Antiseizure medications use during pregnancy and congenital malformations: A retrospective study in Saudi Arabia

por Alsfouk, Bshra A., Almarzouqi, Manal Rashed, Alsfouk, Aisha A., Alageel, Saleh, Alsemari, Abdulaziz
Publicado 2021

Patterns of antiseizure medication prescription in pregnancy and maternal complications in women with epilepsy: A retrospective study in Saudi Arabia

por Alsfouk, Bshra A., Almarzouqi, Manal Rashed, Alageel, Saleh, Alsfouk, Aisha A., Alsemari, Abdulaziz
Publicado 2022

Molecular Docking and Dynamic Simulation Revealed the Potential Inhibitory Activity of Opioid Compounds Targeting the Main Protease of SARS-CoV-2

por Mahmoud, Samaher S. A., Elkaeed, Eslam B., Alsfouk, Aisha A., Abdelhafez, Elshimaa M. N.
Publicado 2022

Antiproliferative Activity, Multikinase Inhibition, Apoptosis- Inducing Effects and Molecular Docking of Novel Isatin–Purine Hybrids

por Alanazi, Ashwag S., Mirgany, Tebyan O., Alsfouk, Aisha A., Alsaif, Nawaf A., Alanazi, Mohammed M.
Publicado 2023

Design, synthesis, antitumor evaluation, and molecular docking of novel pyrrolo[2,3-d]pyrimidine as multi-kinase inhibitors

por Alanazi, Ashwag S., Mirgany, Tebyan O., Alsaif, Nawaf A., Alsfouk, Aisha A., Alanazi, Mohammed M.
Publicado 2023

In Silico Screening of Semi-Synthesized Compounds as Potential Inhibitors for SARS-CoV-2 Papain-like Protease: Pharmacophoric Features, Molecular Docking, ADMET, Toxicity and DFT S...

por Alesawy, Mohamed S., Elkaeed, Eslam B., Alsfouk, Aisha A., Metwaly, Ahmed M., Eissa, Ibrahim H.
Publicado 2021

Synthesis and Biological Evaluation of Imadazo[1,2-a]pyrazines as Anticancer and Antiviral Agents through Inhibition of CDK9 and Human Coronavirus

por Alsfouk, Aisha A., Alshibl, Hanan M., Alsfouk, Bshra A., Altwaijry, Najla A., Al-Abdullah, Ebtehal S.
Publicado 2022

Discovery of Potential SARS-CoV-2 Papain-like Protease Natural Inhibitors Employing a Multi-Phase In Silico Approach

por Elkaeed, Eslam B., Metwaly, Ahmed M., Alesawy, Mohamed S., Saleh, Abdulrahman M., Alsfouk, Aisha A., Eissa, Ibrahim H.
Publicado 2022

In Silico Exploration of Potential Natural Inhibitors against SARS-Cov-2 nsp10

por Eissa, Ibrahim H., Khalifa, Mohamed M., Elkaeed, Eslam B., Hafez, Elsayed E., Alsfouk, Aisha A., Metwaly, Ahmed M.
Publicado 2021

New Imadazopyrazines with CDK9 Inhibitory Activity as Anticancer and Antiviral: Synthesis, In Silico, and In Vitro Evaluation Approaches

por Alsfouk, Aisha A., Alshibl, Hanan M., Altwaijry, Najla A., Alanazi, Ashwag, AlKamaly, Omkulthom, Sultan, Ahlam, Alsfouk, Bshra A.
Publicado 2023

Design, synthesis, docking, MD simulations, and anti-proliferative evaluation of thieno[2,3-d]pyrimidine derivatives as new EGFR inhibitors

por Sobh, Eman A., Dahab, Mohammed A., Elkaeed, Eslam B., Alsfouk, Aisha A., Ibrahim, Ibrahim M., Metwaly, Ahmed M., Eissa, Ibrahim H.
Publicado 2023

A Multistage In Silico Study of Natural Potential Inhibitors Targeting SARS-CoV-2 Main Protease

por Elkaeed, Eslam B., Eissa, Ibrahim H., Elkady, Hazem, Abdelalim, Ahmed, Alqaisi, Ahmad M., Alsfouk, Aisha A., Elwan, Alaa, Metwaly, Ahmed M.
Publicado 2022

New Anticancer Theobromine Derivative Targeting EGFR(WT) and EGFR(T790M): Design, Semi-Synthesis, In Silico, and In Vitro Anticancer Studies

por Elkaeed, Eslam B., Yousef, Reda G., Elkady, Hazem, Alsfouk, Aisha A., Husein, Dalal Z., Ibrahim, Ibrahim M., Metwaly, Ahmed M., Eissa, Ibrahim H.
Publicado 2022

Pimenta dioica (L.) Merr. Bioactive Constituents Exert Anti-SARS-CoV-2 and Anti-Inflammatory Activities: Molecular Docking and Dynamics, In Vitro, and In Vivo Studies

por El Gizawy, Heba A., Boshra, Sylvia A., Mostafa, Ahmed, Mahmoud, Sara H., Ismail, Muhammad I., Alsfouk, Aisha A., Taher, Azza T., Al-Karmalawy, Ahmed A.
Publicado 2021

Combined In Silico and Experimental Investigations of Resveratrol Encapsulation by Beta-Cyclodextrin

por Iskineyeva, Ainara, Fazylov, Serik, Bakirova, Ryszhan, Sarsenbekova, Akmaral, Pustolaikina, Irina, Seilkhanov, Olzhas, Alsfouk, Aisha A., Elkaeed, Eslam B., Eissa, Ibrahim H., Metwaly, Ahmed M.
Publicado 2022

The Discovery of Potential SARS-CoV-2 Natural Inhibitors among 4924 African Metabolites Targeting the Papain-like Protease: A Multi-Phase In Silico Approach

por Elkaeed, Eslam B., Khalifa, Mohamed M., Alsfouk, Bshra A., Alsfouk, Aisha A., El-Attar, Abdul-Aziz M. M., Eissa, Ibrahim H., Metwaly, Ahmed M.
Publicado 2022

Anticancer derivative of the natural alkaloid, theobromine, inhibiting EGFR protein: Computer-aided drug discovery approach

por Eissa, Ibrahim H., Yousef, Reda G., Elkaeed, Eslam B., Alsfouk, Aisha A., Husein, Dalal Z., Ibrahim, Ibrahim M., Alesawy, Mohamed S., Elkady, Hazem, Metwaly, Ahmed M.
Publicado 2023

Synthesis, DFT and molecular docking of novel (Z)-4-bromo-N-(4-butyl-3 (quinolin-3-yl)thiazol-2(3H)-ylidene)benzamide as elastase inhibitor

por Mustafa, Muhammad Naeem, Channar, Pervaiz Ali, Ejaz, Syeda Abida, Afzal, Saira, Aziz, Mubashir, Shamim, Tahira, Saeed, Aamer, Alsfouk, Aisha A., Ujan, Rabail, Abbas, Qamar, Hökelek, Tuncer
Publicado 2023

A Theobromine Derivative with Anticancer Properties Targeting VEGFR‐2: Semisynthesis, in silico and in vitro Studies

por Eissa, Ibrahim H., Yousef, Reda G., Elkady, Hazem, Elkaeed, Eslam B., Alsfouk, Aisha A., Husein, Dalal Z., Ibrahim, Ibrahim M., Radwan, Mohamed M., Metwaly, Ahmed M.
Publicado 2023

A New Anticancer Semisynthetic Theobromine Derivative Targeting EGFR Protein: CADDD Study

por Eissa, Ibrahim H., Yousef, Reda G., Elkady, Hazem, Alsfouk, Aisha A., Alsfouk, Bshra A., Husein, Dalal Z., Ibrahim, Ibrahim M., Elkaeed, Eslam B., Metwaly, Ahmed M.
Publicado 2023