Proteolytic activation of proapoptotic kinase protein kinase Cδ by tumor necrosis factor α death receptor signaling in dopaminergic neurons during neuroinflammation

por Gordon, Richard, Anantharam, Vellareddy, Kanthasamy, Anumantha G, Kanthasamy, Arthi
Publicado 2012

Environmental neurotoxin dieldrin induces apoptosis via caspase-3-dependent proteolytic activation of protein kinase C delta (PKCdelta): Implications for neurodegeneration in Parki...

por Kanthasamy, Anumantha G, Kitazawa, Masashi, Yang, Yongjie, Anantharam, Vellareddy, Kanthasamy, Arthi
Publicado 2008

Protein kinase D1 (PKD1) activation mediates a compensatory protective response during early stages of oxidative stress-induced neuronal degeneration

por Asaithambi, Arunkumar, Kanthasamy, Arthi, Saminathan, Hariharan, Anantharam, Vellareddy, Kanthasamy, Anumantha G
Publicado 2011

N-Acetyl Cysteine Protects against Methamphetamine-Induced Dopaminergic Neurodegeneration via Modulation of Redox Status and Autophagy in Dopaminergic Cells

por Chandramani Shivalingappa, Prashanth, Jin, Huajun, Anantharam, Vellareddy, Kanthasamy, Anumantha, Kanthasamy, Arthi
Publicado 2012

Proteasome inhibitor-induced apoptosis is mediated by positive feedback amplification of PKCδ proteolytic activation and mitochondrial translocation

por Sun, Faneng, Kanthasamy, Arthi, Song, Chunjuan, Yang, Yongjie, Anantharam, Vellareddy, Kanthasamy, Anumantha G
Publicado 2008

Microglial immune regulation by epigenetic reprogramming through histone H3K27 acetylation in neuroinflammation

por Huang, Minhong, Malovic, Emir, Ealy, Alyssa, Jin, Huajun, Anantharam, Vellareddy, Kanthasamy, Arthi, Kanthasamy, Anumantha G.
Publicado 2023

Neuroprotective Effect of Resveratrol Against Methamphetamine-Induced Dopaminergic Apoptotic Cell Death in a Cell Culture Model of Neurotoxicity

por Kanthasamy, Kavin, Gordon, Richard, Jin, Huajun, Anantharam, Vellareddy, Ali, Syed, Kanthasamy, Anumantha G, Kanthasamy, Arthi
Publicado 2011

Protein Kinase D1 (PKD1) Phosphorylation Promotes Dopaminergic Neuronal Survival during 6-OHDA-Induced Oxidative Stress

por Asaithambi, Arunkumar, Ay, Muhammet, Jin, Huajun, Gosh, Anamitra, Anantharam, Vellareddy, Kanthasamy, Arthi, Kanthasamy, Anumantha G.
Publicado 2014

Manganese-Induced Neurotoxicity: New Insights Into the Triad of Protein Misfolding, Mitochondrial Impairment, and Neuroinflammation

por Harischandra, Dilshan S., Ghaisas, Shivani, Zenitsky, Gary, Jin, Huajun, Kanthasamy, Arthi, Anantharam, Vellareddy, Kanthasamy, Anumantha G.
Publicado 2019

Integrated Organotypic Slice Cultures and RT-QuIC (OSCAR) Assay: Implications for Translational Discovery in Protein Misfolding Diseases

por Kondru, Naveen, Manne, Sireesha, Greenlee, Justin, West Greenlee, Heather, Anantharam, Vellareddy, Halbur, Patrick, Kanthasamy, Arthi, Kanthasamy, Anumantha
Publicado 2017

Fyn Kinase-Mediated PKCδ Y311 Phosphorylation Induces Dopaminergic Degeneration in Cell Culture and Animal Models: Implications for the Identification of a New Pharmacological Targ...

por Saminathan, Hariharan, Ghosh, Anamitra, Zhang, Danhui, Song, Chunjuan, Jin, Huajun, Anantharam, Vellareddy, Kanthasamy, Arthi, Kanthasamy, Anumantha G.
Publicado 2021

Mechanistic Insights Into Gut Microbiome Dysbiosis-Mediated Neuroimmune Dysregulation and Protein Misfolding and Clearance in the Pathogenesis of Chronic Neurodegenerative Disorder...

por Padhi, Piyush, Worth, Carter, Zenitsky, Gary, Jin, Huajun, Sambamurti, Kumar, Anantharam, Vellareddy, Kanthasamy, Arthi, Kanthasamy, Anumantha G.
Publicado 2022

Anti-inflammatory and neuroprotective effects of an orally active apocynin derivative in pre-clinical models of Parkinson’s disease

por Ghosh, Anamitra, Kanthasamy, Arthi, Joseph, Joy, Anantharam, Vellareddy, Srivastava, Pallavi, Dranka, Brian P, Kalyanaraman, Balaraman, Kanthasamy, Anumantha G
Publicado 2012

Impact of Environmental Risk Factors on Mitochondrial Dysfunction, Neuroinflammation, Protein Misfolding, and Oxidative Stress in the Etiopathogenesis of Parkinson’s Disease

por Huang, Minhong, Bargues-Carot, Alejandra, Riaz, Zainab, Wickham, Hannah, Zenitsky, Gary, Jin, Huajun, Anantharam, Vellareddy, Kanthasamy, Arthi, Kanthasamy, Anumantha G.
Publicado 2022

Mitochondrial dysfunction–induced H3K27 hyperacetylation perturbs enhancers in Parkinson’s disease

por Huang, Minhong, Lou, Dan, Charli, Adhithiya, Kong, Dehui, Jin, Huajun, Zenitsky, Gary, Anantharam, Vellareddy, Kanthasamy, Arthi, Wang, Zhibin, Kanthasamy, Anumantha G.
Publicado 2021

Tumor Necrosis Factor-Like Weak Inducer of Apoptosis (TWEAK) Enhances Activation of STAT3/NLRC4 Inflammasome Signaling Axis through PKCδ in Astrocytes: Implications for Parkinson’s...

por Samidurai, Manikandan, Tarale, Prashant, Janarthanam, Chelva, Estrada, Crystal Gomez, Gordon, Richard, Zenitsky, Gary, Jin, Huajun, Anantharam, Vellareddy, Kanthasamy, Anumantha G., Kanthasamy, Arthi
Publicado 2020

An Ex Vivo Brain Slice Culture Model of Chronic Wasting Disease: Implications for Disease Pathogenesis and Therapeutic Development

por Kondru, Naveen, Manne, Sireesha, Kokemuller, Robyn, Greenlee, Justin, Greenlee, M. Heather West, Nichols, Tracy, Kong, Qingzhong, Anantharam, Vellareddy, Kanthasamy, Arthi, Halbur, Patrick, Kanthasamy, Anumantha G.
Publicado 2020

PKC Delta Activation Promotes Endoplasmic Reticulum Stress (ERS) and NLR Family Pyrin Domain-Containing 3 (NLRP3) Inflammasome Activation Subsequent to Asynuclein-Induced Microglia...

por Samidurai, Manikandan, Palanisamy, Bharathi N., Bargues-Carot, Alejandra, Hepker, Monica, Kondru, Naveen, Manne, Sireesha, Zenitsky, Gary, Jin, Huajun, Anantharam, Vellareddy, Kanthasamy, Anumantha G., Kanthasamy, Arthi
Publicado 2021

Mitochondrial impairment in microglia amplifies NLRP3 inflammasome proinflammatory signaling in cell culture and animal models of Parkinson’s disease

por Sarkar, Souvarish, Malovic, Emir, Harishchandra, Dilshan S., Ghaisas, Shivani, Panicker, Nikhil, Charli, Adhithiya, Palanisamy, Bharathi N., Rokad, Dharmin, Jin, Huajun, Anantharam, Vellareddy, Kanthasamy, Arthi, Kanthasamy, Anumantha G.
Publicado 2017

Chronic Manganese Exposure and the Enteric Nervous System: An in Vitro and Mouse in Vivo Study

por Ghaisas, Shivani, Harischandra, Dilshan S., Palanisamy, Bharathi, Proctor, Alexandra, Jin, Huajun, Dutta, Somak, Sarkar, Souvarish, Langley, Monica, Zenitsky, Gary, Anantharam, Vellareddy, Kanthasamy, Arthi, Phillips, Gregory J., Kanthasamy, Anumantha
Publicado 2021