Glucose dysregulation and response to common anti-diabetic agents in the FATZO/Pco mouse

por Peterson, Richard G., Jackson, Charles Van, Zimmerman, Karen M., Alsina-Fernandez, Jorge, Michael, M. Dodson, Emmerson, Paul J., Coskun, Tamer
Publicado 2017

Characterization of Viral Insulin-Like Peptides Reveals Unique White Adipose Tissue Specific Characteristics

por Chrudinova, Martina, Francois, Moreau, Noh, Hye Lim, Panikova, Terezie, Zakova, Lenka, Friedline, Randall H, Alsina-Fernandez, Jorge, Kim, Jason K, Jiracek, Jiri, Kahn, Ronald C, Altindis, Emrah
Publicado 2021

Modified UCN2 peptide treatment improves skeletal muscle mass and function in mouse models of obesity‐induced insulin resistance

por Borg, Melissa L., Massart, Julie, De Castro Barbosa, Thais, Archilla‐Ortega, Adrià, Smith, Jonathon A.B., Lanner, Johanna T., Alsina‐Fernandez, Jorge, Yaden, Benjamin, Culver, Alexander E., Karlsson, Håkan K.R., Brozinick, Joseph T., Zierath, Juleen R.
Publicado 2021

Long-Acting and Selective Oxytocin Peptide Analogs Show Antidiabetic and Antiobesity Effects in Male Mice

por Snider, Brandy, Geiser, Andrea, Yu, Xiao-peng, Beebe, Emily Cathleen, Willency, Jill Amanda, Qing, Keyun, Guo, Lili, Lu, Jianliang, Wang, Xiaojun, Yang, Qian, Efanov, Alexander, Adams, Andrew Charles, Coskun, Tamer, Emmerson, Paul Joseph, Alsina-Fernandez, Jorge, Ai, Minrong
Publicado 2019

LY3298176, a novel dual GIP and GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus: From discovery to clinical proof of concept

por Coskun, Tamer, Sloop, Kyle W., Loghin, Corina, Alsina-Fernandez, Jorge, Urva, Shweta, Bokvist, Krister B., Cui, Xuewei, Briere, Daniel A., Cabrera, Over, Roell, William C., Kuchibhotla, Uma, Moyers, Julie S., Benson, Charles T., Gimeno, Ruth E., D'Alessio, David A., Haupt, Axel
Publicado 2018

GIPR Agonism Inhibits PYY-Induced Nausea-Like Behavior

por Samms, Ricardo J., Cosgrove, Richard, Snider, Brandy M., Furber, Ellen C., Droz, Brian A., Briere, Daniel A., Dunbar, James, Dogra, Mridula, Alsina-Fernandez, Jorge, Borner, Tito, De Jonghe, Bart C., Hayes, Matthew R., Coskun, Tamer, Sloop, Kyle W., Emmerson, Paul J., Ai, Minrong
Publicado 2022

GIP Receptor Agonism Attenuates GLP-1 Receptor Agonist–Induced Nausea and Emesis in Preclinical Models

por Borner, Tito, Geisler, Caroline E., Fortin, Samantha M., Cosgrove, Richard, Alsina-Fernandez, Jorge, Dogra, Mridula, Doebley, Sarah, Sanchez-Navarro, Marcos J., Leon, Rosa M., Gaisinsky, Jane, White, Arianna, Bamezai, Ankur, Ghidewon, Misgana Y., Grill, Harvey J., Crist, Richard C., Reiner, Benjamin C., Ai, Minrong, Samms, Ricardo J., De Jonghe, Bart C., Hayes, Matthew R.
Publicado 2021

Structural determinants of dual incretin receptor agonism by tirzepatide

por Sun, Bingfa, Willard, Francis S., Feng, Dan, Alsina-Fernandez, Jorge, Chen, Qi, Vieth, Michal, Ho, Joseph D., Showalter, Aaron D., Stutsman, Cynthia, Ding, Liyun, Suter, Todd M., Dunbar, James D., Carpenter, John W., Mohammed, Faiz Ahmad, Aihara, Eitaro, Brown, Robert A., Bueno, Ana B., Emmerson, Paul J., Moyers, Julie S., Kobilka, Tong Sun, Coghlan, Matthew P., Kobilka, Brian K., Sloop, Kyle W.
Publicado 2022