Genetic Loss of Sucrase-Isomaltase Function: Mechanisms, Implications, and Future Perspectives

por Senftleber, Ninna Karsbæk, Ramne, Stina, Moltke, Ida, Jørgensen, Marit Eika, Albrechtsen, Anders, Hansen, Torben, Andersen, Mette K
Publicado 2023

Latent Autoimmune Diabetes in Adults Differs Genetically From Classical Type 1 Diabetes Diagnosed After the Age of 35 Years

por Andersen, Mette K., Lundgren, Virve, Turunen, Joni A., Forsblom, Carol, Isomaa, Bo, Groop, Per-Henrik, Groop, Leif, Tuomi, Tiinamaija
Publicado 2010

A shared somatic translocation involving CUX1 in monozygotic twins as an early driver of AMKL in Down syndrome

por Bache, Iben, Wadt, Karin, Mehrjouy, Mana M., Rossing, Maria, Østrup, Olga, Byrjalsen, Anna, Tommerup, Niels, Metzner, Marlen, Vyas, Paresh, Schmiegelow, Kjeld, Lausen, Birgitte, Andersen, Mette K.
Publicado 2020

High preharvest donor Foxp3 mRNA level predicts late relapse of acute lymphoblastic leukaemia after haematopoietic stem cell transplantation

por Jacobsen, Niels, Frisch, Tina, Keiding, Niels, Heilmann, Carsten, Sengeløv, Henrik, Madsen, Hans O., Marquart, Hanne, Dickmeiss, Ebbe, Andersen, Mette K., Christiansen, Claus B., Ryder, Lars P.
Publicado 2021

Structural aberrations are associated with poor survival in patients with clonal cytopenia of undetermined significance

por Mikkelsen, Stine U., Safavi, Setareh, Dimopoulos, Konstantinos, O’Rourke, Colm J., Andersen, Mette K., Holm, Mette S., Marcher, Claus W., Andersen, Jesper B., Hansen, Jakob W., Grønbæk, Kirsten
Publicado 2020

The genetic history of Greenlandic-European contact

por Waples, Ryan K., Hauptmann, Aviaja L., Seiding, Inge, Jørsboe, Emil, Jørgensen, Marit E., Grarup, Niels, Andersen, Mette K., Larsen, Christina V.L., Bjerregaard, Peter, Hellenthal, Garrett, Hansen, Torben, Albrechtsen, Anders, Moltke, Ida
Publicado 2021

Birthweight is associated with clinical characteristics in people with recently diagnosed type 2 diabetes

por Hansen, Aleksander L., Thomsen, Reimar W., Brøns, Charlotte, Svane, Helene M. L., Jensen, Rasmus T., Andersen, Mette K., Hansen, Torben, Nielsen, Jens S., Vestergaard, Peter, Højlund, Kurt, Jessen, Niels, Olsen, Michael H., Sørensen, Henrik T., Vaag, Allan A.
Publicado 2023

Identification of novel high-impact recessively inherited type 2 diabetes risk variants in the Greenlandic population

por Grarup, Niels, Moltke, Ida, Andersen, Mette K., Bjerregaard, Peter, Larsen, Christina V. L., Dahl-Petersen, Inger K., Jørsboe, Emil, Tiwari, Hemant K., Hopkins, Scarlett E., Wiener, Howard W., Boyer, Bert B., Linneberg, Allan, Pedersen, Oluf, Jørgensen, Marit E., Albrechtsen, Anders, Hansen, Torben
Publicado 2018

Nordic Guidelines for Germline Predisposition to Myeloid Neoplasms in Adults: Recommendations for Genetic Diagnosis, Clinical Management and Follow-up

por Baliakas, Panagiotis, Tesi, Bianca, Wartiovaara-Kautto, Ulla, Stray-Pedersen, Asbjørg, Friis, Lone Smidstrup, Dybedal, Ingunn, Hovland, Randi, Jahnukainen, Kirsi, Raaschou-Jensen, Klas, Ljungman, Per, Rustad, Cecilie F., Lautrup, Charlotte K., Kilpivaara, Outi, Kittang, Astrid Olsnes, Grønbæk, Kirsten, Cammenga, Jörg, Hellström-Lindberg, Eva, Andersen, Mette K.
Publicado 2019

Loss-of-function variants in ADCY3 increase risk of obesity and type 2 diabetes

por Grarup, Niels, Moltke, Ida, Andersen, Mette K., Dalby, Maria, Vitting-Seerup, Kristoffer, Kern, Timo, Mahendran, Yuvaraj, Jørsboe, Emil, Larsen, Christina V. L., Dahl-Petersen, Inger K., Gilly, Arthur, Suveges, Daniel, Dedoussis, George, Zeggini, Eleftheria, Pedersen, Oluf, Andersson, Robin, Bjerregaard, Peter, Jørgensen, Marit E., Albrechtsen, Anders, Hansen, Torben
Publicado 2018

High Plasma Levels of Soluble Lectin‐like Oxidized Low‐Density Lipoprotein Receptor‐1 Are Associated With Inflammation and Cardiometabolic Risk Profiles in Pediatric Overweight and...

por Stinson, Sara E., Jonsson, Anna E., Andersen, Mette K., Lund, Morten A. V., Holm, Louise Aas, Fonvig, Cilius E., Huang, Yun, Stankevič, Evelina, Juel, Helene Bæk, Ängquist, Lars, Sørensen, Thorkild I. A., Ongstad, Emily L., Gaddipati, Ranjitha, Grimsby, Joseph, Rhodes, Christopher J., Pedersen, Oluf, Christiansen, Michael, Holm, Jens‐Christian, Hansen, Torben
Publicado 2023

Genetic Subtypes and Outcome of Patients Aged 1 to 45 Years Old With Acute Lymphoblastic Leukemia in the NOPHO ALL2008 Trial

por Norén-Nyström, Ulrika, Andersen, Mette K., Barbany, Gisela, Dirse, Vaidas, Eilert-Olsen, Martine, Engvall, Marie, Harila-Saari, Arja, Heyman, Mats, Hovland, Randi, Häikiö, Satu, Jónsson, Jón J., Karhu, Ritva, Kjeldsen, Eigil, Norberg, Anna, Preiss, Birgitte S., Pulkkinen, Kati, Quist-Paulsen, Petter, Räsänen, Hannele, Schmiegelow, Kjeld, Seitsonen, Anne, Sjögren, Helene, Tammur, Pille, Johansson, Bertil
Publicado 2023

An LDLR missense variant poses high risk of familial hypercholesterolemia in 30% of Greenlanders and offers potential of early cardiovascular disease intervention

por Jørsboe, Emil, Andersen, Mette K., Skotte, Line, Stæger, Frederik F., Færgeman, Nils J., Hanghøj, Kristian, Santander, Cindy G., Senftleber, Ninna K., Diaz, Lars J., Overvad, Maria, Waples, Ryan K., Geller, Frank, Bjerregaard, Peter, Melbye, Mads, Larsen, Christina V.L., Feenstra, Bjarke, Anders Koch, Jørgensen, Marit E., Grarup, Niels, Moltke, Ida, Albrechtsen, Anders, Hansen, Torben
Publicado 2022

The derived allele of a novel intergenic variant at chromosome 11 associates with lower body mass index and a favorable metabolic phenotype in Greenlanders

por Andersen, Mette K., Jørsboe, Emil, Skotte, Line, Hanghøj, Kristian, Sandholt, Camilla H., Moltke, Ida, Grarup, Niels, Kern, Timo, Mahendran, Yuvaraj, Søborg, Bolette, Bjerregaard, Peter, Larsen, Christina V. L., Dahl-Petersen, Inger K., Tiwari, Hemant K., Feenstra, Bjarke, Koch, Anders, Wiener, Howard W., Hopkins, Scarlett E., Pedersen, Oluf, Melbye, Mads, Boyer, Bert B., Jørgensen, Marit E., Albrechtsen, Anders, Hansen, Torben
Publicado 2020

A novel splice-affecting HNF1A variant with large population impact on diabetes in Greenland

por Thuesen, Anne Cathrine Baun, Stæger, Frederik Filip, Kaci, Alba, Solheim, Marie Holm, Aukrust, Ingvild, Jørsboe, Emil, Santander, Cindy G., Andersen, Mette K., Li, Zilong, Gilly, Arthur, Stinson, Sara Elizabeth, Gjesing, Anette Prior, Bjerregaard, Peter, Pedersen, Michael Lynge, Larsen, Christina Viskum Lytken, Grarup, Niels, Jørgensen, Marit E., Zeggini, Eleftheria, Bjørkhaug, Lise, Njølstad, Pål Rasmus, Albrechtsen, Anders, Moltke, Ida, Hansen, Torben
Publicado 2022

Precision subclassification of type 2 diabetes: a systematic review

por Misra, Shivani, Wagner, Robert, Ozkan, Bige, Schön, Martin, Sevilla-Gonzalez, Magdalena, Prystupa, Katsiaryna, Wang, Caroline C., Kreienkamp, Raymond J., Cromer, Sara J., Rooney, Mary R., Duan, Daisy, Thuesen, Anne Cathrine Baun, Wallace, Amelia S., Leong, Aaron, Deutsch, Aaron J., Andersen, Mette K., Billings, Liana K., Eckel, Robert H., Sheu, Wayne Huey-Herng, Hansen, Torben, Stefan, Norbert, Goodarzi, Mark O., Ray, Debashree, Selvin, Elizabeth, Florez, Jose C., Meigs, James B., Udler, Miriam S.
Publicado 2023

Life-threatening viral disease in a novel form of autosomal recessive IFNAR2 deficiency in the Arctic

por Duncan, Christopher J.A., Skouboe, Morten K., Howarth, Sophie, Hollensen, Anne K., Chen, Rui, Børresen, Malene L., Thompson, Benjamin J., Stremenova Spegarova, Jarmila, Hatton, Catherine F., Stæger, Frederik F., Andersen, Mette K., Whittaker, John, Paludan, Søren R., Jørgensen, Sofie E., Thomsen, Martin K., Mikkelsen, Jacob G., Heilmann, Carsten, Buhas, Daniela, Øbro, Nina F., Bay, Jakob T., Marquart, Hanne V., de la Morena, M. Teresa, Klejka, Joseph A., Hirschfeld, Matthew, Borgwardt, Line, Forss, Isabel, Masmas, Tania, Poulsen, Anja, Noya, Francisco, Rouleau, Guy, Hansen, Torben, Zhou, Sirui, Albrechtsen, Anders, Alizadehfar, Reza, Allenspach, Eric J., Hambleton, Sophie, Mogensen, Trine H.
Publicado 2022

First Genome-Wide Association Study of Latent Autoimmune Diabetes in Adults Reveals Novel Insights Linking Immune and Metabolic Diabetes

por Cousminer, Diana L., Ahlqvist, Emma, Mishra, Rajashree, Andersen, Mette K., Chesi, Alessandra, Hawa, Mohammad I., Davis, Asa, Hodge, Kenyaita M., Bradfield, Jonathan P., Zhou, Kaixin, Guy, Vanessa C., Åkerlund, Mikael, Wod, Mette, Fritsche, Lars G., Vestergaard, Henrik, Snyder, James, Højlund, Kurt, Linneberg, Allan, Käräjämäki, Annemari, Brandslund, Ivan, Kim, Cecilia E., Witte, Daniel, Sørgjerd, Elin Pettersen, Brillon, David J., Pedersen, Oluf, Beck-Nielsen, Henning, Grarup, Niels, Pratley, Richard E., Rickels, Michael R., Vella, Adrian, Ovalle, Fernando, Melander, Olle, Harris, Ronald I., Varvel, Stephen, Grill, Valdemar E.R., Hakonarson, Hakon, Froguel, Philippe, Lonsdale, John T., Mauricio, Didac, Schloot, Nanette C., Khunti, Kamlesh, Greenbaum, Carla J., Åsvold, Bjørn Olav, Yderstræde, Knud B., Pearson, Ewan R., Schwartz, Stanley, Voight, Benjamin F., Hansen, Torben, Tuomi, Tiinamaija, Boehm, Bernhard O., Groop, Leif, Leslie, R. David, Grant, Struan F.A.
Publicado 2018

Genome-wide association study identifies susceptibility loci for acute myeloid leukemia

por Lin, Wei-Yu, Fordham, Sarah E., Hungate, Eric, Sunter, Nicola J., Elstob, Claire, Xu, Yaobo, Park, Catherine, Quante, Anne, Strauch, Konstantin, Gieger, Christian, Skol, Andrew, Rahman, Thahira, Sucheston-Campbell, Lara, Wang, Junke, Hahn, Theresa, Clay-Gilmour, Alyssa I., Jones, Gail L., Marr, Helen J., Jackson, Graham H., Menne, Tobias, Collin, Mathew, Ivey, Adam, Hills, Robert K., Burnett, Alan K., Russell, Nigel H., Fitzgibbon, Jude, Larson, Richard A., Le Beau, Michelle M., Stock, Wendy, Heidenreich, Olaf, Alharbi, Abrar, Allsup, David J., Houlston, Richard S., Norden, Jean, Dickinson, Anne M., Douglas, Elisabeth, Lendrem, Clare, Daly, Ann K., Palm, Louise, Piechocki, Kim, Jeffries, Sally, Bornhäuser, Martin, Röllig, Christoph, Altmann, Heidi, Ruhnke, Leo, Kunadt, Desiree, Wagenführ, Lisa, Cordell, Heather J., Darlay, Rebecca, Andersen, Mette K., Fontana, Maria C., Martinelli, Giovanni, Marconi, Giovanni, Sanz, Miguel A., Cervera, José, Gómez-Seguí, Inés, Cluzeau, Thomas, Moreilhon, Chimène, Raynaud, Sophie, Sill, Heinz, Voso, Maria Teresa, Lo-Coco, Francesco, Dombret, Hervé, Cheok, Meyling, Preudhomme, Claude, Gale, Rosemary E., Linch, David, Gaal-Wesinger, Julia, Masszi, Andras, Nowak, Daniel, Hofmann, Wolf-Karsten, Gilkes, Amanda, Porkka, Kimmo, Milosevic Feenstra, Jelena D., Kralovics, Robert, Grimwade, David, Meggendorfer, Manja, Haferlach, Torsten, Krizsán, Szilvia, Bödör, Csaba, Stölzel, Friedrich, Onel, Kenan, Allan, James M.
Publicado 2021

Author Correction: Genome-wide association study identifies susceptibility loci for acute myeloid leukemia

por Lin, Wei-Yu, Fordham, Sarah E., Hungate, Eric, Sunter, Nicola J., Elstob, Claire, Xu, Yaobo, Park, Catherine, Quante, Anne, Strauch, Konstantin, Gieger, Christian, Skol, Andrew, Rahman, Thahira, Sucheston-Campbell, Lara, Wang, Junke, Hahn, Theresa, Clay-Gilmour, Alyssa I., Jones, Gail L., Marr, Helen J., Jackson, Graham H., Menne, Tobias, Collin, Mathew, Ivey, Adam, Hills, Robert K., Burnett, Alan K., Russell, Nigel H., Fitzgibbon, Jude, Larson, Richard A., Le Beau, Michelle M., Stock, Wendy, Heidenreich, Olaf, Alharbi, Abrar, Allsup, David J., Houlston, Richard S., Norden, Jean, Dickinson, Anne M., Douglas, Elisabeth, Lendrem, Clare, Daly, Ann K., Palm, Louise, Piechocki, Kim, Jeffries, Sally, Bornhäuser, Martin, Röllig, Christoph, Altmann, Heidi, Ruhnke, Leo, Kunadt, Desiree, Wagenführ, Lisa, Cordell, Heather J., Darlay, Rebecca, Andersen, Mette K., Fontana, Maria C., Martinelli, Giovanni, Marconi, Giovanni, Sanz, Miguel A., Cervera, José, Gómez-Seguí, Inés, Cluzeau, Thomas, Moreilhon, Chimène, Raynaud, Sophie, Sill, Heinz, Voso, Maria Teresa, Lo-Coco, Francesco, Dombret, Hervé, Cheok, Meyling, Preudhomme, Claude, Gale, Rosemary E., Linch, David, Gaal-Wesinger, Julia, Masszi, Andras, Nowak, Daniel, Hofmann, Wolf-Karsten, Gilkes, Amanda, Porkka, Kimmo, Milosevic Feenstra, Jelena D., Kralovics, Robert, Grimwade, David, Meggendorfer, Manja, Haferlach, Torsten, Krizsán, Szilvia, Bödör, Csaba, Stölzel, Friedrich, Onel, Kenan, Allan, James M.
Publicado 2022