Does Enhanced Structural Maturity of hiPSC-Cardiomyocytes Better for the Detection of Drug-Induced Cardiotoxicity?

por Van de Sande, Dieter, Ghasemi, Mohammadreza, Watters, Taylor, Burton, Francis, Pham, Ly, Altrocchi, Cristina, Gallacher, David J., Lu, Huarong, Smith, Godfrey
Publicado 2023

Repolarization instability and arrhythmia by I(Kr) block in single human-induced pluripotent stem cell-derived cardiomyocytes and 2D monolayers

por Altrocchi, Cristina, de Korte, Tessa, Bernardi, Joyce, Spätjens, Roel L H M G, Braam, Stefan R, Heijman, Jordi, Zaza, Antonio, Volders, Paul G A
Publicado 2020

High-Throughput Screening Assay for Detecting Drug-Induced Changes in Synchronized Neuronal Oscillations and Potential Seizure Risk Based on Ca(2+) Fluorescence Measurements in Hum...

por Lu, Hua-Rong, Seo, Manabu, Kreir, Mohamed, Tanaka, Tetsuya, Yamoto, Rie, Altrocchi, Cristina, van Ammel, Karel, Tekle, Fetene, Pham, Ly, Yao, Xiang, Teisman, Ard, Gallacher, David J.
Publicado 2023