Targeted Protein Degradation: Advances, Challenges, and Prospects for Computational Methods

por Mostofian, Barmak, Martin, Holli-Joi, Razavi, Asghar, Patel, Shivam, Allen, Bryce, Sherman, Woody, Izaguirre, Jesus A
Publicado 2023

Large-Scale Computational Screening Identifies First in Class Multitarget Inhibitor of EGFR Kinase and BRD4

por Allen, Bryce K., Mehta, Saurabh, Ember, Stewart W. J., Schonbrunn, Ernst, Ayad, Nagi, Schürer, Stephan C.
Publicado 2015

Identification of a Novel Class of BRD4 Inhibitors by Computational Screening and Binding Simulations

por Allen, Bryce K., Mehta, Saurabh, Ember, Stuart W. J., Zhu, Jin-Yi, Schönbrunn, Ernst, Ayad, Nagi G., Schürer, Stephan C.
Publicado 2017

BET bromodomain proteins are required for glioblastoma cell proliferation

por Pastori, Chiara, Daniel, Mark, Penas, Clara, Volmar, Claude-Henry, Johnstone, Andrea L, Brothers, Shaun P, Graham, Regina M, Allen, Bryce, Sarkaria, Jann N, Komotar, Ricardo J, Wahlestedt, Claes, Ayad, Nagi G
Publicado 2014

Data Portal for the Library of Integrated Network-based Cellular Signatures (LINCS) program: integrated access to diverse large-scale cellular perturbation response data

por Koleti, Amar, Terryn, Raymond, Stathias, Vasileios, Chung, Caty, Cooper, Daniel J, Turner, John P, Vidović, Dušica, Forlin, Michele, Kelley, Tanya T, D’Urso, Alessandro, Allen, Bryce K, Torre, Denis, Jagodnik, Kathleen M, Wang, Lily, Jenkins, Sherry L, Mader, Christopher, Niu, Wen, Fazel, Mehdi, Mahi, Naim, Pilarczyk, Marcin, Clark, Nicholas, Shamsaei, Behrouz, Meller, Jarek, Vasiliauskas, Juozas, Reichard, John, Medvedovic, Mario, Ma’ayan, Avi, Pillai, Ajay, Schürer, Stephan C
Publicado 2018