Carfilzomib demonstrates broad anti-tumor activity in pre-clinical non-small cell and small cell lung cancer models

por Baker, Amanda F, Hanke, Neale T, Sands, Barbara J, Carbajal, Liliana, Anderl, Janet L, Garland, Linda L
Publicado 2014

Zetomipzomib (KZR-616) attenuates lupus in mice via modulation of innate and adaptive immune responses

por Muchamuel, Tony, Fan, R. Andrea, Anderl, Janet L., Bomba, Darrin J., Johnson, Henry W. B., Lowe, Eric, Tuch, Brian B., McMinn, Dustin L., Millare, Beatriz, Kirk, Christopher J.
Publicado 2023

Interferon-γ-induced upregulation of immunoproteasome subunit assembly overcomes bortezomib resistance in human hematological cell lines

por Niewerth, Denise, Kaspers, Gertjan JL, Assaraf, Yehuda G, van Meerloo, Johan, Kirk, Christopher J, Anderl, Janet, Blank, Jonathan L, van de Ven, Peter M, Zweegman, Sonja, Jansen, Gerrit, Cloos, Jacqueline
Publicado 2014

Immunoproteasome functions explained by divergence in cleavage specificity and regulation

por Winter, Michael B, La Greca, Florencia, Arastu-Kapur, Shirin, Caiazza, Francesco, Cimermancic, Peter, Buchholz, Tonia J, Anderl, Janet L, Ravalin, Matthew, Bohn, Markus F, Sali, Andrej, O'Donoghue, Anthony J, Craik, Charles S
Publicado 2017

Signal peptide mimicry primes Sec61 for client-selective inhibition

por Rehan, Shahid, Tranter, Dale, Sharp, Phillip P., Craven, Gregory B., Lowe, Eric, Anderl, Janet L., Muchamuel, Tony, Abrishami, Vahid, Kuivanen, Suvi, Wenzell, Nicole A., Jennings, Andy, Kalyanaraman, Chakrapani, Strandin, Tomas, Javanainen, Matti, Vapalahti, Olli, Jacobson, Matthew P., McMinn, Dustin, Kirk, Christopher J., Huiskonen, Juha T., Taunton, Jack, Paavilainen, Ville O.
Publicado 2023

Overcoming bortezomib resistance in human B cells by anti-CD20/rituximab-mediated complement-dependent cytotoxicity and epoxyketone-based irreversible proteasome inhibitors

por Verbrugge, Sue Ellen, Al, Marjon, Assaraf, Yehuda G, Niewerth, Denise, van Meerloo, Johan, Cloos, Jacqueline, van der Veer, Michael, Scheffer, George L, Peters, Godefridus J, Chan, Elena T, Anderl, Janet L, Kirk, Christopher J, Zweegman, Sonja, Dijkmans, Ben AC, Lems, Willem F, Scheper, Rik J, de Gruijl, Tanja D, Jansen, Gerrit
Publicado 2013