mSphere of Influence: the Importance of Metabolism for Pathogen Adaptation to Host-Imposed Stresses

por Amich, Jorge
Publicado 2019

Sulfur Metabolism as a Promising Source of New Antifungal Targets

por Amich, Jorge
Publicado 2022

Deciphering metabolic traits of the fungal pathogen Aspergillus fumigatus: redundancy vs. essentiality

por Amich, Jorge, Krappmann, Sven
Publicado 2012

Factoring in the Complexity of the Cystic Fibrosis Lung to Understand Aspergillus fumigatus and Pseudomonas aeruginosa Interactions

por Beswick, Emily, Amich, Jorge, Gago, Sara
Publicado 2020

Editorial: Sulphur Metabolism of Fungi - Implications for Virulence and Opportunities for Therapy

por Amich, Jorge, Krappmann, Sven, Bachhawat, Anand Kumar
Publicado 2020

Regulation of Sulphur Assimilation Is Essential for Virulence and Affects Iron Homeostasis of the Human-Pathogenic Mould Aspergillus fumigatus

por Amich, Jorge, Schafferer, Lukas, Haas, Hubertus, Krappmann, Sven
Publicado 2013

The Transcription Factor ZafA Regulates the Homeostatic and Adaptive Response to Zinc Starvation in Aspergillus fumigatus

por Vicentefranqueira, Rocío, Amich, Jorge, Marín, Laura, Sánchez, Clara Inés, Leal, Fernando, Calera, José Antonio
Publicado 2018

Duox is the primary NADPH oxidase responsible for ROS production during adult caudal fin regeneration in zebrafish

por Chopra, Kunal, Folkmanaitė, Milda, Stockdale, Liam, Shathish, Vishali, Ishibashi, Shoko, Bergin, Rachel, Amich, Jorge, Amaya, Enrique
Publicado 2023

Histidine biosynthesis plays a crucial role in metal homeostasis and virulence of Aspergillus fumigatus

por Dietl, Anna-Maria, Amich, Jorge, Leal, Sixto, Beckmann, Nicola, Binder, Ulrike, Beilhack, Andreas, Pearlman, Eric, Haas, Hubertus
Publicado 2016

A Cyp51B Mutation Contributes to Azole Resistance in Aspergillus fumigatus

por Gonzalez-Jimenez, Irene, Lucio, Jose, Amich, Jorge, Cuesta, Isabel, Sanchez Arroyo, Rafael, Alcazar-Fuoli, Laura, Mellado, Emilia
Publicado 2020

The Caspofungin Paradoxical Effect is a Tolerant “Eagle Effect” in the Filamentous Fungal Pathogen Aspergillus fumigatus

por Valero, Clara, Colabardini, Ana Cristina, de Castro, Patrícia Alves, Amich, Jorge, Bromley, Michael J., Goldman, Gustavo H.
Publicado 2022

Targeting zinc homeostasis to combat Aspergillus fumigatus infections

por Vicentefranqueira, Rocío, Amich, Jorge, Laskaris, Paris, Ibrahim-Granet, Oumaima, Latgé, Jean P., Toledo, Héctor, Leal, Fernando, Calera, José A.
Publicado 2015

Dynamic Immune Cell Recruitment After Murine Pulmonary Aspergillus fumigatus Infection under Different Immunosuppressive Regimens

por Kalleda, Natarajaswamy, Amich, Jorge, Arslan, Berkan, Poreddy, Spoorthi, Mattenheimer, Katharina, Mokhtari, Zeinab, Einsele, Hermann, Brock, Matthias, Heinze, Katrin Gertrud, Beilhack, Andreas
Publicado 2016

Antagonism of the Azoles to Olorofim and Cross-Resistance Are Governed by Linked Transcriptional Networks in Aspergillus fumigatus

por van Rhijn, Norman, Hemmings, Sam, Storer, Isabelle S. R., Valero, Clara, Bin Shuraym, Hajer, Goldman, Gustavo H., Gsaller, Fabio, Amich, Jorge, Bromley, Michael J.
Publicado 2022

Potential Implication of Azole Persistence in the Treatment Failure of Two Haematological Patients Infected with Aspergillus fumigatus

por Peláez-García de la Rasilla, Teresa, Mato-López, Álvaro, Pablos-Puertas, Clara E., González-Huerta, Ana Julia, Gómez-López, Alicia, Mellado, Emilia, Amich, Jorge
Publicado 2023

Pseudomonas aeruginosa-Derived Volatile Sulfur Compounds Promote Distal Aspergillus fumigatus Growth and a Synergistic Pathogen-Pathogen Interaction That Increases Pathogenicity in...

por Scott, Jennifer, Sueiro-Olivares, Monica, Ahmed, Waqar, Heddergott, Christoph, Zhao, Can, Thomas, Riba, Bromley, Michael, Latgé, Jean-Paul, Krappmann, Sven, Fowler, Stephen, Bignell, Elaine, Amich, Jorge
Publicado 2019

Targeting Methionine Synthase in a Fungal Pathogen Causes a Metabolic Imbalance That Impacts Cell Energetics, Growth, and Virulence

por Scott, Jennifer, Sueiro-Olivares, Monica, Thornton, Benjamin P., Owens, Rebecca A., Muhamadali, Howbeer, Fortune-Grant, Rachael, Thomson, Darren, Thomas, Riba, Hollywood, Katherine, Doyle, Sean, Goodacre, Royston, Tabernero, Lydia, Bignell, Elaine, Amich, Jorge
Publicado 2020

Fungal and host protein persulfidation are functionally correlated and modulate both virulence and antifungal response

por Sueiro-Olivares, Monica, Scott, Jennifer, Gago, Sara, Petrovic, Dunja, Kouroussis, Emilia, Zivanovic, Jasmina, Yu, Yidong, Strobel, Marlene, Cunha, Cristina, Thomson, Darren, Fortune-Grant, Rachael, Thusek, Sina, Bowyer, Paul, Beilhack, Andreas, Carvalho, Agostinho, Bignell, Elaine, Filipovic, Milos R., Amich, Jorge
Publicado 2021

Aspergillus fumigatus Can Display Persistence to the Fungicidal Drug Voriconazole

por Scott, Jennifer, Valero, Clara, Mato-López, Álvaro, Donaldson, Ian J., Roldán, Alejandra, Chown, Harry, Van Rhijn, Norman, Lobo-Vega, Rebeca, Gago, Sara, Furukawa, Takanori, Morogovsky, Alma, Ben Ami, Ronen, Bowyer, Paul, Osherov, Nir, Fontaine, Thierry, Goldman, Gustavo H., Mellado, Emilia, Bromley, Michael, Amich, Jorge
Publicado 2023

Functional analysis of the Aspergillus fumigatus kinome reveals a DYRK kinase involved in septal plugging is a novel antifungal drug target

por van Rhijn, Norman, Zhao, Can, Al-Furaji, Narjes, Storer, Isabelle, Valero, Clara, Gago, Sara, Chown, Harry, Baldin, Clara, Fortune-Grant, Rachael, Shuraym, Hajer Bin, Ivanova, Lia, Kniemeyer, Olaf, Krüger, Thomas, Bignell, Elaine, Goldman, Gustavo, Amich, Jorge, Delneri, Daniela, Bowyer, Paul, Brakhage, Axel, Haas, Hubertus, Bromley, Michael
Publicado 2023