The Function of AID in Somatic Mutation and Class Switch Recombination: Upstream or Downstream of DNA Breaks

por Chua, Katrin F., Alt, Frederick W., Manis, John P.
Publicado 2002

Assembly of Productive T Cell Receptor δ Variable Region Genes Exhibits Allelic Inclusion

por Sleckman, Barry P., Khor, Bernard, Monroe, Robert, Alt, Frederick W.
Publicado 1998

Antigen-Independent Appearance of Recombination Activating Gene (Rag)-Positive Bone Marrow B Cells in the Spleens of Immunized Mice

por Gärtner, Frank, Alt, Frederick W., Monroe, Robert J., Seidl, Katherine J.
Publicado 2000

Sγ3 switch sequences function in place of endogenous Sγ1 to mediate antibody class switching

por Zarrin, Ali A., Goff, Peter H., Senger, Kate, Alt, Frederick W.
Publicado 2008

Activated Ras Signals Developmental Progression of Recombinase-activating Gene (RAG)-deficient Pro-B Lymphocytes

por Shaw, Albert C., Swat, Wojciech, Ferrini, Roger, Davidson, Laurie, Alt, Frederick W.
Publicado 1999

Fundamental Roles of Chromatin Loop Extrusion in Antibody Class Switching

por Zhang, Xuefei, Zhang, Yu, Ba, Zhaoqing, Kyritsis, Nia, Casellas, Rafael, Alt, Frederick W.
Publicado 2019

DNA-PKcs and Artemis function in the end-joining phase of immunoglobulin heavy chain class switch recombination

por Franco, Sonia, Murphy, Michael M., Li, Gang, Borjeson, Tiffany, Boboila, Cristian, Alt, Frederick W.
Publicado 2008

Long-range Oncogenic Activation of IgH/c-myc Translocations by the IgH 3’ Regulatory Region

por Gostissa, Monica, Yan, Catherine T., Bianco, Julia M., Cogné, Michel, Pinaud, Eric, Alt, Frederick W.
Publicado 2009

Physiological role of the 3′IgH CBEs super-anchor in antibody class switching

por Zhang, Xuefei, Yoon, Hye Suk, Chapdelaine-Williams, Aimee M., Kyritsis, Nia, Alt, Frederick W.
Publicado 2021

Commitment of Immature CD4(+)8(+) Thymocytes to the CD4 Lineage Requires CD3 Signaling but Does Not Require Expression of Clonotypic T Cell Receptor (TCR) Chains

por Suzuki, Harumi, Shinkai, Yoichi, Granger, Lawrence G., Alt, Frederick W., Love, Paul E., Singer, Alfred
Publicado 1997

The Eδ enhancer controls the generation of CD4(−)CD8(−) αβTCR-expressing T cells that can give rise to different lineages of αβ T cells

por Aifantis, Iannis, Bassing, Craig H., Garbe, Annette I., Sawai, Katie, Alt, Frederick W., von Boehmer, Harald
Publicado 2006

Título no disponible

por Aifantis, Iannis, Bassing, Craig H., Garbe, Annette I., Sawai, Katie, Alt, Frederick W., von Boehmer, Harald
Publicado 2006

Analysis of Mice Lacking DNaseI Hypersensitive Sites at the 5′ End of the IgH Locus

por Perlot, Thomas, Pawlitzky, Inka, Manis, John P., Zarrin, Ali A., Brodeur, Peter H., Alt, Frederick W.
Publicado 2010

Genome-wide detection of DNA double-stranded breaks induced by engineered nucleases

por Frock, Richard L., Hu, Jiazhi, Meyers, Robin M., Ho, Yu-Jui, Kii, Erina, Alt, Frederick W.
Publicado 2014

Orientation-specific RAG activity in chromosomal loop domains contributes to Tcrd V(D)J recombination during T cell development

por Zhao, Lijuan, Frock, Richard L., Du, Zhou, Hu, Jiazhi, Chen, Liang, Krangel, Michael S., Alt, Frederick W.
Publicado 2016

DNA melting initiates the RAG catalytic pathway

por Ru, Heng, Mi, Wei, Zhang, Pengfei, Alt, Frederick W., Schatz, David G., Liao, Maofu, Wu, Hao
Publicado 2018

Independent and Opposing Roles For Btk and Lyn in B and Myeloid Signaling Pathways

por Satterthwaite, Anne B., Lowell, Clifford A., Khan, Wasif N., Sideras, Paschalis, Alt, Frederick W., Witte, Owen N.
Publicado 1998

Polζ ablation in B cells impairs the germinal center reaction, class switch recombination, DNA break repair, and genome stability

por Schenten, Dominik, Kracker, Sven, Esposito, Gloria, Franco, Sonia, Klein, Ulf, Murphy, Michael, Alt, Frederick W., Rajewsky, Klaus
Publicado 2009

Deficiencies of GM-CSF and Interferon γ Link Inflammation and Cancer

por Enzler, Thomas, Gillessen, Silke, Manis, John P., Ferguson, David, Fleming, James, Alt, Frederick W., Mihm, Martin, Dranoff, Glenn
Publicado 2003

Ku70 Is Required for Late B Cell Development and Immunoglobulin Heavy Chain Class Switching

por Manis, John P., Gu, Yansong, Lansford, Rusty, Sonoda, Eiichiro, Ferrini, Roger, Davidson, Laurie, Rajewsky, Klaus, Alt, Frederick W.
Publicado 1998