Prediction of methionine oxidation risk in monoclonal antibodies using a machine learning method

por Sankar, Kannan, Hoi, Kam Hon, Yin, Yizhou, Ramachandran, Prasanna, Andersen, Nisana, Hilderbrand, Amy, McDonald, Paul, Spiess, Christoph, Zhang, Qing
Publicado 2018

High-throughput screening of antibody variants for chemical stability: identification of deamidation-resistant mutants

por DiCara, Danielle M., Andersen, Nisana, Chan, Ruby, Ernst, James A., Ayalon, Gai, Lazar, Greg A., Agard, Nicholas J., Hilderbrand, Amy, Hötzel, Isidro
Publicado 2018

Protein engineering to increase the potential of a therapeutic antibody Fab for long-acting delivery to the eye

por Tesar, Devin, Luoma, Jacob, Wyatt, Emily A., Shi, Catherine, Shatz, Whitney, Hass, Philip E., Mathieu, Mary, Yi, Li, Corn, Jacob E., Maass, Katie F., Wang, Kathryn, Dion, Michelle Z., Andersen, Nisana, Loyet, Kelly M., van Lookeren Campagne, Menno, Rajagopal, Karthikan, Dickmann, Leslie, Scheer, Justin M., Kelley, Robert F.
Publicado 2017