicado 2021

Phosphorylation at serines 104 and 106 by Erk1/2 MAPK is important for estrogen receptor-α activity

por Thomas, Ross S, Sarwar, Naveed, Phoenix, Fladia, Coombes, R Charles, Ali, Simak
Publicado 2008

Development of a Novel Molecular Sensor for Imaging Estrogen Receptor-Coactivator Protein-Protein Interactions

por Lake, Madryn C., Nguyen, Quang-Dé, Ali, Simak, Aboagye, Eric O.
Publicado 2012

CDK7 inhibitors as anticancer drugs

por Sava, Georgina P., Fan, Hailing, Coombes, R. Charles, Buluwela, Lakjaya, Ali, Simak
Publicado 2020

The responses of cancer cells to PLK1 inhibitors reveal a novel protective role for p53 in maintaining centrosome separation

por Smith, Linda, Farzan, Raed, Ali, Simak, Buluwela, Laki, Saurin, Adrian T., Meek, David W.
Publicado 2017

Author Correction: The responses of cancer cells to PLK1 inhibitors reveal a novel protective role for p53 in maintaining centrosome separation

por Smith, Linda, Farzan, Raed, Ali, Simak, Buluwela, Laki, T. Saurin, Adrian, Meek, David W.
Publicado 2018

Characterisation of the androgen regulation of glycine N-methyltransferase in prostate cancer cells

por Ottaviani, Silvia, Brooke, Greg N, O'Hanlon-Brown, Ciara, Waxman, Jonathan, Ali, Simak, Buluwela, Laki
Publicado 2013

Engineered repressors are potent inhibitors of androgen receptor activity

por Brooke, Greg N., Powell, Sue M., Lavery, Derek N., Waxman, Jonathan, Buluwela, Laki, Ali, Simak, Bevan, Charlotte L.
Publicado 2014

Light-triggered enzymatic reactions in nested vesicle reactors

por Hindley, James W., Elani, Yuval, McGilvery, Catriona M., Ali, Simak, Bevan, Charlotte L., Law, Robert V., Ces, Oscar
Publicado 2018

Activating transcription factor-2 (ATF2) is a key determinant of resistance to endocrine treatment in an in vitro model of breast cancer

por Giannoudis, Athina, Malki, Mohammed Imad, Rudraraju, Bharath, Mohhamed, Hisham, Menon, Suraj, Liloglou, Triantafillos, Ali, Simak, Carroll, Jason S., Palmieri, Carlo
Publicado 2020

The CDK4/6 Inhibitor Palbociclib Inhibits Estrogen-Positive and Triple Negative Breast Cancer Bone Metastasis In Vivo

por Saleh, Lubaid, Ottewell, Penelope D., Brown, Janet E., Wood, Steve L., Brown, Nichola J., Wilson, Caroline, Park, Catherine, Ali, Simak, Holen, Ingunn
Publicado 2023

ABC-transporter upregulation mediates resistance to the CDK7 inhibitors THZ1 and ICEC0942

por Sava, Georgina P., Fan, Hailing, Fisher, Rosemary A., Lusvarghi, Sabrina, Pancholi, Sunil, Ambudkar, Suresh V., Martin, Lesley-Ann, Charles Coombes, R., Buluwela, Lakjaya, Ali, Simak
Publicado 2019

Induction of APOBEC3-mediated genomic damage in urothelium implicates BK polyomavirus (BKPyV) as a hit-and-run driver for bladder cancer

por Baker, Simon C., Mason, Andrew S., Slip, Raphael G., Skinner, Katie T., Macdonald, Andrew, Masood, Omar, Harris, Reuben S., Fenton, Tim R., Periyasamy, Manikandan, Ali, Simak, Southgate, Jennifer
Publicado 2022

Epithelial-mesenchymal plasticity determines estrogen receptor positive breast cancer dormancy and epithelial reconversion drives recurrence

por Aouad, Patrick, Zhang, Yueyun, De Martino, Fabio, Stibolt, Céline, Ali, Simak, Ambrosini, Giovanna, Mani, Sendurai A., Maggs, Kelly, Quinn, Hazel M., Sflomos, George, Brisken, Cathrin
Publicado 2022

The Evolution of Affordable Technologies in Liquid Biopsy Diagnostics: The Key to Clinical Implementation

por Alexandrou, George, Mantikas, Katerina-Theresa, Allsopp, Rebecca, Yapeter, Calista Adele, Jahin, Myesha, Melnick, Taryn, Ali, Simak, Coombes, R. Charles, Toumazou, Christofer, Shaw, Jacqueline A., Kalofonou, Melpomeni
Publicado 2023

LRH-1 drives colon cancer cell growth by repressing the expression of the CDKN1A gene in a p53-dependent manner

por Kramer, Holly B., Lai, Chun-Fui, Patel, Hetal, Periyasamy, Manikandan, Lin, Meng-Lay, Feller, Stephan M., Fuller-Pace, Frances V., Meek, David W., Ali, Simak, Buluwela, Laki
Publicado 2016

ZNF366 is an estrogen receptor corepressor that acts through CtBP and histone deacetylases

por Lopez-Garcia, Jorge, Periyasamy, Manikandan, Thomas, Ross S., Christian, Mark, Leao, Maria, Jat, Parmjit, Kindle, Karin B., Heery, David M., Parker, Malcolm G., Buluwela, Lakjaya, Kamalati, Tahereh, Ali, Simak
Publicado 2006

Dissecting the predictive value of MAPK/AKT/estrogen-receptor phosphorylation axis in primary breast cancer to treatment response for tamoxifen over exemestane: a Translational Rep...

por Szijgyarto, Zsolt, Flach, Koen D., Opdam, Mark, Palmieri, Carlo, Linn, Sabine C., Wesseling, Jelle, Ali, Simak, Bliss, Judith M., Cheang, Maggie Chon U., Zwart, Wilbert, Coombes, R. Charles
Publicado 2019

Low Dose Iron Treatments Induce a DNA Damage Response in Human Endothelial Cells within Minutes

por Mollet, Inês G., Patel, Dilipkumar, Govani, Fatima S., Giess, Adam, Paschalaki, Koralia, Periyasamy, Manikandan, Lidington, Elaine C., Mason, Justin C., Jones, Michael D., Game, Laurence, Ali, Simak, Shovlin, Claire L.
Publicado 2016