Insights from the protein interaction Universe of the multifunctional “Goldilocks” kinase DYRK1A

por Ananthapadmanabhan, Varsha, Shows, Kathryn H., Dickinson, Amanda J., Litovchick, Larisa
Publicado 2023

The cell cycle regulatory DREAM complex is disrupted by high expression of oncogenic B-Myb

por Iness, Audra N., Felthousen, Jessica, Ananthapadmanabhan, Varsha, Sesay, Fatmata, Saini, Siddharth, Guiley, Keelan Z., Rubin, Seth M., Dozmorov, Mikhail, Litovchick, Larisa
Publicado 2018

DYRK1A regulates the recruitment of 53BP1 to the sites of DNA damage in part through interaction with RNF169

por R. Menon, Vijay, Ananthapadmanabhan, Varsha, Swanson, Selene, Saini, Siddharth, Sesay, Fatmata, Yakovlev, Vasily, Florens, Laurence, DeCaprio, James A., P. Washburn, Michael, Dozmorov, Mikhail, Litovchick, Larisa
Publicado 2019

Milademetan is a highly potent MDM2 inhibitor in Merkel cell carcinoma

por Ananthapadmanabhan, Varsha, Frost, Thomas C., Soroko, Kara M., Knott, Aine, Magliozzi, Brianna J., Gokhale, Prafulla C., Tirunagaru, Vijaya G., Doebele, Robert C., DeCaprio, James A.
Publicado 2022

Reversal of viral and epigenetic HLA class I repression in Merkel cell carcinoma

por Lee, Patrick C., Klaeger, Susan, Le, Phuong M., Korthauer, Keegan, Cheng, Jingwei, Ananthapadmanabhan, Varsha, Frost, Thomas C., Stevens, Jonathan D., Wong, Alan Y.L., Iorgulescu, J. Bryan, Tarren, Anna Y., Chea, Vipheaviny A., Carulli, Isabel P., Lemvigh, Camilla K., Pedersen, Christina B., Gartin, Ashley K., Sarkizova, Siranush, Wright, Kyle T., Li, Letitia W., Nomburg, Jason, Li, Shuqiang, Huang, Teddy, Liu, Xiaoxi, Pomerance, Lucas, Doherty, Laura M., Apffel, Annie M., Wallace, Luke J., Rachimi, Suzanna, Felt, Kristen D., Wolff, Jacquelyn O., Witten, Elizabeth, Zhang, Wandi, Neuberg, Donna, Lane, William J., Zhang, Guanglan, Olsen, Lars R., Thakuria, Manisha, Rodig, Scott J., Clauser, Karl R., Starrett, Gabriel J., Doench, John G., Buhrlage, Sara J., Carr, Steven A., DeCaprio, James A., Wu, Catherine J., Keskin, Derin B.
Publicado 2022