P341: L-ASPARAGINASE BY-PRODUCT GLUTAMATE IMPEDES THE EFFECT OF CHEMOTHERAPY BY AUGMENTING GLUTATHIONE BIOSYNTHESIS

por Hlozkova, Katerina, Vasylkivska, Maryna, Zwyrtkova, Martina, Kolarik, Matus, Potuckova, Eliska, Alquezar Artieda, Natividad, Zaliova, Marketa, Trka, Jan, Tennant, Daniel, Starkova, Julia
Publicado 2023

PTEN/PI3K/Akt pathway alters sensitivity of T-cell acute lymphoblastic leukemia to l-asparaginase

por Hlozkova, Katerina, Hermanova, Ivana, Safrhansova, Lucie, Alquezar-Artieda, Natividad, Kuzilkova, Daniela, Vavrova, Adela, Sperkova, Kristyna, Zaliova, Marketa, Stary, Jan, Trka, Jan, Starkova, Julia
Publicado 2022

Metabolic profile of leukemia cells influences treatment efficacy of L-asparaginase

por Hlozkova, Katerina, Pecinova, Alena, Alquezar-Artieda, Natividad, Pajuelo-Reguera, David, Simcikova, Marketa, Hovorkova, Lenka, Rejlova, Katerina, Zaliova, Marketa, Mracek, Tomas, Kolenova, Alexandra, Stary, Jan, Trka, Jan, Starkova, Julia
Publicado 2020

Chimeric JAK2 Kinases Trigger Non-uniform Changes of Cellular Metabolism in BCR-ABL1-like Childhood ALL

por Lukes, Julius, Potuckova, Eliska, Alquezar-Artieda, Natividad, Hermanova, Ivana, Kosanovic, Sladjana, Hlozkova, Katerina, Alberich Jorda, Meritxell, Zuna, Jan, Trka, Jan, Tennant, Daniel A., Stanulla, Martin, Zaliova, Marketa, Starkova, Julia
Publicado 2023

Restored biosynthetic pathways induced by MSCs serve as rescue mechanism in leukemia cells after L-asparaginase therapy

por Alquezar-Artieda, Natividad, Kuzilkova, Daniela, Roberts, Jennie, Hlozkova, Katerina, Pecinova, Alena, Pecina, Petr, Zwyrtkova, Martina, Potuckova, Eliska, Kavan, Daniel, Hermanova, Ivana, Zaliova, Marketa, Novak, Petr, Mracek, Tomas, Sramkova, Lucie, Tennant, Daniel A., Trka, Jan, Starkova, Julia
Publicado 2022