Disrupting enzyme fluidity

por Anand, Ganesh Srinivasan
Publicado 2021

Conformational changes in SARS-CoV-2 spike from the delta variant enhances viral transmissibility

por Venkatakrishnan, Varun, Braet, Sean, Buckley, Theresa, Anand, Ganesh S.
Publicado 2022

Impaired cAMP processivity by phosphodiesterase-protein kinase A complexes in acrodysostosis

por Venkatakrishnan, Varun, Ghode, Abhijeet, Tulsian, Nikhil K., Anand, Ganesh S.
Publicado 2023

Molecular interaction between natural IgG and ficolin – mechanistic insights on adaptive-innate immune crosstalk

por Panda, Saswati, Zhang, Jing, Yang, Lifeng, Anand, Ganesh S., Ding, Jeak L.
Publicado 2014

A pH-dependent cluster of charges in a conserved cryptic pocket on flaviviral envelopes

por Zuzic, Lorena, Marzinek, Jan K, Anand, Ganesh S, Warwicker, Jim, Bond, Peter J
Publicado 2023

A Disordered Region in the EvpP Protein from the Type VI Secretion System of Edwardsiella tarda is Essential for EvpC Binding

por Hu, Wentao, Anand, Ganesh, Sivaraman, J., Leung, Ka Yin, Mok, Yu-Keung
Publicado 2014

Cyclic nucleotide binding and structural changes in the isolated GAF domain of Anabaena adenylyl cyclase, CyaB2

por Biswas, Kabir Hassan, Badireddy, Suguna, Rajendran, Abinaya, Anand, Ganesh Srinivasan, Visweswariah, Sandhya S.
Publicado 2015

Predicting Allosteric Effects from Orthosteric Binding in Hsp90-Ligand Interactions: Implications for Fragment-Based Drug Design

por Chandramohan, Arun, Krishnamurthy, Srinath, Larsson, Andreas, Nordlund, Paer, Jansson, Anna, Anand, Ganesh S.
Publicado 2016

Development of Phosphodiesterase–Protein-Kinase Complexes as Novel Targets for Discovery of Inhibitors with Enhanced Specificity

por Tulsian, Nikhil K., Sin, Valerie Jia-En, Koh, Hwee-Ling, Anand, Ganesh S.
Publicado 2021

Dengue virus strain 2 capsid protein switches the annealing pathway and reduces intrinsic dynamics of the conserved 5’ untranslated region

por Yong, Xin Ee, Raghuvamsi, Palur Venkata, Anand, Ganesh S., Wohland, Thorsten, Sharma, Kamal K.
Publicado 2021

Dengue virus 2 capsid protein chaperones the strand displacement of 5′-3′ cyclization sequences

por Yong, Xin Ee, Palur, V Raghuvamsi, Anand, Ganesh S, Wohland, Thorsten, Sharma, Kamal K
Publicado 2021

Timeline of changes in spike conformational dynamics in emergent SARS-CoV-2 variants reveal progressive stabilization of trimer stalk and enhanced NTD dynamics

por Anand, Ganesh S., Braet, Sean, Buckley, Theresa, Venkatakrishnan, Varun, Dam, Kim-Marie, Bjorkman, Pamela J.
Publicado 2023

Ligand-mediated changes in conformational dynamics of NpmA: implications for ribosomal interactions

por Husain, Nilofer, Tulsian, Nikhil Kumar, Chien, Wang Loo, Suresh, Sushant, Anand, Ganesh Srinivasan, Sivaraman, J.
Publicado 2016

Evolution of allostery in the cyclic nucleotide binding module

por Kannan, Natarajan, Wu, Jian, Anand, Ganesh S, Yooseph, Shibu, Neuwald, Andrew F, Venter, J Craig, Taylor, Susan S
Publicado 2007

Timeline of changes in spike conformational dynamics in emergent SARS-CoV-2 variants reveal progressive stabilization of trimer stalk with altered NTD dynamics

por Braet, Sean M, Buckley, Theresa SC, Venkatakrishnan, Varun, Dam, Kim-Marie A, Bjorkman, Pamela J, Anand, Ganesh S
Publicado 2023

Ligand-induced shifts in conformational ensembles that describe transcriptional activation

por Khan, Sabab Hasan, Braet, Sean M, Koehler, Stephen John, Elacqua, Elizabeth, Anand, Ganesh Srinivasan, Okafor, C Denise
Publicado 2022

The ganglioside GM1a functions as a coreceptor/attachment factor for dengue virus during infection

por Tantirimudalige, Sarala Neomi, Raghuvamsi, Palur Venkata, Sharma, Kamal Kant, Wei Bao, Jonathan Chua, Anand, Ganesh S., Wohland, Thorsten
Publicado 2022

Structural Basis of Oligomerization of N-Terminal Domain of Spider Aciniform Silk Protein

por Chakraborty, Rusha, Fan, Jing-song, Lai, Chong Cheong, Raghuvamsi, Palur Venkata, Chee, Pin Xuan, Anand, Ganesh Srinivasan, Yang, Daiwen
Publicado 2020

Synergistic Allostery in Multiligand-Protein Interactions

por Ghode, Abhijeet, Gross, Lissy Z.F., Tee, Wei-Ven, Guarnera, Enrico, Berezovsky, Igor N., Biondi, Ricardo M., Anand, Ganesh S.
Publicado 2020

SARS-CoV-2 spike protein as a bacterial lipopolysaccharide delivery system in an overzealous inflammatory cascade

por Samsudin, Firdaus, Raghuvamsi, Palur, Petruk, Ganna, Puthia, Manoj, Petrlova, Jitka, MacAry, Paul, Anand, Ganesh S, Bond, Peter J, Schmidtchen, Artur
Publicado 2022