Oxidative Stress in Tauopathies: From Cause to Therapy

por Bartolome, Fernando, Carro, Eva, Alquezar, Carolina
Publicado 2022

Tau Post-translational Modifications: Dynamic Transformers of Tau Function, Degradation, and Aggregation

por Alquezar, Carolina, Arya, Shruti, Kao, Aimee W.
Publicado 2021

Calmodulin levels in blood cells as a potential biomarker of Alzheimer’s disease

por Esteras, Noemí, Alquézar, Carolina, de la Encarnación, Ana, Villarejo, Alberto, Bermejo-Pareja, Félix, Martín-Requero, Ángeles
Publicado 2013

Inactivation of CDK/pRb Pathway Normalizes Survival Pattern of Lymphoblasts Expressing the FTLD-Progranulin Mutation c.709-1G>A

por Alquezar, Carolina, Esteras, Noemí, Alzualde, Ainhoa, Moreno, Fermín, Ayuso, Matilde S., López de Munain, Adolfo, Martín-Requero, Ángeles
Publicado 2012

Familial Alzheimer’s Disease Lymphocytes Respond Differently Than Sporadic Cells to Oxidative Stress: Upregulated p53-p21 Signaling Linked with Presenilin 1 Mutants

por Wojsiat, Joanna, Laskowska-Kaszub, Katarzyna, Alquézar, Carolina, Białopiotrowicz, Emilia, Esteras, Noemi, Zdioruk, Mykola, Martin-Requero, Angeles, Wojda, Urszula
Publicado 2016

Role of Resveratrol and Selenium on Oxidative Stress and Expression of Antioxidant and Anti-Aging Genes in Immortalized Lymphocytes from Alzheimer’s Disease Patients

por Cosín-Tomàs, Marta, Senserrich, Júlia, Arumí-Planas, Marta, Alquézar, Carolina, Pallàs, Mercè, Martín-Requero, Ángeles, Suñol, Cristina, Kaliman, Perla, Sanfeliu, Coral
Publicado 2019

Progranulin Deficiency Induces Mitochondrial Dysfunction in Frontotemporal Lobar Degeneration with TDP-43 Inclusions

por Rodríguez-Periñán, Guiomar, de la Encarnación, Ana, Moreno, Fermín, López de Munain, Adolfo, Martínez, Ana, Martín-Requero, Ángeles, Alquézar, Carolina, Bartolomé, Fernando
Publicado 2023

Heavy metals contaminating the environment of a progressive supranuclear palsy cluster induce tau accumulation and cell death in cultured neurons

por Alquezar, Carolina, Felix, Jessica B., McCandlish, Elizabeth, Buckley, Brian T., Caparros-Lefebvre, Dominique, Karch, Celeste M., Golbe, Lawrence I., Kao, Aimee W.
Publicado 2020

Targeting TDP-43 phosphorylation by Casein Kinase-1δ inhibitors: a novel strategy for the treatment of frontotemporal dementia

por Alquezar, Carolina, Salado, Irene G., de la Encarnación, Ana, Pérez, Daniel I., Moreno, Fermín, Gil, Carmen, de Munain, Adolfo López, Martínez, Ana, Martín-Requero, Ángeles
Publicado 2016

Phenotypic Screening Using High-Content Imaging to Identify Lysosomal pH Modulators in a Neuronal Cell Model

por Chin, Marcus Y., Ang, Kean-Hooi, Davies, Julia, Alquezar, Carolina, Garda, Virginia G., Rooney, Brendan, Leng, Kun, Kampmann, Martin, Arkin, Michelle R., Kao, Aimee W.
Publicado 2022

Genetically Encoded, pH-Sensitive mTFP1 Biosensor for Probing Lysosomal pH

por Chin, Marcus Y., Patwardhan, Anand R., Ang, Kean-Hooi, Wang, Austin L., Alquezar, Carolina, Welch, Mackenzie, Nguyen, Phi T., Grabe, Michael, Molofsky, Anna V., Arkin, Michelle R., Kao, Aimee W.
Publicado 2021

TSC1 loss increases risk for tauopathy by inducing tau acetylation and preventing tau clearance via chaperone-mediated autophagy

por Alquezar, Carolina, Schoch, Kathleen M., Geier, Ethan G., Ramos, Eliana Marisa, Scrivo, Aurora, Li, Kathy H., Argouarch, Andrea R., Mlynarski, Elisabeth E., Dombroski, Beth, DeTure, Michael, Dickson, Dennis W., Yokoyama, Jennifer S., Cuervo, Ana M., Burlingame, Alma L., Schellenberg, Gerard D., Miller, Timothy M., Miller, Bruce L., Kao, Aimee W.
Publicado 2021

Linking tuberous sclerosis complex, excessive mTOR signaling, and age-related neurodegeneration: a new association between TSC1 mutation and frontotemporal dementia

por Olney, Nicholas T., Alquezar, Carolina, Ramos, Eliana Marisa, Nana, Alissa L., Fong, Jamie C., Karydas, Anna M., Taylor, Joanne B., Stephens, Melanie L., Argouarch, Andrea R., Van Berlo, Victoria A., Dokuru, Deepika R., Sherr, Elliott H., Jicha, Gregory A., Dillon, William P., Desikan, Rahul S., De May, Mary, Seeley, William W., Coppola, Giovanni, Miller, Bruce L., Kao, Aimee W.
Publicado 2017