A Structure- and Ligand-Based Virtual Screening of a Database of “Small” Marine Natural Products for the Identification of “Blue” Sigma-2 Receptor Ligands

por Floresta, Giuseppe, Amata, Emanuele, Barbaraci, Carla, Gentile, Davide, Turnaturi, Rita, Marrazzo, Agostino, Rescifina, Antonio
Publicado 2018

Morphing of Ibogaine: A Successful Attempt into the Search for Sigma-2 Receptor Ligands

por Floresta, Giuseppe, Dichiara, Maria, Gentile, Davide, Prezzavento, Orazio, Marrazzo, Agostino, Rescifina, Antonio, Amata, Emanuele
Publicado 2019

Sigma-2 receptor ligands QSAR model dataset

por Rescifina, Antonio, Floresta, Giuseppe, Marrazzo, Agostino, Parenti, Carmela, Prezzavento, Orazio, Nastasi, Giovanni, Dichiara, Maria, Amata, Emanuele
Publicado 2017

Synthesis and Structure-Activity Relationships of LP1 Derivatives: N-Methyl-N-phenylethylamino Analogues as Novel MOR Agonists

por Turnaturi, Rita, Parenti, Carmela, Prezzavento, Orazio, Marrazzo, Agostino, Pallaki, Paschalina, Georgoussi, Zafiroula, Amata, Emanuele, Pasquinucci, Lorella
Publicado 2018

Fourfold Filtered Statistical/Computational Approach for the Identification of Imidazole Compounds as HO-1 Inhibitors from Natural Products

por Floresta, Giuseppe, Amata, Emanuele, Gentile, Davide, Romeo, Giuseppe, Marrazzo, Agostino, Pittalà, Valeria, Salerno, Loredana, Rescifina, Antonio
Publicado 2019

Discovery and computational studies of piperidine/piperazine-based compounds endowed with sigma receptor affinity

por De Luca, Laura, Lombardo, Lisa, Mirabile, Salvatore, Marrazzo, Agostino, Dichiara, Maria, Cosentino, Giuseppe, Amata, Emanuele, Gitto, Rosaria
Publicado 2023

A Pseudouridine Isoxazolidinyl Nucleoside Analogue Structural Analysis: A Morphological Approach

por Floresta, Giuseppe, Pistarà, Venerando, Christensen, Kirsten E., Amata, Emanuele, Marrazzo, Agostino, Gentile, Davide, Rescifina, Antonio, Punzo, Francesco
Publicado 2018

C-5’-Triazolyl-2’-oxa-3’-aza-4’a-carbanucleosides: Synthesis and biological evaluation

por Romeo, Roberto, Carnovale, Caterina, Giofrè, Salvatore V, Chiacchio, Maria A, Garozzo, Adriana, Amata, Emanuele, Romeo, Giovanni, Chiacchio, Ugo
Publicado 2015

Cytotoxicity Profiles and Neuroprotective Properties of the Novel Ifenprodil Analogues as Sigma Ligands

por Zampieri, Daniele, Calabretti, Antonella, Romano, Maurizio, Fortuna, Sara, Collina, Simona, Amata, Emanuele, Dichiara, Maria, Marrazzo, Agostino, Mamolo, Maria Grazia
Publicado 2023

S2RSLDB: a comprehensive manually curated, internet-accessible database of the sigma-2 receptor selective ligands

por Nastasi, Giovanni, Miceli, Carla, Pittalà, Valeria, Modica, Maria N., Prezzavento, Orazio, Romeo, Giuseppe, Rescifina, Antonio, Marrazzo, Agostino, Amata, Emanuele
Publicado 2017

In vitro and in silico analysis of imatinib analogues as anti-Trypanosoma cruzi drug candidates

por Nesic de Freitas, Luca S. F., da Silva, Cristiane França, Intagliata, Sebastiano, Amata, Emanuele, Salerno, Loredana, Soeiro, Maria de Nazaré Correia
Publicado 2023

Synthesis and Structure-Activity Relationships of (−)-cis-N-Normetazocine-Based LP1 Derivatives

por Pasquinucci, Lorella, Parenti, Carmela, Amata, Emanuele, Georgoussi, Zafiroula, Pallaki, Paschalina, Camarda, Valeria, Calò, Girolamo, Arena, Emanuela, Montenegro, Lucia, Turnaturi, Rita
Publicado 2018

Comprehensive data on a 2D-QSAR model for Heme Oxygenase isoform 1 inhibitors

por Amata, Emanuele, Marrazzo, Agostino, Dichiara, Maria, Modica, Maria N., Salerno, Loredana, Prezzavento, Orazio, Nastasi, Giovanni, Rescifina, Antonio, Romeo, Giuseppe, Pittalà, Valeria
Publicado 2017

Novel N-normetazocine Derivatives with Opioid Agonist/Sigma-1 Receptor Antagonist Profile as Potential Analgesics in Inflammatory Pain

por Turnaturi, Rita, Chiechio, Santina, Pasquinucci, Lorella, Spoto, Salvatore, Costanzo, Giuliana, Dichiara, Maria, Piana, Silvia, Grasso, Margherita, Amata, Emanuele, Marrazzo, Agostino, Parenti, Carmela
Publicado 2022

Synthesis, Computational Insights, and Evaluation of Novel Sigma Receptors Ligands

por Dichiara, Maria, Ambrosio, Francesca Alessandra, Barbaraci, Carla, González-Cano, Rafael, Costa, Giosuè, Parenti, Carmela, Marrazzo, Agostino, Pasquinucci, Lorella, Cobos, Enrique J., Alcaro, Stefano, Amata, Emanuele
Publicado 2023

Combination of Heme Oxygenase-1 Inhibition and Sigma Receptor Modulation for Anticancer Activity

por Romeo, Giuseppe, Ciaffaglione, Valeria, Amata, Emanuele, Dichiara, Maria, Calabrese, Loredana, Vanella, Luca, Sorrenti, Valeria, Grosso, Salvo, D’Amico, Agata Grazia, D’Agata, Velia, Intagliata, Sebastiano, Salerno, Loredana
Publicado 2021

New Insights into the Opioid Analgesic Profile of cis-(−)-N-Normetazocine-derived Ligands

por Costanzo, Giuliana, Turnaturi, Rita, Parenti, Carmela, Spoto, Salvatore, Piana, Silvia, Dichiara, Maria, Zagni, Chiara, Galambos, Anna Rita, Essmat, Nariman, Marrazzo, Agostino, Amata, Emanuele, Al-Khrasani, Mahmoud, Pasquinucci, Lorella
Publicado 2023

Novel Structural Insight into Inhibitors of Heme Oxygenase-1 (HO-1) by New Imidazole-Based Compounds: Biochemical and In Vitro Anticancer Activity Evaluation

por Greish, Khaled F., Salerno, Loredana, Al Zahrani, Reem, Amata, Emanuele, Modica, Maria N., Romeo, Giuseppe, Marrazzo, Agostino, Prezzavento, Orazio, Sorrenti, Valeria, Rescifina, Antonio, Floresta, Giuseppe, Intagliata, Sebastiano, Pittalà, Valeria
Publicado 2018

Sigma-1 and Sigma-2 receptor ligands induce apoptosis and autophagy but have opposite effect on cell proliferation in uveal melanoma

por Longhitano, Lucia, Castracani, Carlo Castruccio, Tibullo, Daniele, Avola, Roberto, Viola, Maria, Russo, Giuliano, Prezzavento, Orazio, Marrazzo, Agostino, Amata, Emanuele, Reibaldi, Michele, Longo, Antonio, Russo, Andrea, Parrinello, Nunziatina Laura, Volti, Giovanni Li
Publicado 2017

Protozoan Parasite Growth Inhibitors Discovered by Cross-Screening Yield Potent Scaffolds for Lead Discovery

por Devine, William, Woodring, Jennifer L., Swaminathan, Uma, Amata, Emanuele, Patel, Gautam, Erath, Jessey, Roncal, Norma E., Lee, Patricia J., Leed, Susan E., Rodriguez, Ana, Mensa-Wilmot, Kojo, Sciotti, Richard J., Pollastri, Michael P.
Publicado 2015