Emerging nanotechnology-based therapeutics to combat multidrug-resistant cancer

por Yadav, Priya, Ambudkar, Suresh V., Rajendra Prasad, N.
Publicado 2022

New mechanisms of multidrug resistance: an introduction to the Cancer Drug Resistance special collection

por Gottesman, Michael M., Robey, Robert W., Ambudkar, Suresh V.
Publicado 2023

South Asian Medicinal Compounds as Modulators of Resistance to Chemotherapy and Radiotherapy

por Prasad, N. Rajendra, Muthusamy, Ganesan, Shanmugam, Mohana, Ambudkar, Suresh V.
Publicado 2016

Evidence for the critical role of transmembrane helices 1 and 7 in substrate transport by human P-glycoprotein (ABCB1)

por Sajid, Andaleeb, Lusvarghi, Sabrina, Chufan, Eduardo E., Ambudkar, Suresh V.
Publicado 2018

Pharmacophore Modeling of Nilotinib as an Inhibitor of ATP-Binding Cassette Drug Transporters and BCR-ABL Kinase Using a Three-Dimensional Quantitative Structure–Activity Relations...

por Shukla, Suneet, Kouanda, Abdul, Silverton, Latoya, Talele, Tanaji T., Ambudkar, Suresh V.
Publicado 2014

Multidrug transporters: recent insights from cryo-electron microscopy-derived atomic structures and animal models

por Lusvarghi, Sabrina, Robey, Robert W., Gottesman, Michael M., Ambudkar, Suresh V.
Publicado 2020

Use of photoimmunoconjugates to characterize ABCB1 in cancer cells

por Liang, Barry J., Lusvarghi, Sabrina, Ambudkar, Suresh V., Huang, Huang-Chiao
Publicado 2021

Mechanistic Insights into Photodynamic Regulation of Adenosine 5′-Triphosphate-Binding Cassette Drug Transporters

por Liang, Barry J., Lusvarghi, Sabrina, Ambudkar, Suresh V., Huang, Huang-Chiao
Publicado 2021

Plasma membrane calcium ATPase (PMCA4): A housekeeper for RT-PCR relative quantification of polytopic membrane proteins

por Calcagno, Anna Maria, Chewning, Katherine J, Wu, Chung-Pu, Ambudkar, Suresh V
Publicado 2006

Screening Compounds with a Novel High-Throughput ABCB1-Mediated Efflux Assay Identifies Drugs with Known Therapeutic Targets at Risk for Multidrug Resistance Interference

por Ansbro, Megan R., Shukla, Suneet, Ambudkar, Suresh V., Yuspa, Stuart H., Li, Luowei
Publicado 2013

Residues from Homologous Transmembrane Helices 4 and 10 Are Critical for P-Glycoprotein (ABCB1)-Mediated Drug Transport

por Rahman, Hadiar, Ware, Mark J., Sajid, Andaleeb, Lusvarghi, Sabrina, Durell, Stewart R., Ambudkar, Suresh V.
Publicado 2023

Characterization of the Lipidome and Biophysical Properties of Membranes from High Five Insect Cells Expressing Mouse P-Glycoprotein

por Moreno, Maria João, Teles Martins, Patrícia Alexandra, Bernardino, Eva F., Abel, Biebele, Ambudkar, Suresh V.
Publicado 2021

Brca1 breast tumors contain distinct CD44(+)/CD24(- )and CD133(+ )cells with cancer stem cell characteristics

por Wright, Mollie H, Calcagno, Anna Maria, Salcido, Crystal D, Carlson, Marisa D, Ambudkar, Suresh V, Varticovski, Lyuba
Publicado 2008

The FLT3 Inhibitor Quizartinib Inhibits ABCG2 at Pharmacologically Relevant Concentrations, with Implications for Both Chemosensitization and Adverse Drug Interactions

por Bhullar, Jasjeet, Natarajan, Karthika, Shukla, Suneet, Mathias, Trevor J., Sadowska, Mariola, Ambudkar, Suresh V., Baer, Maria R.
Publicado 2013

Mapping discontinuous epitopes for MRK-16, UIC2 and 4E3 antibodies to extracellular loops 1 and 4 of human P-glycoprotein

por Vahedi, Shahrooz, Lusvarghi, Sabrina, Pluchino, Kristen, Shafrir, Yinon, Durell, Stewart R., Gottesman, Michael M., Ambudkar, Suresh V.
Publicado 2018

Design, Synthesis and Biological Evaluation of Quinazolinamine Derivatives as Breast Cancer Resistance Protein and P-Glycoprotein Inhibitors with Improved Metabolic Stability

por Cai, Chao-Yun, Teng, Qiu-Xu, Murakami, Megumi, Ambudkar, Suresh V., Chen, Zhe-Sheng, Korlipara, Vijaya L.
Publicado 2023

Multiple Transport-Active Binding Sites Are Available for a Single Substrate on Human P-Glycoprotein (ABCB1)

por Chufan, Eduardo E., Kapoor, Khyati, Sim, Hong-May, Singh, Satyakam, Talele, Tanaji T., Durell, Stewart R., Ambudkar, Suresh V.
Publicado 2013

The Selective Class IIa Histone Deacetylase Inhibitor TMP195 Resensitizes ABCB1- and ABCG2-Overexpressing Multidrug-Resistant Cancer Cells to Cytotoxic Anticancer Drugs

por Wu, Chung-Pu, Lusvarghi, Sabrina, Wang, Jyun-Cheng, Hsiao, Sung-Han, Huang, Yang-Hui, Hung, Tai-Ho, Ambudkar, Suresh V.
Publicado 2019

Reversing the direction of drug transport mediated by the human multidrug transporter P-glycoprotein

por Sajid, Andaleeb, Lusvarghi, Sabrina, Murakami, Megumi, Chufan, Eduardo E., Abel, Biebele, Gottesman, Michael M., Durell, Stewart R., Ambudkar, Suresh V.
Publicado 2020

Nonsynonymous Mutations in Linker-2 of the Pdr5 Multidrug Transporter Identify a New RNA Stability Element

por Rahman, Hadiar, Rudrow, Andrew, Carneglia, Joshua, Joly, Sister Stephen Patrick, Nicotera, Dante, Naldrett, Michael, Choy, John, Ambudkar, Suresh V., Golin, John
Publicado 2019