Dissecting the tumor microenvironment of epigenetically driven gliomas: Opportunities for single-cell and spatial multiomics

por Sussman, Jonathan H, Xu, Jason, Amankulor, Nduka, Tan, Kai
Publicado 2023

The dominant TP53 hotspot mutation in IDH-mutant astrocytoma, R273C, has distinctive pathologic features and sex-specific prognostic implications

por Marker, Daniel F, Agnihotri, Sameer, Amankulor, Nduka, Murdoch, Geoffrey H, Pearce, Thomas M
Publicado 2021

Astrocyte-Specific Expression Patterns Associated with the PDGF-Induced Glioma Microenvironment

por Katz, Amanda M., Amankulor, Nduka M., Pitter, Ken, Helmy, Karim, Squatrito, Massimo, Holland, Eric C.
Publicado 2012

2036 Extracellular matrix as a novel approach to glioma therapy

por Murdock, Mark H., Chang, Jordan T., Hussey, George S., Amankulor, Nduka M., Engh, Johnathan A., Badylak, Stephen F.
Publicado 2018

The Subventricular Zone in Glioblastoma: Genesis, Maintenance, and Modeling

por Beiriger, Jamison, Habib, Ahmed, Jovanovich, Nicolina, Kodavali, Chowdari V., Edwards, Lincoln, Amankulor, Nduka, Zinn, Pascal O.
Publicado 2022

Percutaneous fixation for the treatment of metastatic spinal disease provides effective symptom palliation with low rates of hardware failure

por Jaman, Emade, Zhang, Xiaoran, Allen, Jordan, Saraiya, Raj G., Tollefson, Savannah, Hamilton, D. Kojo, Amankulor, Nduka M.
Publicado 2022

Elevated Na/H exchanger 1 (SLC9A1) emerges as a marker for tumorigenesis and prognosis in gliomas

por Guan, Xiudong, Luo, Lanxin, Begum, Gulnaz, Kohanbash, Gary, Song, Qingkun, Rao, Aparna, Amankulor, Nduka, Sun, Baoshan, Sun, Dandan, Jia, Wang
Publicado 2018

Tumor Bed Radiosurgery Following Resection and Prior Stereotactic Radiosurgery for Locally Persistent Brain Metastasis

por Holt, Douglas Emerson, Gill, Beant Singh, Clump, David Anthony, Leeman, Jonathan E., Burton, Steven A., Amankulor, Nduka M., Engh, Johnathan Anderson, Heron, Dwight E.
Publicado 2015

A liquid fraction of extracellular matrix inhibits glioma cell viability in vitro and in vivo

por Murdock, Mark H., Hussey, George S., Chang, Jordan T., Hill, Ryan C., Nascari, David G., Rao, Aparna V., Hansen, Kirk C., Foley, Lesley M., Hitchens, T. Kevin, Amankulor, Nduka M., Badylak, Stephen F.
Publicado 2022

Mutant IDH1 regulates the tumor-associated immune system in gliomas

por Amankulor, Nduka M., Kim, Youngmi, Arora, Sonali, Kargl, Julia, Szulzewsky, Frank, Hanke, Mark, Margineantu, Daciana H., Rao, Aparna, Bolouri, Hamid, Delrow, Jeff, Hockenbery, David, Houghton, A. McGarry, Holland, Eric C.
Publicado 2017

GBM-Targeted oHSV Armed with Matrix Metalloproteinase 9 Enhances Anti-tumor Activity and Animal Survival

por Sette, Paola, Amankulor, Nduka, Li, Aofei, Marzulli, Marco, Leronni, Daniela, Zhang, Mingdi, Goins, William F., Kaur, Balveen, Bolyard, Chelsea, Cripe, Timothy P., Yu, Jianhua, Chiocca, E. Antonio, Glorioso, Joseph C., Grandi, Paola
Publicado 2019

Targeting the translational machinery in gastrointestinal stromal tumors (GIST): a new therapeutic vulnerability

por Lee, Donna M., Sun, Angela, Patil, Sneha S., Liu, Lijun, Rao, Aparna V., Trent, Parker T., Ali, Areej A., Liu, Catherine, Rausch, Jessica L., Presutti, Laura D., Kaczorowski, Adam, Schneider, Felix, Amankulor, Nduka M., Shuda, Masahiro, Duensing, Anette
Publicado 2022

Single-cell profiling of human gliomas reveals macrophage ontogeny as a basis for regional differences in macrophage activation in the tumor microenvironment

por Müller, Sören, Kohanbash, Gary, Liu, S. John, Alvarado, Beatriz, Carrera, Diego, Bhaduri, Aparna, Watchmaker, Payal B., Yagnik, Garima, Di Lullo, Elizabeth, Malatesta, Martina, Amankulor, Nduka M., Kriegstein, Arnold R., Lim, Daniel A., Aghi, Manish, Okada, Hideho, Diaz, Aaron
Publicado 2017

TP53-PTEN-NF1 depletion in human brain organoids produces a glioma phenotype in vitro

por Singh, Sanjay K., Wang, Yan, Habib, Ahmed, Priyadarshini, Mamindla, Kodavali, Chowdari V., Chen, Apeng, Ma, Wencai, Wang, Jing, Hameed, N. U. Farrukh, Hu, Baoli, Fuller, Gregory N., Kulich, Scott M., Amankulor, Nduka, Colen, Rivka R., Edwards, Lincoln A., Zinn, Pascal O.
Publicado 2023

TIGIT and PD-1 Immune Checkpoint Pathways Are Associated With Patient Outcome and Anti-Tumor Immunity in Glioblastoma

por Raphael, Itay, Kumar, Rajeev, McCarl, Lauren H., Shoger, Karsen, Wang, Lin, Sandlesh, Poorva, Sneiderman, Chaim T., Allen, Jordan, Zhai, Shuyan, Campagna, Marissa Lynn, Foster, Alexandra, Bruno, Tullia C., Agnihotri, Sameer, Hu, Baoli, Castro, Brandyn A., Lieberman, Frank S., Broniscer, Alberto, Diaz, Aaron A., Amankulor, Nduka M., Rajasundaram, Dhivyaa, Pollack, Ian F., Kohanbash, Gary
Publicado 2021

Super-enhancer hijacking drives ectopic expression of hedgehog pathway ligands in meningiomas

por Youngblood, Mark W., Erson-Omay, Zeynep, Li, Chang, Najem, Hinda, Coșkun, Süleyman, Tyrtova, Evgeniya, Montejo, Julio D., Miyagishima, Danielle F., Barak, Tanyeri, Nishimura, Sayoko, Harmancı, Akdes Serin, Clark, Victoria E., Duran, Daniel, Huttner, Anita, Avşar, Timuçin, Bayri, Yasar, Schramm, Johannes, Boetto, Julien, Peyre, Matthieu, Riche, Maximilien, Goldbrunner, Roland, Amankulor, Nduka, Louvi, Angeliki, Bilgüvar, Kaya, Pamir, M. Necmettin, Özduman, Koray, Kilic, Türker, Knight, James R., Simon, Matthias, Horbinski, Craig, Kalamarides, Michel, Timmer, Marco, Heimberger, Amy B., Mishra-Gorur, Ketu, Moliterno, Jennifer, Yasuno, Katsuhito, Günel, Murat
Publicado 2023