Slipknot or Crystallographic Error: A Computational Analysis of the Plasmodium falciparum DHFR Structural Folds

por Tata, Rolland B., Alsulami, Ali F., Sheik Amamuddy, Olivier, Blundell, Tom L., Tastan Bishop, Özlem
Publicado 2022

Understanding the impacts of missense mutations on structures and functions of human cancer-related genes: A preliminary computational analysis of the COSMIC Cancer Gene Census

por Malhotra, Sony, Alsulami, Ali F., Heiyun, Yang, Ochoa, Bernardo Montano, Jubb, Harry, Forbes, Simon, Blundell, Tom L.
Publicado 2019

The Molecular Organization of Human cGMP Specific Phosphodiesterase 6 (PDE6): Structural Implications of Somatic Mutations in Cancer and Retinitis Pigmentosa

por Maryam, Arooma, Vedithi, Sundeep Chaitanya, Khalid, Rana Rehan, Alsulami, Ali F., Torres, Pedro Henrique Monteiro, Siddiqi, Abdul Rauf, Blundell, Tom L.
Publicado 2019

COSMIC Cancer Gene Census 3D database: understanding the impacts of mutations on cancer targets

por Alsulami, Ali F, Torres, Pedro H M, Moghul, Ismail, Arif, Sheikh Mohammed, Chaplin, Amanda K, Vedithi, Sundeep Chaitanya, Blundell, Tom L
Publicado 2021

HARP: a database of structural impacts of systematic missense mutations in drug targets of Mycobacterium leprae

por Vedithi, Sundeep Chaitanya, Malhotra, Sony, Skwark, Marcin J., Munir, Asma, Acebrón-García-De-Eulate, Marta, Waman, Vaishali P, Alsulami, Ali, Ascher, David B, Blundell, Tom L
Publicado 2020

SARS-CoV-2 3D database: understanding the coronavirus proteome and evaluating possible drug targets

por Alsulami, Ali F, Thomas, Sherine E, Jamasb, Arian R, Beaudoin, Christopher A, Moghul, Ismail, Bannerman, Bridget, Copoiu, Liviu, Vedithi, Sundeep Chaitanya, Torres, Pedro, Blundell, Tom L
Publicado 2021

Predicted structural mimicry of spike receptor-binding motifs from highly pathogenic human coronaviruses

por Beaudoin, Christopher A., Jamasb, Arian R., Alsulami, Ali F., Copoiu, Liviu, van Tonder, Andries J., Hala, Sharif, Bannerman, Bridget P., Thomas, Sherine E., Vedithi, Sundeep Chaitanya, Torres, Pedro H.M., Blundell, Tom L.
Publicado 2021

Whole exome sequencing reveals NOTCH1 mutations in anaplastic large cell lymphoma and points to Notch both as a key pathway and a potential therapeutic target

por Larose, Hugo, Prokoph, Nina, Matthews, Jamie D., Schlederer, Michaela, Högler, Sandra, Alsulami, Ali F., Ducray, Stephen P., Nuglozeh, Edem, Fazaludeen, Mohammad Feroze, Elmouna, Ahmed, Ceccon, Monica, Mologni, Luca, Gambacorti-Passerini, Carlo, Hoefler, Gerald, Lobello, Cosimo, Pospisilova, Sarka, Janikova, Andrea, Woessmann, Wilhelm, Welk, Christine Damm-, Zimmermann, Mar tin, Fedorova, Alina, Malone, Andrea, Smith, Owen, Wasik, Mariusz, Inghirami, Giorgio, Lamant, Laurence, Blundell, Tom L., Klapper, Wolfram, Merkel, Olaf, Burke, G. A. Amos, Mian, Shahid, Ashankyty, Ibraheem, Kenner, Lukas, Turner, Suzanne D.
Publicado 2020