PI3K Signaling in Mechanisms and Treatments of Pulmonary Fibrosis Following Sepsis and Acute Lung Injury

por Margaria, Jean Piero, Moretta, Lucia, Alves-Filho, Jose Carlos, Hirsch, Emilio
Publicado 2022

The critical role of heme oxygenase in neutrophil migration impairment in polymicrobial sepsis

por Freitas, Andressa, Alves-Filho, Jose Carlos, Suavinha, Marina Moreira, Spiller, Fernando, Dal-Secco, Daniela, Cunha, Fernando Queiroz
Publicado 2007

TLR2 signaling downregulates chemokine receptor CXCR2 and impairs neutrophil migration in severe polymicrobial sepsis

por Alves-Filho, Jose Carlos, Freitas, Andressa, Spiller, Fernando, Souto, Fabricio, Paula-Neto, Heitor, Silva, Joao Santana, Cunha, Fernando Queiroz
Publicado 2007

Reduction of gap junction proteins and intercalated disc structural remodeling in the hearts of mice submitted to sepsis

por Celes, Mara Rubia Nunes, Torrez-Dueñas, Diego, Alves-Filho, Jose Carlos, Duarte, Djane Braz, Cunha, Fernando Queiroz, Rossi, Marcos Antonio
Publicado 2007

Purinergic Cooperation Between P2Y(2) and P2X7 Receptors Promote Cutaneous Leishmaniasis Control: Involvement of Pannexin-1 and Leukotrienes

por Thorstenberg, Maria Luiza, Rangel Ferreira, Marcos Vinícius, Amorim, Natália, Canetti, Claudio, Morrone, Fernanda B., Alves Filho, José Carlos, Coutinho-Silva, Robson
Publicado 2018

Nitric oxide favours tumour-promoting inflammation through mitochondria-dependent and -independent actions on macrophages

por Drehmer, Daiana, Mesquita Luiz, João Paulo, Hernandez, Cesar Augusto Speck, Alves-Filho, José Carlos, Hussell, Tracy, Townsend, Paul Andrew, Moncada, Salvador
Publicado 2022

CCR4 Controls the Suppressive Effects of Regulatory T Cells on Early and Late Events during Severe Sepsis

por Molinaro, Raphael, Pecli, Cyntia, Guilherme, Rafael F., Alves-Filho, José Carlos, Cunha, Fernando Q., Canetti, Claudio, Kunkel, Steven L., Bozza, Marcelo T., Benjamim, Claudia F.
Publicado 2015

IL-33 signaling is essential to attenuate viral-induced encephalitis development by downregulating iNOS expression in the central nervous system

por Franca, Rafael F. O., Costa, Renata S., Silva, Jaqueline R., Peres, Raphael S., Mendonça, Leila R., Colón, David F., Alves-Filho, José Carlos, Cunha, Fernando Q.
Publicado 2016

CCR4-dependent reduction in the number and suppressor function of CD4(+)Foxp3(+) cells augments IFN-γ-mediated pulmonary inflammation and aggravates tuberculosis pathogenesis

por Bertolini, Thais B., Piñeros, Annie R., Prado, Rafael Q., Gembre, Ana Flávia, Ramalho, Leandra N. Z., Alves-Filho, José Carlos, Bonato, Vânia L. D.
Publicado 2018

TGFβ1 signaling sustains aryl hydrocarbon receptor (AHR) expression and restrains the pathogenic potential of T(H)17 cells by an AHR-independent mechanism

por de Lima, Kalil Alves, Donate, Paula Barbim, Talbot, Jhimmy, Davoli-Ferreira, Marcela, Peres, Raphael Sanches, Cunha, Thiago Mattar, Alves-Filho, José Carlos, Cunha, Fernando Queiroz
Publicado 2018

Peroxynitrite mediates neutrophil migration failure in severe polymicrobial sepsis

por Dal-Secco, Daniela, Torres-Dueñas, Diego, Freitas, Andressa, Celes, Mara Rubia Nunes, Alves-Filho, José Carlos, Spiller, Fernando, Dalto, Vitor Faeda, Rossi, Marcos Antonio, Ferreira, Sérgio Henrique, Cunha, Fernando Queiroz
Publicado 2007

Blockage of Eosinopoiesis by IL-17A Is Prevented by Cytokine and Lipid Mediators of Allergic Inflammation

por Xavier-Elsas, Pedro, de Luca, Bianca, Queto, Túlio, Vieira, Bruno Marques, Masid-de-Brito, Daniela, Dahab, Elizabeth Chen, Alves Filho, José Carlos, Cunha, Fernando Q., Gaspar-Elsas, Maria Ignez C.
Publicado 2015

STING regulates metabolic reprogramming in macrophages via HIF-1α during Brucella infection

por Gomes, Marco Tulio R., Guimarães, Erika S., Marinho, Fabio V., Macedo, Isabella, Aguiar, Eric R. G. R., Barber, Glen N., Moraes-Vieira, Pedro M. M., Alves-Filho, José Carlos, Oliveira, Sergio C.
Publicado 2021

Therapeutic Effects of Treatment with Anti-TLR2 and Anti-TLR4 Monoclonal Antibodies in Polymicrobial Sepsis

por Lima, Cristiano Xavier, Souza, Danielle Gloria, Amaral, Flavio Almeida, Fagundes, Caio Tavares, Rodrigues, Irla Paula Stopa, Alves-Filho, Jose Carlos, Kosco-Vilbois, Marie, Ferlin, Walter, Shang, Limin, Elson, Greg, Teixeira, Mauro Martins
Publicado 2015

Cardiovascular and Autonomic Dysfunction in Murine Ligature-Induced Periodontitis

por Ribeiro, Aline Barbosa, Santos-Junior, Nilton Nascimento, Luiz, João Paulo Mesquita, de Oliveira, Mauro, Kanashiro, Alexandre, Taira, Thaise Mayumi, Fukada, Sandra Yasuyo, Alves-Filho, José Carlos, Fazan Junior, Rubens, Salgado, Helio Cesar
Publicado 2020

Inhibition of Tryptophan Catabolism Is Associated With Neuroprotection During Zika Virus Infection

por Marim, Fernanda Martins, Teixeira, Danielle Cunha, Queiroz-Junior, Celso Martins, Valiate, Bruno Vinicius Santos, Alves-Filho, Jose Carlos, Cunha, Thiago Mattar, Dantzer, Robert, Teixeira, Mauro Martins, Teixeira, Antonio Lucio, Costa, Vivian Vasconcelos
Publicado 2021

Paradoxical Roles of the Neutrophil in Sepsis: Protective and Deleterious

por Sônego, Fabiane, Castanheira, Fernanda Vargas e Silva, Ferreira, Raphael Gomes, Kanashiro, Alexandre, Leite, Caio Abner Vitorino Gonçalves, Nascimento, Daniele Carvalho, Colón, David Fernando, Borges, Vanessa de Fátima, Alves-Filho, José Carlos, Cunha, Fernando Queiróz
Publicado 2016

IL-1α promotes liver inflammation and necrosis during blood-stage Plasmodium chabaudi malaria

por de Menezes, Maria Nogueira, Salles, Érika Machado, Vieira, Flávia, Amaral, Eduardo Pinheiro, Zuzarte-Luís, Vanessa, Cassado, Alexandra, Epiphanio, Sabrina, Alvarez, José Maria, Alves-Filho, José Carlos, Mota, Maria Manuel, D’Império-Lima, Maria Regina
Publicado 2019

NLRP3 Inflammasome and Mineralocorticoid Receptors Are Associated with Vascular Dysfunction in Type 2 Diabetes Mellitus

por Ferreira, Nathanne Santos, Bruder-Nascimento, Thiago, Pereira, Camila André, Zanotto, Camila Zillioto, Prado, Douglas Silva, Silva, Josiane Fernandes, Rassi, Diane Meyre, Foss-Freitas, Maria Cristina, Alves-Filho, Jose Carlos, Carlos, Daniela, Tostes, Rita de Cássia
Publicado 2019

STING is an intrinsic checkpoint inhibitor that restrains the T(H)17 cell pathogenic program

por Damasceno, Luis Eduardo Alves, Cebinelli, Guilherme Cesar Martelossi, Fernandes, Mariane Font, Nascimento, Daniele Carvalho, Públio, Gabriel Azevedo, Vinolo, Marco Aurélio Ramirez, Oliveira, Sergio Costa, Sparwasser, Tim, Cunha, Thiago Mattar, Cunha, Fernando Queiroz, Alves-Filho, José Carlos
Publicado 2022