Design, Synthesis, and Biological Evaluation of 2-Mercaptobenzoxazole Derivatives as Potential Multi-Kinase Inhibitors

por Alanazi, Mohammed M., Aldawas, Saleh, Alsaif, Nawaf A.
Publicado 2023

A Comprehensive Investigation of Interactions between Antipsychotic Drug Quetiapine and Human Serum Albumin Using Multi-Spectroscopic, Biochemical, and Molecular Modeling Approache...

por Zargar, Seema, Wani, Tanveer A., Alsaif, Nawaf A., Khayyat, Arwa Ishaq A.
Publicado 2022

Antiproliferative Activity, Multikinase Inhibition, Apoptosis- Inducing Effects and Molecular Docking of Novel Isatin–Purine Hybrids

por Alanazi, Ashwag S., Mirgany, Tebyan O., Alsfouk, Aisha A., Alsaif, Nawaf A., Alanazi, Mohammed M.
Publicado 2023

Design, synthesis, antitumor evaluation, and molecular docking of novel pyrrolo[2,3-d]pyrimidine as multi-kinase inhibitors

por Alanazi, Ashwag S., Mirgany, Tebyan O., Alsaif, Nawaf A., Alsfouk, Aisha A., Alanazi, Mohammed M.
Publicado 2023

A validated LC-MS/MS analytical method for the quantification of pemigatinib: metabolic stability evaluation in human liver microsomes

por Attwa, Mohamed W., Abdelhameed, Ali S., Alsaif, Nawaf A., Kadi, Adnan A., AlRabiah, Haitham
Publicado 2022

Isolation, characterization, development and evaluation of phytoconstituent based formulation for diabetic neuropathy

por Pathak, Rashmi, Sachan, Neetu, Kabra, Atul, Alanazi, Ashwag S., Alanazi, Mohammed M., Alsaif, Nawaf A., Chandra, Phool
Publicado 2023

Mechanistic interaction study of 5,6-Dichloro-2-[2-(pyridin-2-yl)ethyl]isoindoline-1,3-dione with bovine serum albumin by spectroscopic and molecular docking approaches

por Alanazi, Mohammed M., Almehizia, Abdulrahman A., Bakheit, Ahmed H., Alsaif, Nawaf A., Alkahtani, Hamad M., Wani, Tanveer A.
Publicado 2019

Charge-Transfer Complex of Linifanib with 2,3-dichloro-3,5-dicyano-1,4-benzoquinone: Synthesis, Spectroscopic Characterization, Computational Molecular Modelling and Application in...

por Darwish, Ibrahim A, Khalil, Nasr Y, Alsaif, Nawaf A, Herqash, Rashed N, Sayed, Ahmed Y A, Abdel-Rahman, Hamdy M
Publicado 2021

Interaction Characterization of a Tyrosine Kinase Inhibitor Erlotinib with a Model Transport Protein in the Presence of Quercetin: A Drug–Protein and Drug–Drug Interaction Investig...

por Wani, Tanveer A., Alanazi, Mohammed M., Alsaif, Nawaf A., Bakheit, Ahmed H., Zargar, Seema, Alsalami, Ommalhasan Mohammed, Khan, Azmat Ali
Publicado 2022

Gastroprotective evaluation of Medicago sativa L. (Fabaceae) on diabetic rats

por Chandra, Phool, Kaleem, Mohammad, Sachan, Neetu, Pathak, Rashmi, Alanazi, Ashwag S., Alsaif, Nawaf A., Alsanea, Sary, Alsuwayt, Bader, Alanazi, Mohammed M., Kabra, Atul
Publicado 2023

Investigation of Novel Benzoxazole-Oxadiazole Derivatives as Effective Anti-Alzheimer’s Agents: In Vitro and In Silico Approaches

por Anwar, Saeed, Rehman, Wajid, Hussain, Rafaqat, Khan, Shoaib, Alanazi, Mohammed M., Alsaif, Nawaf A., Khan, Yousaf, Iqbal, Shahid, Naz, Adeela, Hashmi, Muhammad Ali
Publicado 2023

Novel sulindac derivatives: synthesis, characterisation, evaluation of antioxidant, analgesic, anti-inflammatory, ulcerogenic and COX-2 inhibition activity

por Bhat, Mashooq A., Al-Omar, Mohamed A., Alsaif, Nawaf A., Almehizia, Abdulrahman A., Naglah, Ahmed M., Razak, Suhail, Khan, Azmat Ali, Ashraf, Naeem Mahmood
Publicado 2020

Discovery of new VEGFR-2 inhibitors based on bis([1, 2, 4]triazolo)[4,3-a:3',4'-c]quinoxaline derivatives as anticancer agents and apoptosis inducers

por Alsaif, Nawaf A., Taghour, Mohammed S., Alanazi, Mohammed M., Obaidullah, Ahmad J., Al-Mehizia, Abdulrahman A., Alanazi, Manal M., Aldawas, Saleh, Elwan, Alaa, Elkady, Hazem
Publicado 2021

Design, synthesis, docking, ADMET studies, and anticancer evaluation of new 3-methylquinoxaline derivatives as VEGFR-2 inhibitors and apoptosis inducers

por Alanazi, Mohammed M., Eissa, Ibrahim H., Alsaif, Nawaf A., Obaidullah, Ahmad J., Alanazi, Wael A., Alasmari, Abdullah F., Albassam, Hussam, Elkady, Hazem, Elwan, Alaa
Publicado 2021

Network Pharmacology- and Molecular Docking-Based Identification of Potential Phytocompounds from Argyreia capitiformis in the Treatment of Inflammation

por Obaidullah, Ahmad J., Alanazi, Mohammed M., Alsaif, Nawaf A., Alanazi, Ashwag S., Albassam, Hussam, AZ, Alanazi, Alwassil, Osama I., Alqahtani, Ali M., Tareq, Abu Montakim
Publicado 2022

Immunoinformatics-guided design of a multi-epitope vaccine based on the structural proteins of severe acute respiratory syndrome coronavirus 2

por Obaidullah, Ahmad J., Alanazi, Mohammed M., Alsaif, Nawaf A., Albassam, Hussam, Almehizia, Abdulrahman A., Alqahtani, Ali M., Mahmud, Shafi, Sami, Saad Ahmed, Emran, Talha Bin
Publicado 2021

Discovery of new 3-methylquinoxalines as potential anti-cancer agents and apoptosis inducers targeting VEGFR-2: design, synthesis, and in silico studies

por Alanazi, Mohammed M., Alaa, Elwan, Alsaif, Nawaf A., Obaidullah, Ahmad J., Alkahtani, Hamad M., Al-Mehizia, Abdulrahman A., Alsubaie, Sultan M., Taghour, Mohammed S., Eissa, Ibrahim H.
Publicado 2021

New quinoxaline-based VEGFR-2 inhibitors: design, synthesis, and antiproliferative evaluation with in silico docking, ADMET, toxicity, and DFT studies

por Alanazi, Mohammed M., Elkady, Hazem, Alsaif, Nawaf A., Obaidullah, Ahmad J., Alkahtani, Hamad M., Alanazi, Manal M., Alharbi, Madhawi A., Eissa, Ibrahim H., Dahab, Mohammed A.
Publicado 2021

A New CDK2 Inhibitor with 3-Hydrazonoindolin-2-One Scaffold Endowed with Anti-Breast Cancer Activity: Design, Synthesis, Biological Evaluation, and In Silico Insights

por Al-Sanea, Mohammad M., Obaidullah, Ahmad J., Shaker, Mohamed E., Chilingaryan, Garri, Alanazi, Mohammed M., Alsaif, Nawaf A., Alkahtani, Hamad M., Alsubaie, Sultan A., Abdelgawad, Mohamed A.
Publicado 2021

Deeper Insights on Cnesmone javanica Blume Leaves Extract: Chemical Profiles, Biological Attributes, Network Pharmacology and Molecular Docking

por Obaidullah, Ahmad J., Alanazi, Mohammed M., Alsaif, Nawaf A., Mahdi, Wael A., Fantoukh, Omer I., Tareq, Abu Montakim, Sami, Saad Ahmed, Alqahtani, Ali M., Emran, Talha Bin
Publicado 2021