Rate-of-Kill (RoK) assays to triage large compound sets for Chagas disease drug discovery: Application to GSK Chagas Box

por Cantizani, Juan, Gamallo, Pablo, Cotillo, Ignacio, Alvarez-Velilla, Raquel, Martin, Julio
Publicado 2021

Target-based vs. phenotypic screenings in Leishmania drug discovery: A marriage of convenience or a dialogue of the deaf?

por Reguera, Rosa M., Calvo-Álvarez, Estefanía, Álvarez-Velilla, Raquel, Balaña-Fouce, Rafael
Publicado 2014

Trypanosomatids topoisomerase re-visited. New structural findings and role in drug discovery

por Balaña-Fouce, Rafael, Álvarez-Velilla, Raquel, Fernández-Prada, Christopher, García-Estrada, Carlos, Reguera, Rosa M.
Publicado 2014

Synthesis of Marine α-Methoxylated Fatty Acid Analogs that Effectively Inhibit the Topoisomerase IB from Leishmania donovani with a Mechanism Different from that of Camptothecin

por Carballeira, Néstor M., Montano, Nashbly, Alvarez-Velilla, Raquel, Prada, Christopher F., Reguera, Rosa M., Balaña-Fouce, Rafael
Publicado 2013

Identification and Characterization of the Regions Involved in the Nuclear Translocation of the Heterodimeric Leishmanial DNA Topoisomerase IB

por Prada, Christopher F., Álvarez-Velilla, Raquel, Díaz-Gozález, Rosario, Pérez-Pertejo, Yolanda, Balaña-Fouce, Rafael, Reguera, Rosa M.
Publicado 2013

First Evidence of Intraclonal Genetic Exchange in Trypanosomatids Using Two Leishmania infantum Fluorescent Transgenic Clones

por Calvo-Álvarez, Estefanía, Álvarez-Velilla, Raquel, Jiménez, Maribel, Molina, Ricardo, Pérez-Pertejo, Yolanda, Balaña-Fouce, Rafael, Reguera, Rosa M.
Publicado 2014

Correction: First Evidence of Intraclonal Genetic Exchange in Trypanosomatids Using Two Leishmania infantum Fluorescent Transgenic Clones

por Calvo-Álvarez, Estefanía, Álvarez-Velilla, Raquel, Jiménez, Maribel, Molina, Ricardo, Pérez-Pertejo, Yolanda, Balaña-Fouce, Rafael, Reguera, Rosa M.
Publicado 2016

Topoisomerase IB poisons induce histone H2A phosphorylation as a response to DNA damage in Leishmania infantum

por Gutiérrez-Corbo, Camino, Álvarez-Velilla, Raquel, Reguera, Rosa M., García-Estrada, Carlos, Cushman, Mark, Balaña-Fouce, Rafael, Pérez-Pertejo, Yolanda
Publicado 2019

Antiparasitic effect of synthetic aromathecins on Leishmania infantum

por Reguera, Rosa M., Álvarez-Velilla, Raquel, Domínguez-Asenjo, Bárbara, Gutiérrez-Corbo, Camino, Balaña-Fouce, Rafael, Cushman, Mark, Pérez-Pertejo, Yolanda
Publicado 2019

A chronic bioluminescent model of experimental visceral leishmaniasis for accelerating drug discovery

por Álvarez-Velilla, Raquel, Gutiérrez-Corbo, Maria del Camino, Punzón, Carmen, Pérez-Pertejo, Maria Yolanda, Balaña-Fouce, Rafael, Fresno, Manuel, Reguera, Rosa María
Publicado 2019

Infrared Fluorescent Imaging as a Potent Tool for In Vitro, Ex Vivo and In Vivo Models of Visceral Leishmaniasis

por Calvo-Álvarez, Estefanía, Stamatakis, Kostantinos, Punzón, Carmen, Álvarez-Velilla, Raquel, Tejería, Ana, Escudero-Martínez, José Miguel, Pérez-Pertejo, Yolanda, Fresno, Manuel, Balaña-Fouce, Rafael, Reguera, Rosa M.
Publicado 2015

Appraisal of a Leishmania major Strain Stably Expressing mCherry Fluorescent Protein for Both In Vitro and In Vivo Studies of Potential Drugs and Vaccine against Cutaneous Leishman...

por Calvo-Álvarez, Estefania, Guerrero, Nestor Adrian, Álvarez-Velilla, Raquel, Prada, Christopher Fernández, Requena, Jose María, Punzón, Carmen, Llamas, Miguel Ángel, Arévalo, Francisco J., Rivas, Luis, Fresno, Manuel, Pérez-Pertejo, Yolanda, Balaña-Fouce, Rafael, Reguera, Rosa M.
Publicado 2012