Chemically Modified Peptide Scaffolds Target the CFTR-Associated Ligand PDZ Domain

por Amacher, Jeanine F., Zhao, Ruizhi, Spaller, Mark R., Madden, Dean R.
Publicado 2014

The Src module: an ancient scaffold in the evolution of cytoplasmic tyrosine kinases

por Shah, Neel H., Amacher, Jeanine F., Nocka, Laura M., Kuriyan, John
Publicado 2018

Specificity in PDZ-peptide interaction networks: Computational analysis and review

por Amacher, Jeanine F., Brooks, Lionel, Hampton, Thomas H., Madden, Dean R.
Publicado 2020

Saturation mutagenesis of a predicted ancestral Syk‐family kinase

por Hobbs, Helen T., Shah, Neel H., Shoemaker, Sophie R., Amacher, Jeanine F., Marqusee, Susan, Kuriyan, John
Publicado 2022

Domain Analysis and Motif Matcher (DAMM): A Program to Predict Selectivity Determinants in Monosiga brevicollis PDZ Domains Using Human PDZ Data

por Wofford, Haley A., Myers-Dean, Josh, Vogel, Brandon A., Alamo, Kevin Alexander Estrada, Longshore-Neate, Frederick A., Jagodzinski, Filip, Amacher, Jeanine F.
Publicado 2021

Sequence variation in the β7–β8 loop of bacterial class A sortase enzymes alters substrate selectivity

por Piper, Isabel M., Struyvenberg, Sarah A., Valgardson, Jordan D., Johnson, D. Alex, Gao, Melody, Johnston, Katherine, Svendsen, Justin E., Kodama, Hanna M., Hvorecny, Kelli L., Antos, John M., Amacher, Jeanine F.
Publicado 2021

Structures of Streptococcus pyogenes class A sortase in complex with substrate and product mimics provide key details of target recognition

por Johnson, D. Alex, Piper, Isabel M., Vogel, Brandon A., Jackson, Sophie N., Svendsen, Justin E., Kodama, Hanna M., Lee, Darren E., Lindblom, Katy M., McCarty, James, Antos, John M., Amacher, Jeanine F.
Publicado 2022

Additive energetic contributions of multiple peptide positions determine the relative promiscuity of viral and human sequences for PDZ domain targets

por Tahti, Elise F., Blount, Jadon M., Jackson, Sophie N., Gao, Melody, Gill, Nicholas P., Smith, Sarah N., Pederson, Nick J., Rumph, Simone N., Struyvenberg, Sarah A., Mackley, Iain G. P., Madden, Dean R., Amacher, Jeanine F.
Publicado 2023