Macrophage checkpoint blockade: results from initial clinical trials, binding analyses, and CD47-SIRPα structure–function

por Jalil, AbdelAziz R, Andrechak, Jason C, Discher, Dennis E
Publicado 2020

Titrating CD47 by mismatch CRISPR-interference reveals incomplete repression can eliminate IgG-opsonized tumors but limits induction of antitumor IgG

por Hayes, Brandon H, Zhu, Hui, Andrechak, Jason C, Dooling, Lawrence J, Discher, Dennis E
Publicado 2023

Multi-day rhythms modulate seizure risk in epilepsy

por Baud, Maxime O., Kleen, Jonathan K., Mirro, Emily A., Andrechak, Jason C., King-Stephens, David, Chang, Edward F., Rao, Vikram R.
Publicado 2018

CD47-SIRPα Checkpoint Disruption in Metastases Requires Tumor-Targeting Antibody for Molecular and Engineered Macrophage Therapies

por Andrechak, Jason C., Dooling, Lawrence J., Tobin, Michael P., Zhang, William, Hayes, Brandon H., Lee, Justine Y., Jin, Xiaoling, Irianto, Jerome, Discher, Dennis E.
Publicado 2022

Chromosomal instability can favor macrophage-mediated immune response and induce a broad, vaccination-like anti-tumor IgG response

por Hayes, Brandon H., Wang, Mai, Zhu, Hui, Phan, Steven H., Andrechak, Jason C., Chang, Alexander H., Dooling, Lawrence J., Tobin, Michael P., Marchena, Tristan, Discher, Dennis E.
Publicado 2023