Disordered structure and flexible roles: using the prion protein N1 fragment for neuroprotective and regenerative therapy

por Mohammadi, Behnam, Glatzel, Markus, Altmeppen, Hermann Clemens
Publicado 2020

Show Me Your Friends and I Tell You Who You Are: The Many Facets of Prion Protein in Stroke

por Puig, Berta, Yang, Denise, Brenna, Santra, Altmeppen, Hermann Clemens, Magnus, Tim
Publicado 2020

Brain-Derived Extracellular Vesicles in Health and Disease: A Methodological Perspective

por Brenna, Santra, Krisp, Christoph, Altmeppen, Hermann Clemens, Magnus, Tim, Puig, Berta
Publicado 2021

Cellular Composition of Cerebrospinal Fluid in HIV-1 Infected and Uninfected Subjects

por Ho, Emily L., Ronquillo, Rollie, Altmeppen, Hermann, Spudich, Serena S., Price, Richard W., Sinclair, Elizabeth
Publicado 2013

N-Glycans and Glycosylphosphatidylinositol-Anchor Act on Polarized Sorting of Mouse PrP(C) in Madin-Darby Canine Kidney Cells

por Puig, Berta, Altmeppen, Hermann C., Thurm, Dana, Geissen, Markus, Conrad, Catharina, Braulke, Thomas, Glatzel, Markus
Publicado 2011

Loss of Homeostatic Microglia Signature in Prion Diseases

por Wang, Yue, Hartmann, Kristin, Thies, Edda, Mohammadi, Behnam, Altmeppen, Hermann, Sepulveda-Falla, Diego, Glatzel, Markus, Krasemann, Susanne
Publicado 2022

Anchorless risk or released benefit? An updated view on the ADAM10-mediated shedding of the prion protein

por Mohammadi, Behnam, Song, Feizhi, Matamoros-Angles, Andreu, Shafiq, Mohsin, Damme, Markus, Puig, Berta, Glatzel, Markus, Altmeppen, Hermann Clemens
Publicado 2022

Inducing prion protein shedding as a neuroprotective and regenerative approach in pathological conditions of the brain: from theory to facts

por Matamoros-Angles, Andreu, Mohammadi, Behnam, Song, Feizhi, Shafiq, Mohsin, Brenna, Santra, Puig, Berta, Glatzel, Markus, Altmeppen, Hermann C.
Publicado 2023

Multiplexed mRNA analysis of brain-derived extracellular vesicles upon experimental stroke in mice reveals increased mRNA content with potential relevance to inflammation and recov...

por Bub, Annika, Brenna, Santra, Alawi, Malik, Kügler, Paul, Gui, Yuqi, Kretz, Oliver, Altmeppen, Hermann, Magnus, Tim, Puig, Berta
Publicado 2022

α-Synuclein conformers reveal link to clinical heterogeneity of α-synucleinopathies

por Schmitz, Matthias, Candelise, Niccolò, Canaslan, Sezgi, Altmeppen, Hermann C., Matschke, Jakob, Glatzel, Markus, Younas, Neelam, Zafar, Saima, Hermann, Peter, Zerr, Inga
Publicado 2023

Rapid and reliable universal cloning of influenza A virus genes by target-primed plasmid amplification

por Stech, Jürgen, Stech, Olga, Herwig, Astrid, Altmeppen, Hermann, Hundt, Jana, Gohrbandt, Sandra, Kreibich, Anne, Weber, Siegfried, Klenk, Hans-Dieter, Mettenleiter, Thomas C.
Publicado 2008

GPI-anchor signal sequence influences PrP(C) sorting, shedding and signalling, and impacts on different pathomechanistic aspects of prion disease in mice

por Puig, Berta, Altmeppen, Hermann C., Linsenmeier, Luise, Chakroun, Karima, Wegwitz, Florian, Piontek, Ulrike K., Tatzelt, Jörg, Bate, Clive, Magnus, Tim, Glatzel, Markus
Publicado 2019

Secretory pathway retention of mutant prion protein induces p38-MAPK activation and lethal disease in mice

por Puig, Berta, Altmeppen, Hermann C., Ulbrich, Sarah, Linsenmeier, Luise, Krasemann, Susanne, Chakroun, Karima, Acevedo-Morantes, Claudia Y., Wille, Holger, Tatzelt, Jörg, Glatzel, Markus
Publicado 2016

Prion protein oligomers cause neuronal cytoskeletal damage in rapidly progressive Alzheimer’s disease

por Shafiq, Mohsin, Zafar, Saima, Younas, Neelam, Noor, Aneeqa, Puig, Berta, Altmeppen, Hermann Clemens, Schmitz, Matthias, Matschke, Jakob, Ferrer, Isidre, Glatzel, Markus, Zerr, Inga
Publicado 2021

An optimized Western blot assay provides a comprehensive assessment of the physiological endoproteolytic processing of the prion protein

por Vanni, Ilaria, Iacobone, Floriana, D’Agostino, Claudia, Giovannelli, Matteo, Pirisinu, Laura, Altmeppen, Hermann Clemens, Castilla, Joaquin, Torres, Juan Maria, Agrimi, Umberto, Nonno, Romolo
Publicado 2022

Lack of a-disintegrin-and-metalloproteinase ADAM10 leads to intracellular accumulation and loss of shedding of the cellular prion protein in vivo

por Altmeppen, Hermann C, Prox, Johannes, Puig, Berta, Kluth, Mark A, Bernreuther, Christian, Thurm, Dana, Jorissen, Ellen, Petrowitz, Bettina, Bartsch, Udo, De Strooper, Bart, Saftig, Paul, Glatzel, Markus
Publicado 2011

Structural and mechanistic aspects influencing the ADAM10-mediated shedding of the prion protein

por Linsenmeier, Luise, Mohammadi, Behnam, Wetzel, Sebastian, Puig, Berta, Jackson, Walker S., Hartmann, Alexander, Uchiyama, Keiji, Sakaguchi, Suehiro, Endres, Kristina, Tatzelt, Jörg, Saftig, Paul, Glatzel, Markus, Altmeppen, Hermann C.
Publicado 2018

Characterization of brain-derived extracellular vesicles reveals changes in cellular origin after stroke and enrichment of the prion protein with a potential role in cellular uptak...

por Brenna, Santra, Altmeppen, Hermann C., Mohammadi, Behnam, Rissiek, Björn, Schlink, Florence, Ludewig, Peter, Krisp, Christoph, Schlüter, Hartmut, Failla, Antonio Virgilio, Schneider, Carola, Glatzel, Markus, Puig, Berta, Magnus, Tim
Publicado 2020

Generation of aggregation prone N-terminally truncated amyloid β peptides by meprin β depends on the sequence specificity at the cleavage site

por Schönherr, Caroline, Bien, Jessica, Isbert, Simone, Wichert, Rielana, Prox, Johannes, Altmeppen, Hermann, Kumar, Sathish, Walter, Jochen, Lichtenthaler, Stefan F., Weggen, Sascha, Glatzel, Markus, Becker-Pauly, Christoph, Pietrzik, Claus U.
Publicado 2016

Transgenic Overexpression of the Disordered Prion Protein N1 Fragment in Mice Does Not Protect Against Neurodegenerative Diseases Due to Impaired ER Translocation

por Mohammadi, Behnam, Linsenmeier, Luise, Shafiq, Mohsin, Puig, Berta, Galliciotti, Giovanna, Giudici, Camilla, Willem, Michael, Eden, Thomas, Koch-Nolte, Friedrich, Lin, Yu-Hsuan, Tatzelt, Jörg, Glatzel, Markus, Altmeppen, Hermann C.
Publicado 2020