Novel Anti-Cancer Agents and Cellular Targets and Their Mechanism(s) of Action

por Allison, Simon J.
Publicado 2022

RNA Interference by Single- and Double-stranded siRNA With a DNA Extension Containing a 3′ Nuclease-resistant Mini-hairpin Structure

por Allison, Simon J, Milner, Jo
Publicado 2014

Oncogenic viral protein HPV E7 up-regulates the SIRT1 longevity protein in human cervical cancer cells

por Allison, Simon J., Jiang, Ming, Milner, Jo
Publicado 2009

Active regulator of SIRT1 is required for cancer cell survival but not for SIRT1 activity

por Knight, John R. P., Allison, Simon J., Milner, Jo
Publicado 2013

The Warburg effect as a therapeutic target for bladder cancers and intratumoral heterogeneity in associated molecular targets

por Burns, Julie E., Hurst, Carolyn D., Knowles, Margaret A., Phillips, Roger M., Allison, Simon J.
Publicado 2021

Investigation of the cytotoxicity induced by didocosahexaenoin, an omega 3 derivative, in human prostate carcinoma cell lines

por Robinson, Glenn F., Sooda, Kartheek KY., Phillips, Roger M., Allison, Simon J., Javid, Farideh A.
Publicado 2022

Polysialic acid sustains cancer cell survival and migratory capacity in a hypoxic environment

por Elkashef, Sara M., Allison, Simon J., Sadiq, Maria, Basheer, Haneen A., Ribeiro Morais, Goreti, Loadman, Paul M., Pors, Klaus, Falconer, Robert A.
Publicado 2016

SIRT1 Undergoes Alternative Splicing in a Novel Auto-Regulatory Loop with p53

por Lynch, Cian J., Shah, Zahid H., Allison, Simon J., Ahmed, Shafiq U., Ford, Jack, Warnock, Lorna J., Li, Han, Serrano, Manuel, Milner, Jo
Publicado 2010

Anticancer metallohelices: nanomolar potency and high selectivity

por Kaner, Rebecca A., Allison, Simon J., Faulkner, Alan D., Phillips, Roger M., Roper, David I., Shepherd, Samantha L., Simpson, Daniel H., Waterfield, Nicholas R., Scott, Peter
Publicado 2016

Glycoconjugated Metallohelices have Improved Nuclear Delivery and Suppress Tumour Growth In Vivo

por Song, Hualong, Allison, Simon J., Brabec, Viktor, Bridgewater, Hannah E., Kasparkova, Jana, Kostrhunova, Hana, Novohradsky, Vojtech, Phillips, Roger M., Pracharova, Jitka, Rogers, Nicola J., Shepherd, Samantha L., Scott, Peter
Publicado 2020

Discovery of selective, antimetastatic and anti-cancer stem cell metallohelices via post-assembly modification

por Song, Hualong, Rogers, Nicola J., Allison, Simon J., Brabec, Viktor, Bridgewater, Hannah, Kostrhunova, Hana, Markova, Lenka, Phillips, Roger M., Pinder, Emma C., Shepherd, Samantha L., Young, Lawrence S., Zajac, Juraj, Scott, Peter
Publicado 2019

Self-assembly of an anion receptor with metal-dependent kinase inhibition and potent in vitro anti-cancer properties

por Allison, Simon J., Bryk, Jaroslaw, Clemett, Christopher J., Faulkner, Robert A., Ginger, Michael, Griffiths, Hollie B. S., Harmer, Jane, Jane Owen-Lynch, P., Pinder, Emma, Wurdak, Heiko, Phillips, Roger M., Rice, Craig R.
Publicado 2021

Development and characterization of a microfluidic model of the tumour microenvironment

por Ayuso, Jose M., Virumbrales-Muñoz, María, Lacueva, Alodia, Lanuza, Pilar M., Checa-Chavarria, Elisa, Botella, Pablo, Fernández, Eduardo, Doblare, Manuel, Allison, Simon J., Phillips, Roger M., Pardo, Julián, Fernandez, Luis J., Ochoa, Ignacio
Publicado 2016

Cross-species oncogenomics offers insight into human muscle-invasive bladder cancer

por Wong, Kim, Abascal, Federico, Ludwig, Latasha, Aupperle-Lellbach, Heike, Grassinger, Julia, Wright, Colin W., Allison, Simon J., Pinder, Emma, Phillips, Roger M., Romero, Laura P., Gal, Arnon, Roady, Patrick J., Pires, Isabel, Guscetti, Franco, Munday, John S., Peleteiro, Maria C., Pinto, Carlos A., Carvalho, Tânia, Cota, João, Du Plessis, Elizabeth C., Constantino-Casas, Fernando, Plog, Stephanie, Moe, Lars, de Brot, Simone, Bemelmans, Ingrid, Amorim, Renée Laufer, Georgy, Smitha R., Prada, Justina, del Pozo, Jorge, Heimann, Marianne, de Carvalho Nunes, Louisiane, Simola, Outi, Pazzi, Paolo, Steyl, Johan, Ubukata, Rodrigo, Vajdovich, Peter, Priestnall, Simon L., Suárez-Bonnet, Alejandro, Roperto, Franco, Millanta, Francesca, Palmieri, Chiara, Ortiz, Ana L., Barros, Claudio S. L., Gava, Aldo, Söderström, Minna E., O’Donnell, Marie, Klopfleisch, Robert, Manrique-Rincón, Andrea, Martincorena, Inigo, Ferreira, Ingrid, Arends, Mark J., Wood, Geoffrey A., Adams, David J., van der Weyden, Louise
Publicado 2023