Characterisation and induction of tissue-resident gamma delta T-cells to target hepatocellular carcinoma

por Zakeri, Nekisa, Hall, Andrew, Swadling, Leo, Pallett, Laura J., Schmidt, Nathalie M., Diniz, Mariana O., Kucykowicz, Stephanie, Amin, Oliver E., Gander, Amir, Pinzani, Massimo, Davidson, Brian R., Quaglia, Alberto, Maini, Mala K.
Publicado 2022

Isolation of human intrahepatic leukocytes for phenotypic and functional characterization by flow cytometry

por Kucykowicz, Stephanie, Amin, Oliver E., Burton, Alice R., Swadling, Leo, Schmidt, Nathalie M., Zakeri, Nekisa, Davies, Jessica, Aidoo-Micah, Gloryanne, Stegmann, Kerstin A., Easom, Nicholas J., Jeffery-Smith, Anna, Maini, Mala K., Pallett, Laura J.
Publicado 2022

Circulating and intrahepatic antiviral B cells are defective in hepatitis B

por Burton, Alice R., Pallett, Laura J., McCoy, Laura E., Suveizdyte, Kornelija, Amin, Oliver E., Swadling, Leo, Alberts, Elena, Davidson, Brian R., Kennedy, Patrick T.F., Gill, Upkar S., Mauri, Claudia, Blair, Paul A., Pelletier, Nadege, Maini, Mala K.
Publicado 2018

Therapeutic Potential of TLR8 Agonist GS‐9688 (Selgantolimod) in Chronic Hepatitis B: Remodeling of Antiviral and Regulatory Mediators

por Amin, Oliver E., Colbeck, Emily J., Daffis, Stephane, Khan, Shahzada, Ramakrishnan, Dhivya, Pattabiraman, Divya, Chu, Ruth, Micolochick Steuer, Holly, Lehar, Sophie, Peiser, Leanne, Palazzo, Adam, Frey, Christian, Davies, Jessica, Javanbakht, Hassan, Rosenberg, William M.C., Fletcher, Simon P., Maini, Mala K., Pallett, Laura J.
Publicado 2021

Human Liver Memory CD8(+) T Cells Use Autophagy for Tissue Residence

por Swadling, Leo, Pallett, Laura J., Diniz, Mariana O., Baker, Josephine M., Amin, Oliver E., Stegmann, Kerstin A., Burton, Alice R., Schmidt, Nathalie M., Jeffery-Smith, Anna, Zakeri, Nekisa, Suveizdyte, Kornelija, Froghi, Farid, Fusai, Giuseppe, Rosenberg, William M., Davidson, Brian R., Schurich, Anna, Simon, A. Katharina, Maini, Mala K.
Publicado 2020

Longevity and replenishment of human liver-resident memory T cells and mononuclear phagocytes

por Pallett, Laura J., Burton, Alice R., Amin, Oliver E., Rodriguez-Tajes, Sergio, Patel, Amit A., Zakeri, Nekisa, Jeffery-Smith, Anna, Swadling, Leo, Schmidt, Nathalie M., Baiges, Anna, Gander, Amir, Yu, Dominic, Nasralla, David, Froghi, Farid, Iype, Satheesh, Davidson, Brian R., Thorburn, Douglas, Yona, Simon, Forns, Xavier, Maini, Mala K.
Publicado 2020

The human liver microenvironment shapes the homing and function of CD4(+) T-cell populations

por Wiggins, Benjamin G, Pallett, Laura J, Li, Xiaoyan, Davies, Scott P, Amin, Oliver E, Gill, Upkar S, Kucykowicz, Stephanie, Patel, Arzoo M, Aliazis, Konstantinos, Liu, Yuxin S, Reynolds, Gary M, Davidson, Brian R, Gander, Amir, Luong, Tu Vinh, Hirschfield, Gideon M, Kennedy, Patrick T F, Huang, Yuehua, Maini, Mala K, Stamataki, Zania
Publicado 2022

Targeting human Acyl-CoA:cholesterol acyltransferase as a dual viral and T cell metabolic checkpoint

por Schmidt, Nathalie M., Wing, Peter A. C., Diniz, Mariana O., Pallett, Laura J., Swadling, Leo, Harris, James M., Burton, Alice R., Jeffery-Smith, Anna, Zakeri, Nekisa, Amin, Oliver E., Kucykowicz, Stephanie, Heemskerk, Mirjam H., Davidson, Brian, Meyer, Tim, Grove, Joe, Stauss, Hans J., Pineda-Torra, Ines, Jolly, Clare, Jury, Elizabeth C., McKeating, Jane A., Maini, Mala K.
Publicado 2021

Pre-existing polymerase-specific T cells expand in abortive seronegative SARS-CoV-2

por Swadling, Leo, Diniz, Mariana O., Schmidt, Nathalie M., Amin, Oliver E., Chandran, Aneesh, Shaw, Emily, Pade, Corinna, Gibbons, Joseph M., Le Bert, Nina, Tan, Anthony T., Jeffery-Smith, Anna, Tan, Cedric C. S., Tham, Christine Y. L., Kucykowicz, Stephanie, Aidoo-Micah, Gloryanne, Rosenheim, Joshua, Davies, Jessica, Johnson, Marina, Jensen, Melanie P., Joy, George, McCoy, Laura E., Valdes, Ana M., Chain, Benjamin M., Goldblatt, David, Altmann, Daniel M., Boyton, Rosemary J., Manisty, Charlotte, Treibel, Thomas A., Moon, James C., van Dorp, Lucy, Balloux, Francois, McKnight, Áine, Noursadeghi, Mahdad, Bertoletti, Antonio, Maini, Mala K.
Publicado 2021

Discordant neutralizing antibody and T cell responses in asymptomatic and mild SARS-CoV-2 infection

por Reynolds, Catherine J., Swadling, Leo, Gibbons, Joseph M., Pade, Corinna, Jensen, Melanie P., Diniz, Mariana O., Schmidt, Nathalie M., Butler, David K., Amin, Oliver E., Bailey, Sasha N. L., Murray, Sam M., Pieper, Franziska P., Taylor, Stephen, Jones, Jessica, Jones, Meleri, Lee, Wing-Yiu Jason, Rosenheim, Joshua, Chandran, Aneesh, Joy, George, Di Genova, Cecilia, Temperton, Nigel, Lambourne, Jonathan, Cutino-Moguel, Teresa, Andiapen, Mervyn, Fontana, Marianna, Smit, Angelique, Semper, Amanda, O’Brien, Ben, Chain, Benjamin, Brooks, Tim, Manisty, Charlotte, Treibel, Thomas, Moon, James C., Noursadeghi, Mahdad, Altmann, Daniel M., Maini, Mala K., McKnight, Áine, Boyton, Rosemary J.
Publicado 2020

Immune boosting by B.1.1.529 (Omicron) depends on previous SARS-CoV-2 exposure

por Reynolds, Catherine J., Pade, Corinna, Gibbons, Joseph M., Otter, Ashley D., Lin, Kai-Min, Muñoz Sandoval, Diana, Pieper, Franziska P., Butler, David K., Liu, Siyi, Joy, George, Forooghi, Nasim, Treibel, Thomas A., Manisty, Charlotte, Moon, James C., Semper, Amanda, Brooks, Tim, McKnight, Áine, Altmann, Daniel M., Boyton, Rosemary J., Abbass, Hakam, Abiodun, Aderonke, Alfarih, Mashael, Alldis, Zoe, Altmann, Daniel M., Amin, Oliver E., Andiapen, Mervyn, Artico, Jessica, Augusto, João B., Baca, Georgina L., Bailey, Sasha N. L., Bhuva, Anish N., Boulter, Alex, Bowles, Ruth, Boyton, Rosemary J., Bracken, Olivia V., O’Brien, Ben, Brooks, Tim, Bullock, Natalie, Butler, David K., Captur, Gabriella, Carr, Olivia, Champion, Nicola, Chan, Carmen, Chandran, Aneesh, Coleman, Tom, Couto de Sousa, Jorge, Couto-Parada, Xose, Cross, Eleanor, Cutino-Moguel, Teresa, D’Arcangelo, Silvia, Davies, Rhodri H., Douglas, Brooke, Di Genova, Cecilia, Dieobi-Anene, Keenan, Diniz, Mariana O., Ellis, Anaya, Feehan, Karen, Finlay, Malcolm, Fontana, Marianna, Forooghi, Nasim, Francis, Sasha, Gibbons, Joseph M., Gillespie, David, Gilroy, Derek, Hamblin, Matt, Harker, Gabrielle, Hemingway, Georgia, Hewson, Jacqueline, Heywood, Wendy, Hickling, Lauren M., Hicks, Bethany, Hingorani, Aroon D., Howes, Lee, Itua, Ivie, Jardim, Victor, Lee, Wing-Yiu Jason, Jensen, Melaniepetra, Jones, Jessica, Jones, Meleri, Joy, George, Kapil, Vikas, Kelly, Caoimhe, Kurdi, Hibba, Lambourne, Jonathan, Lin, Kai-Min, Liu, Siyi, Lloyd, Aaron, Louth, Sarah, Maini, Mala K., Mandadapu, Vineela, Manisty, Charlotte, McKnight, Áine, Menacho, Katia, Mfuko, Celina, Mills, Kevin, Millward, Sebastian, Mitchelmore, Oliver, Moon, Christopher, Moon, James, Muñoz Sandoval, Diana, Murray, Sam M., Noursadeghi, Mahdad, Otter, Ashley, Pade, Corinna, Palma, Susana, Parker, Ruth, Patel, Kush, Pawarova, Mihaela, Petersen, Steffen E., Piniera, Brian, Pieper, Franziska P., Rannigan, Lisa, Rapala, Alicja, Reynolds, Catherine J., Richards, Amy, Robathan, Matthew, Rosenheim, Joshua, Rowe, Cathy, Royds, Matthew, Sackville West, Jane, Sambile, Genine, Schmidt, Nathalie M., Selman, Hannah, Semper, Amanda, Seraphim, Andreas, Simion, Mihaela, Smit, Angelique, Sugimoto, Michelle, Swadling, Leo, Taylor, Stephen, Temperton, Nigel, Thomas, Stephen, Thornton, George D., Treibel, Thomas A., Tucker, Art, Varghese, Ann, Veerapen, Jessry, Vijayakumar, Mohit, Warner, Tim, Welch, Sophie, White, Hannah, Wodehouse, Theresa, Wynne, Lucinda, Zahedi, Dan, Chain, Benjamin, Moon, James C.
Publicado 2022