Network and pathway expansion of genetic disease associations identifies successful drug targets

por MacNamara, Aidan, Nakic, Nikolina, Amin Al Olama, Ali, Guo, Cong, Sieber, Karsten B., Hurle, Mark R., Gutteridge, Alex
Publicado 2020

Influence of Genetic Variation in PDE3A on Endothelial Function and Stroke

por Traylor, Matthew, Amin Al Olama, Ali, Lyytikäinen, Leo-Pekka, Marini, Sandro, Chung, Jaeyoon, Malik, Rainer, Dichgans, Martin, Kähönen, Mika, Lehtimäki, Terho, Anderson, Christopher D., Raitakari, Olli T., Markus, Hugh S.
Publicado 2020

Simple MRI score aids prediction of dementia in cerebral small vessel disease

por Amin Al Olama, Ali, Wason, James M.S., Tuladhar, Anil M., van Leijsen, Esther M.C., Koini, Marisa, Hofer, Edith, Morris, Robin G., Schmidt, Reinhold, de Leeuw, Frank-Erik, Markus, Hugh S.
Publicado 2020

Implications of polygenic risk-stratified screening for prostate cancer on overdiagnosis

por Pashayan, Nora, Duffy, Stephen W., Neal, David E., Hamdy, Freddie C., Donovan, Jenny L., Martin, Richard M., Harrington, Patricia, Benlloch, Sara, Amin Al Olama, Ali, Shah, Mitul, Kote-Jarai, Zsofia, Easton, Douglas F., Eeles, Rosalind, Pharoah, Paul D.
Publicado 2015

Investigating the possible causal role of coffee consumption with prostate cancer risk and progression using Mendelian randomization analysis

por Taylor, Amy E., Martin, Richard M., Geybels, Milan S., Stanford, Janet L., Shui, Irene, Eeles, Rosalind, Easton, Doug, Kote‐Jarai, Zsofia, Amin Al Olama, Ali, Benlloch, Sara, Muir, Kenneth, Giles, Graham G, Wiklund, Fredrik, Gronberg, Henrik, Haiman, Christopher A, Schleutker, Johanna, Nordestgaard, Børge G., Travis, Ruth C, Neal, David, Pashayan, Nora, Khaw, Kay‐Tee, Blot, William, Thibodeau, Stephen, Maier, Christiane, Kibel, Adam S, Cybulski, Cezary, Cannon‐Albright, Lisa, Brenner, Hermann, Park, Jong, Kaneva, Radka, Batra, Jyotsna, Teixeira, Manuel R, Pandha, Hardev, Donovan, Jenny, Munafò, Marcus R.
Publicado 2016

A genome-wide association scan (GWAS) for mean telomere length within the COGS project: identified loci show little association with hormone-related cancer risk

por Pooley, Karen A., Bojesen, Stig E., Weischer, Maren, Nielsen, Sune F., Thompson, Deborah, Amin Al Olama, Ali, Michailidou, Kyriaki, Tyrer, Jonathan P., Benlloch, Sara, Brown, Judith, Audley, Tina, Luben, Robert, Khaw, K-T, Neal, David E., Hamdy, Freddie C., Donovan, Jenny L., Kote-Jarai, Zsofia, Baynes, Caroline, Shah, Mitul, Bolla, Manjeet K., Wang, Qin, Dennis, Joe, Dicks, Ed, Yang, Rongxi, Rudolph, Anja, Schildkraut, Joellen, Chang-Claude, Jenny, Burwinkel, Barbara, Chenevix-Trench, Georgia, Pharoah, Paul D. P., Berchuck, Andrew, Eeles, Rosalind A., Easton, Douglas F., Dunning, Alison M., Nordestgaard, Børge G.
Publicado 2013

Blood lipids and prostate cancer: a Mendelian randomization analysis

por Bull, Caroline J., Bonilla, Carolina, Holly, Jeff M. P., Perks, Claire M., Davies, Neil, Haycock, Philip, Yu, Oriana Hoi Yun, Richards, J. Brent, Eeles, Rosalind, Easton, Doug, Kote‐Jarai, Zsofia, Amin Al Olama, Ali, Benlloch, Sara, Muir, Kenneth, Giles, Graham G., MacInnis, Robert J., Wiklund, Fredrik, Gronberg, Henrik, Haiman, Christopher A., Schleutker, Johanna, Nordestgaard, Børge G., Travis, Ruth C., Neal, David, Pashayan, Nora, Khaw, Kay‐Tee, Stanford, Janet L., Blot, William J., Thibodeau, Stephen, Maier, Christiane, Kibel, Adam S., Cybulski, Cezary, Cannon‐Albright, Lisa, Brenner, Hermann, Park, Jong, Kaneva, Radka, Batra, Jyotsna, Teixeira, Manuel R., Micheal, Agnieszka, Pandha, Hardev, Smith, George Davey, Lewis, Sarah J., Martin, Richard M.
Publicado 2016

Genetic determinants of telomere length and risk of common cancers: a Mendelian randomization study

por Zhang, Chenan, Doherty, Jennifer A., Burgess, Stephen, Hung, Rayjean J., Lindström, Sara, Kraft, Peter, Gong, Jian, Amos, Christopher I., Sellers, Thomas A., Monteiro, Alvaro N.A., Chenevix-Trench, Georgia, Bickeböller, Heike, Risch, Angela, Brennan, Paul, Mckay, James D., Houlston, Richard S., Landi, Maria Teresa, Timofeeva, Maria N., Wang, Yufei, Heinrich, Joachim, Kote-Jarai, Zsofia, Eeles, Rosalind A., Muir, Ken, Wiklund, Fredrik, Grönberg, Henrik, Berndt, Sonja I., Chanock, Stephen J., Schumacher, Fredrick, Haiman, Christopher A., Henderson, Brian E., Amin Al Olama, Ali, Andrulis, Irene L., Hopper, John L., Chang-Claude, Jenny, John, Esther M., Malone, Kathleen E., Gammon, Marilie D., Ursin, Giske, Whittemore, Alice S., Hunter, David J., Gruber, Stephen B., Knight, Julia A., Hou, Lifang, Le Marchand, Loic, Newcomb, Polly A., Hudson, Thomas J., Chan, Andrew T., Li, Li, Woods, Michael O., Ahsan, Habibul, Pierce, Brandon L.
Publicado 2015

The effect of sample size on polygenic hazard models for prostate cancer

por Karunamuni, Roshan A., Huynh-Le, Minh-Phuong, Fan, Chun C., Eeles, Rosalind A., Easton, Douglas F., Kote-Jarai, ZSofia, Amin Al Olama, Ali, Benlloch Garcia, Sara, Muir, Kenneth, Gronberg, Henrik, Wiklund, Fredrik, Aly, Markus, Schleutker, Johanna, Sipeky, Csilla, Tammela, Teuvo L. J., Nordestgaard, Børge G., Key, Tim J., Travis, Ruth C., Neal, David E., Donovan, Jenny L., Hamdy, Freddie C., Pharoah, Paul, Pashayan, Nora, Khaw, Kay-Tee, Thibodeau, Stephen N., McDonnell, Shannon K., Schaid, Daniel J., Maier, Christiane, Vogel, Walther, Luedeke, Manuel, Herkommer, Kathleen, Kibel, Adam S., Cybulski, Cezary, Wokolorczyk, Dominika, Kluzniak, Wojciech, Cannon-Albright, Lisa, Brenner, Hermann, Schöttker, Ben, Holleczek, Bernd, Park, Jong Y., Sellers, Thomas A., Lin, Hui-Yi, Slavov, Chavdar, Kaneva, Radka, Mitev, Vanio, Batra, Jyotsna, Clements, Judith A., Spurdle, Amanda, Teixeira, Manuel R., Paulo, Paula, Maia, Sofia, Pandha, Hardev, Michael, Agnieszka, Mills, Ian G., Andreassen, Ole A., Dale, Anders M., Seibert, Tyler M.
Publicado 2020

Multiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among Europeans

por Amin Al Olama, Ali, Dadaev, Tokhir, Hazelett, Dennis J., Li, Qiuyan, Leongamornlert, Daniel, Saunders, Edward J., Stephens, Sarah, Cieza-Borrella, Clara, Whitmore, Ian, Benlloch Garcia, Sara, Giles, Graham G., Southey, Melissa C., Fitzgerald, Liesel, Gronberg, Henrik, Wiklund, Fredrik, Aly, Markus, Henderson, Brian E., Schumacher, Fredrick, Haiman, Christopher A., Schleutker, Johanna, Wahlfors, Tiina, Tammela, Teuvo L., Nordestgaard, Børge G., Key, Tim J., Travis, Ruth C., Neal, David E., Donovan, Jenny L., Hamdy, Freddie C., Pharoah, Paul, Pashayan, Nora, Khaw, Kay-Tee, Stanford, Janet L., Thibodeau, Stephen N., Mcdonnell, Shannon K., Schaid, Daniel J., Maier, Christiane, Vogel, Walther, Luedeke, Manuel, Herkommer, Kathleen, Kibel, Adam S., Cybulski, Cezary, Wokołorczyk, Dominika, Kluzniak, Wojciech, Cannon-Albright, Lisa, Brenner, Hermann, Butterbach, Katja, Arndt, Volker, Park, Jong Y., Sellers, Thomas, Lin, Hui-Yi, Slavov, Chavdar, Kaneva, Radka, Mitev, Vanio, Batra, Jyotsna, Clements, Judith A., Spurdle, Amanda, Teixeira, Manuel R., Paulo, Paula, Maia, Sofia, Pandha, Hardev, Michael, Agnieszka, Kierzek, Andrzej, Govindasami, Koveela, Guy, Michelle, Lophatonanon, Artitaya, Muir, Kenneth, Viñuela, Ana, Brown, Andrew A., Freedman, Mathew, Conti, David V., Easton, Douglas, Coetzee, Gerhard A., Eeles, Rosalind A., Kote-Jarai, Zsofia
Publicado 2015

Prediction of Breast and Prostate Cancer Risks in Male BRCA1 and BRCA2 Mutation Carriers Using Polygenic Risk Scores

por Lecarpentier, Julie, Silvestri, Valentina, Kuchenbaecker, Karoline B., Barrowdale, Daniel, Dennis, Joe, McGuffog, Lesley, Soucy, Penny, Leslie, Goska, Rizzolo, Piera, Navazio, Anna Sara, Valentini, Virginia, Zelli, Veronica, Lee, Andrew, Amin Al Olama, Ali, Tyrer, Jonathan P., Southey, Melissa, John, Esther M., Conner, Thomas A., Goldgar, David E., Buys, Saundra S., Janavicius, Ramunas, Steele, Linda, Ding, Yuan Chun, Neuhausen, Susan L., Hansen, Thomas V.O., Osorio, Ana, Weitzel, Jeffrey N., Toss, Angela, Medici, Veronica, Cortesi, Laura, Zanna, Ines, Palli, Domenico, Radice, Paolo, Manoukian, Siranoush, Peissel, Bernard, Azzollini, Jacopo, Viel, Alessandra, Cini, Giulia, Damante, Giuseppe, Tommasi, Stefania, Peterlongo, Paolo, Fostira, Florentia, Hamann, Ute, Evans, D. Gareth, Henderson, Alex, Brewer, Carole, Eccles, Diana, Cook, Jackie, Ong, Kai-ren, Walker, Lisa, Side, Lucy E., Porteous, Mary E., Davidson, Rosemarie, Hodgson, Shirley, Frost, Debra, Adlard, Julian, Izatt, Louise, Eeles, Ros, Ellis, Steve, Tischkowitz, Marc, Godwin, Andrew K., Meindl, Alfons, Gehrig, Andrea, Dworniczak, Bernd, Sutter, Christian, Engel, Christoph, Niederacher, Dieter, Steinemann, Doris, Hahnen, Eric, Hauke, Jan, Rhiem, Kerstin, Kast, Karin, Arnold, Norbert, Ditsch, Nina, Wang-Gohrke, Shan, Wappenschmidt, Barbara, Wand, Dorothea, Lasset, Christine, Stoppa-Lyonnet, Dominique, Belotti, Muriel, Damiola, Francesca, Barjhoux, Laure, Mazoyer, Sylvie, Van Heetvelde, Mattias, Poppe, Bruce, De Leeneer, Kim, Claes, Kathleen B.M., de la Hoya, Miguel, Garcia-Barberan, Vanesa, Caldes, Trinidad, Perez Segura, Pedro, Kiiski, Johanna I., Aittomäki, Kristiina, Khan, Sofia, Nevanlinna, Heli, van Asperen, Christi J., Vaszko, Tibor, Kasler, Miklos, Olah, Edith, Balmaña, Judith, Gutiérrez-Enríquez, Sara, Diez, Orland, Teulé, Alex, Izquierdo, Angel, Darder, Esther, Brunet, Joan, Del Valle, Jesús, Feliubadalo, Lidia, Pujana, Miquel Angel, Lazaro, Conxi, Arason, Adalgeir, Agnarsson, Bjarni A., Johannsson, Oskar Th., Barkardottir, Rosa B., Alducci, Elisa, Tognazzo, Silvia, Montagna, Marco, Teixeira, Manuel R., Pinto, Pedro, Spurdle, Amanda B., Holland, Helene, Lee, Jong Won, Lee, Min Hyuk, Lee, Jihyoun, Kim, Sung-Won, Kang, Eunyoung, Kim, Zisun, Sharma, Priyanka, Rebbeck, Timothy R., Vijai, Joseph, Robson, Mark, Lincoln, Anne, Musinsky, Jacob, Gaddam, Pragna, Tan, Yen Y., Berger, Andreas, Singer, Christian F., Loud, Jennifer T., Greene, Mark H., Mulligan, Anna Marie, Glendon, Gord, Andrulis, Irene L., Toland, Amanda Ewart, Senter, Leigha, Bojesen, Anders, Nielsen, Henriette Roed, Skytte, Anne-Bine, Sunde, Lone, Jensen, Uffe Birk, Pedersen, Inge Sokilde, Krogh, Lotte, Kruse, Torben A., Caligo, Maria A., Yoon, Sook-Yee, Teo, Soo-Hwang, von Wachenfeldt, Anna, Huo, Dezheng, Nielsen, Sarah M., Olopade, Olufunmilayo I., Nathanson, Katherine L., Domchek, Susan M., Lorenchick, Christa, Jankowitz, Rachel C., Campbell, Ian, James, Paul, Mitchell, Gillian, Orr, Nick, Park, Sue Kyung, Thomassen, Mads, Offit, Kenneth, Couch, Fergus J., Simard, Jacques, Easton, Douglas F., Chenevix-Trench, Georgia, Schmutzler, Rita K., Antoniou, Antonis C., Ottini, Laura
Publicado 2017