Novel Molecular Challenges in Targeting Anaplastic Lymphoma Kinase in ALK-Expressing Human Cancers

por Alshareef, Abdulraheem
Publicado 2017

Clinico-Pathological Study of K-ras Mutations in Colorectal Tumors: A Single-Center Retrospective Study of 51 Patients in Madinah, Saudi Arabia

por Mulla, Nasser, Alshareef, Abdulraheem, Syed, Abdul Rahman, Al-Jahel, Majid
Publicado 2020

Gene Methylation and Silencing of WIF1 Is a Frequent Genetic Abnormality in Mantle Cell Lymphoma

por Alshareef, Abdulraheem, Peters, Anthea C., Gélébart, Pascal, Chen, Will, Lai, Raymond
Publicado 2021

High expression of β-catenin contributes to the crizotinib resistant phenotype in the stem-like cell population in neuroblastoma

por Alshareef, Abdulraheem, Gupta, Nidhi, Zhang, Hai-Feng, Wu, Chengsheng, Haque, Moinul, Lai, Raymond
Publicado 2017

Oxidative stress enhances tumorigenicity and stem-like features via the activation of the Wnt/β-catenin/MYC/Sox2 axis in ALK-positive anaplastic large-cell lymphoma

por Wu, Chengsheng, Gupta, Nidhi, Huang, Yung-Hsing, Zhang, Hai-Feng, Alshareef, Abdulraheem, Chow, Alexandra, Lai, Raymond
Publicado 2018

Phosphorylation of Sox2 at Threonine 116 is a Potential Marker to Identify a Subset of Breast Cancer Cells with High Tumorigenecity and Stem-Like Features

por Gupta, Nidhi, Gopal, Keshav, Wu, Chengsheng, Alshareef, Abdulraheem, Chow, Alexandra, Wu, Fang, Wang, Peng, Ye, Xiaoxia, Bigras, Gilbert, Lai, Raymond
Publicado 2018

Oxidative stress induces the acquisition of cancer stem-like phenotype in breast cancer detectable by using a Sox2 regulatory region-2 (SRR2) reporter

por Gopal, Keshav, Gupta, Nidhi, Zhang, Haifeng, Alshareef, Abdulraheem, Alqahtani, Hind, Bigras, Gilbert, Lewis, Jamie, Douglas, Donna, Kneteman, Norman, Lavasanifar, Afsaneh, Lai, Raymond
Publicado 2015

The use of cellular thermal shift assay (CETSA) to study Crizotinib resistance in ALK-expressing human cancers

por Alshareef, Abdulraheem, Zhang, Hai-Feng, Huang, Yung-Hsing, Wu, Chengsheng, Zhang, Jing Dong, Wang, Peng, El-Sehemy, Ahmed, Fares, Mohamed, Lai, Raymond
Publicado 2016

Loss of miR-200b promotes invasion via activating the Kindlin-2/integrin β1/AKT pathway in esophageal squamous cell carcinoma: An E-cadherin-independent mechanism

por Zhang, Hai-Feng, Alshareef, Abdulraheem, Wu, Chengsheng, Li, Shang, Jiao, Ji-Wei, Cao, Hui-Hui, Lai, Raymond, Xu, Li-Yan, Li, En-Min
Publicado 2015

Profiling gene promoter occupancy of Sox2 in two phenotypically distinct breast cancer cell subsets using chromatin immunoprecipitation and genome-wide promoter microarrays

por Jung, Karen, Wang, Peng, Gupta, Nidhi, Gopal, Keshav, Wu, Fang, Ye, Xiaoxia, Alshareef, Abdulraheem, Bigras, Gilbert, McMullen, Todd P, Abdulkarim, Bassam S, Lai, Raymond
Publicado 2014

A positive feedback loop involving the Wnt/β-catenin/MYC/Sox2 axis defines a highly tumorigenic cell subpopulation in ALK-positive anaplastic large cell lymphoma

por Wu, Chengsheng, Zhang, Hai-Feng, Gupta, Nidhi, Alshareef, Abdulraheem, Wang, Qian, Huang, Yung-Hsing, Lewis, Jamie T., Douglas, Donna N., Kneteman, Norman M., Lai, Raymond
Publicado 2016

High Myc expression and transcription activity underlies intra-tumoral heterogeneity in triple-negative breast cancer

por Gupta, Nidhi, Jung, Karen, Wu, Chengsheng, Alshareef, Abdulraheem, Alqahtani, Hind, Damaraju, Sambasivarao, Mackey, John R., Ghosh, Sunita, Sabri, Siham, Abdulkarim, Bassam S., Bigras, Gilbert, Lai, Raymond
Publicado 2017

Triple negative breast cancers comprise a highly tumorigenic cell subpopulation detectable by its high responsiveness to a Sox2 regulatory region 2 (SRR2) reporter

por Jung, Karen, Gupta, Nidhi, Wang, Peng, Lewis, Jamie T., Gopal, Keshav, Wu, Fang, Ye, Xiaoxia, Alshareef, Abdulraheem, Abdulkarim, Bassam S., Douglas, Donna N., Kneteman, Norman M., Lai, Raymond
Publicado 2015

Constitutive Activation of STAT3 in Myeloma Cells Cultured in a Three-Dimensional, Reconstructed Bone Marrow Model

por Huang, Yung-Hsing, Molavi, Ommoleila, Alshareef, Abdulraheem, Haque, Moinul, Wang, Qian, Chu, Michael P., Venner, Christopher P., Sandhu, Irwindeep, Peters, Anthea C., Lavasanifar, Afsaneh, Lai, Raymond
Publicado 2018

The absence of a novel intron 19-retaining ALK transcript (ALK-I19) and MYCN amplification correlates with an excellent clinical outcome in neuroblastoma patients

por Alshareef, Abdulraheem, Irwin, Meredith S., Gupta, Nidhi, Zhang, Hai-Feng, Haque, Moinul, Findlay, Scott D., Seong, Bo Kyung Alex, Lai, Justine, Rayis, Mohammed, Al-Dandan, Sadeq, Lai, Raymond
Publicado 2018

Failure to replicate the association of rare loss-of-function variants in type I IFN immunity genes with severe COVID-19

por Povysil, Gundula, Butler-Laporte, Guillaume, Shang, Ning, Weng, Chen, Khan, Atlas, Alaamery, Manal, Nakanishi, Tomoko, Zhou, Sirui, Forgetta, Vincenzo, Eveleigh, Robert, Bourgey, Mathieu, Aziz, Naveed, Jones, Steven, Knoppers, Bartha, Scherer, Stephen, Strug, Lisa, Lepage, Pierre, Ragoussis, Jiannis, Bourque, Guillaume, Alghamdi, Jahad, Aljawini, Nora, Albes, Nour, Al-Afghani, Hani M., Alghamdi, Bader, Almutair, Mansour, Mahmoud, Ebrahim Sabri, Safie, Leen Abu, Bardisy, Hadeel El, Al Harthi, Fawz S., Alshareef, Abdulraheem, Suliman, Bandar Ali, Alqahtani, Saleh, AlMalik, Abdulaziz, Alrashed, May M., Massadeh, Salam, Mooser, Vincent, Lathrop, Mark, Arabi, Yaseen, Mbarek, Hamdi, Saad, Chadi, Al-Muftah, Wadha, Badji, Radja, Al Thani, Asma, Ismail, Said I., Gharavi, Ali G., Abedalthagafi, Malak S., Richards, J Brent, Goldstein, David B., Kiryluk, Krzysztof
Publicado 2020