Pancreatic Cancer Genetics

por Amundadottir, Laufey T.
Publicado 2016

Artificial intelligence and improved early detection for pancreatic cancer

por Zhong, Jun, Shi, Jianxin, Amundadottir, Laufey T.
Publicado 2023

Master regulator activity QTL protocol to implicate regulatory pathways potentially mediating GWAS signals using eQTL data

por Hoskins, Jason W., Christensen, Trevor A., Amundadottir, Laufey T.
Publicado 2023

Characterization of SNPs Associated with Prostate Cancer in Men of Ashkenazic Descent from the Set of GWAS Identified SNPs: Impact of Cancer Family History and Cumulative SNP Risk...

por Agalliu, Ilir, Wang, Zhaoming, Wang, Tao, Dunn, Anne, Parikh, Hemang, Myers, Timothy, Burk, Robert D., Amundadottir, Laufey
Publicado 2013

Inferred expression regulator activities suggest genes mediating cardiometabolic genetic signals

por Hoskins, Jason W., Chung, Charles C., O’Brien, Aidan, Zhong, Jun, Connelly, Katelyn, Collins, Irene, Shi, Jianxin, Amundadottir, Laufey T.
Publicado 2021

The risk allele of SNP rs3803662 and the mRNA level of its closest genes TOX3 and LOC643714 predict adverse outcome for breast cancer patients

por Gudmundsdottir, Eydis Th, Barkardottir, Rosa B, Arason, Adalgeir, Gunnarsson, Haukur, Amundadottir, Laufey Th, Agnarsson, Bjarni A, Johannsson, Oskar Th, Reynisdottir, Inga
Publicado 2012

Cancer as a Complex Phenotype: Pattern of Cancer Distribution within and beyond the Nuclear Family

por Amundadottir, Laufey T, Thorvaldsson, Sverrir, Gudbjartsson, Daniel F, Sulem, Patrick, Kristjansson, Kristleifur, Arnason, Sigurdur, Gulcher, Jeffrey R, Bjornsson, Johannes, Kong, Augustine, Thorsteinsdottir, Unnur, Stefansson, Kari
Publicado 2004

An integrated transcriptome and epigenome analysis identifies a novel candidate gene for pancreatic cancer

por Jia, Jinping, Parikh, Hemang, Xiao, Wenming, Hoskins, Jason W, Pflicke, Holger, Liu, Xuelu, Collins, Irene, Zhou, Weiyin, Wang, Zhaoming, Powell, John, Thorgeirsson, Snorri S, Rudloff, Udo, Petersen, Gloria M, Amundadottir, Laufey T
Publicado 2013

Prospective study of DNA methylation at chromosome 8q24 in peripheral blood and prostate cancer risk

por Barry, Kathryn Hughes, Moore, Lee E, Sampson, Joshua N, Koutros, Stella, Yan, Liying, Meyer, Ann, Reddy, Mahitha, Oler, Andrew J, Cook, Michael B, Fraumeni Jr, Joseph F, Yeager, Meredith, Amundadottir, Laufey T, Berndt, Sonja I
Publicado 2017

Cell-type–specific eQTL of primary melanocytes facilitates identification of melanoma susceptibility genes

por Zhang, Tongwu, Choi, Jiyeon, Kovacs, Michael A., Shi, Jianxin, Xu, Mai, Goldstein, Alisa M., Trower, Adam J., Bishop, D. Timothy, Iles, Mark M., Duffy, David L., MacGregor, Stuart, Amundadottir, Laufey T., Law, Matthew H., Loftus, Stacie K., Pavan, William J., Brown, Kevin M.
Publicado 2018

The BARD1 Cys557Ser Variant and Breast Cancer Risk in Iceland

por Stacey, Simon N, Sulem, Patrick, Johannsson, Oskar T, Helgason, Agnar, Gudmundsson, Julius, Kostic, Jelena P, Kristjansson, Kristleifur, Jonsdottir, Thora, Sigurdsson, Helgi, Hrafnkelsson, Jon, Johannsson, Jakob, Sveinsson, Thorarinn, Myrdal, Gardar, Grimsson, Hlynur Niels, Bergthorsson, Jon T, Amundadottir, Laufey T, Gulcher, Jeffrey R, Thorsteinsdottir, Unnur, Kong, Augustine, Stefansson, Kari
Publicado 2006

Comprehensive resequence analysis of a 136 kb region of human chromosome 8q24 associated with prostate and colon cancers

por Yeager, Meredith, Xiao, Nianqing, Hayes, Richard B., Bouffard, Pascal, Desany, Brian, Burdett, Laura, Orr, Nick, Matthews, Casey, Qi, Liqun, Crenshaw, Andrew, Markovic, Zdenek, Fredrikson, Karin M., Jacobs, Kevin B., Amundadottir, Laufey, Jarvie, Thomas P., Hunter, David J., Hoover, Robert, Thomas, Gilles, Harkins, Timothy T., Chanock, Stephen J.
Publicado 2008

Transcriptional regulation by NR5A2 links differentiation and inflammation in the pancreas

por Cobo, Isidoro, Martinelli, Paola, Flández, Marta, Bakiri, Latifa, Zhang, Mingfeng, Carrillo-de-Santa-Pau, Enrique, Jia, Jinping, Sánchez-Arévalo Lobo, Víctor J., Megías, Diego, Felipe, Irene, del Pozo, Natalia, Millán, Irene, Thommesen, Liv, Bruland, Torunn, Olson, Sara, Smith, Jill, Schoonjans, Kristina, Bamlet, William R., Petersen, Gloria M, Malats, Núria, Amundadottir, Laufey T, Wagner, Erwin F., Real, Francisco X
Publicado 2018

A comprehensive resequence analysis of the KLK15–KLK3–KLK2 locus on chromosome 19q13.33

por Parikh, Hemang, Deng, Zuoming, Yeager, Meredith, Boland, Joseph, Matthews, Casey, Jia, Jinping, Collins, Irene, White, Ariel, Burdett, Laura, Hutchinson, Amy, Qi, Liqun, Bacior, Jennifer A., Lonsberry, Victor, Rodesch, Matthew J., Jeddeloh, Jeffrey A., Albert, Thomas J., Halvensleben, Heather A., Harkins, Timothy T., Ahn, Jiyoung, Berndt, Sonja I., Chatterjee, Nilanjan, Hoover, Robert, Thomas, Gilles, Hunter, David J., Hayes, Richard B., Chanock, Stephen J., Amundadottir, Laufey
Publicado 2009

3D genomic features across >50 diverse cell types reveal insights into the genomic architecture of childhood obesity

por Trang, Khanh B., Pahl, Matthew C., Pippin, James A., Su, Chun, Littleton, Sheridan H., Sharma, Prabhat, Kulkarni, Nikhil N., Ghanem, Louis R., Terry, Natalie A., O’Brien, Joan M., Wagley, Yadav, Hankenson, Kurt D., Jermusyk, Ashley, Hoskins, Jason W., Amundadottir, Laufey T., Xu, Mai, Brown, Kevin M, Anderson, Stewart A., Yang, Wenli, Titchenell, Paul M., Seale, Patrick, Cook, Laura, Levings, Megan K., Zemel, Babette S., Chesi, Alessandra, Wells, Andrew D., Grant, Struan F.A.
Publicado 2023

Fine mapping the KLK3 locus on chromosome 19q13.33 associated with prostate cancer susceptibility and PSA levels

por Parikh, Hemang, Wang, Zhaoming, Pettigrew, Kerry A., Jia, Jinping, Daugherty, Sarah, Yeager, Meredith, Jacobs, Kevin B., Hutchinson, Amy, Burdett, Laura, Cullen, Michael, Qi, Liqun, Boland, Joseph, Collins, Irene, Albert, Thomas J., Vatten, Lars J., Hveem, Kristian, Njølstad, Inger, Cancel-Tassin, Geraldine, Cussenot, Olivier, Valeri, Antoine, Virtamo, Jarmo, Thun, Michael J., Feigelson, Heather Spencer, Diver, W. Ryan, Chatterjee, Nilanjan, Thomas, Gilles, Albanes, Demetrius, Chanock, Stephen J., Hunter, David J., Hoover, Robert, Hayes, Richard B., Berndt, Sonja I., Sampson, Joshua, Amundadottir, Laufey
Publicado 2011

Characterizing the genetic basis of methylome diversity in histologically normal human lung tissue

por Shi, Jianxin, Marconett, Crystal N., Duan, Jubao, Hyland, Paula L., Li, Peng, Wang, Zhaoming, Wheeler, William, Zhou, Beiyun, Campan, Mihaela, Lee, Diane S., Huang, Jing, Zhou, Weiyin, Triche, Tim, Amundadottir, Laufey, Warner, Andrew, Hutchinson, Amy, Chen, Po-Han, Chung, Brian S.I., Pesatori, Angela C., Consonni, Dario, Bertazzi, Pier Alberto, Bergen, Andrew W., Freedman, Mathew, Siegmund, Kimberly D., Berman, Benjamin P., Borok, Zea, Chatterjee, Nilanjan, Tucker, Margaret A., Caporaso, Neil E., Chanock, Stephen J., Laird-Offringa, Ite A., Landi, Maria Teresa
Publicado 2014

Y chromosome haplogroups and prostate cancer in populations of European and Ashkenazi Jewish ancestry

por Wang, Zhaoming, Parikh, Hemang, Jia, Jinping, Myers, Timothy, Yeager, Meredith, Jacobs, Kevin B., Hutchinson, Amy, Burdett, Laurie, Ghosh, Arpita, Thun, Michael J., Gapstur, Susan M., Ryan Diver, W., Virtamo, Jarmo, Albanes, Demetrius, Cancel-Tassin, Geraldine, Valeri, Antoine, Cussenot, Olivier, Offit, Kenneth, Giovannucci, Ed, Ma, Jing, Stampfer, Meir J., Michael Gaziano, J., Hunter, David J., Dutra-Clarke, Ana, Kirchhoff, Tomas, Alavanja, Michael, Freeman, Laura B., Koutros, Stella, Hoover, Robert, Berndt, Sonja I., Hayes, Richard B., Agalliu, Ilir, Burk, Robert D., Wacholder, Sholom, Thomas, Gilles, Amundadottir, Laufey
Publicado 2012

Evaluation of Association of HNF1B Variants with Diverse Cancers: Collaborative Analysis of Data from 19 Genome-Wide Association Studies

por Elliott, Katherine S., Zeggini, Eleftheria, McCarthy, Mark I., Gudmundsson, Julius, Sulem, Patrick, Stacey, Simon N., Thorlacius, Steinunn, Amundadottir, Laufey, Grönberg, Henrik, Xu, Jianfeng, Gaborieau, Valerie, Eeles, Rosalind A., Neal, David E., Donovan, Jenny L., Hamdy, Freddie C., Muir, Kenneth, Hwang, Shih-Jen, Spitz, Margaret R., Zanke, Brent, Carvajal-Carmona, Luis, Brown, Kevin M., Hayward, Nicholas K., Macgregor, Stuart, Tomlinson, Ian P. M., Lemire, Mathieu, Amos, Christopher I., Murabito, Joanne M., Isaacs, William B., Easton, Douglas F., Brennan, Paul, Barkardottir, Rosa B., Gudbjartsson, Daniel F., Rafnar, Thorunn, Hunter, David J., Chanock, Stephen J., Stefansson, Kari, Ioannidis, John P. A.
Publicado 2010

Winner's Curse Correction and Variable Thresholding Improve Performance of Polygenic Risk Modeling Based on Genome-Wide Association Study Summary-Level Data

por Shi, Jianxin, Park, Ju-Hyun, Duan, Jubao, Berndt, Sonja T., Moy, Winton, Yu, Kai, Song, Lei, Wheeler, William, Hua, Xing, Silverman, Debra, Garcia-Closas, Montserrat, Hsiung, Chao Agnes, Figueroa, Jonine D., Cortessis, Victoria K., Malats, Núria, Karagas, Margaret R., Vineis, Paolo, Chang, I-Shou, Lin, Dongxin, Zhou, Baosen, Seow, Adeline, Matsuo, Keitaro, Hong, Yun-Chul, Caporaso, Neil E., Wolpin, Brian, Jacobs, Eric, Petersen, Gloria M., Klein, Alison P., Li, Donghui, Risch, Harvey, Sanders, Alan R., Hsu, Li, Schoen, Robert E., Brenner, Hermann, Stolzenberg-Solomon, Rachael, Gejman, Pablo, Lan, Qing, Rothman, Nathaniel, Amundadottir, Laufey T., Landi, Maria Teresa, Levinson, Douglas F., Chanock, Stephen J., Chatterjee, Nilanjan
Publicado 2016