Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease

por Agostini, Maria L., Andres, Erica L., Sims, Amy C., Graham, Rachel L., Sheahan, Timothy P., Lu, Xiaotao, Smith, Everett Clinton, Case, James Brett, Feng, Joy Y., Jordan, Robert, Ray, Adrian S., Cihlar, Tomas, Siegel, Dustin, Mackman, Richard L., Clarke, Michael O., Baric, Ralph S., Denison, Mark R.
Publicado 2018

Small-Molecule Antiviral β-d-N(4)-Hydroxycytidine Inhibits a Proofreading-Intact Coronavirus with a High Genetic Barrier to Resistance

por Agostini, Maria L., Pruijssers, Andrea J., Chappell, James D., Gribble, Jennifer, Lu, Xiaotao, Andres, Erica L., Bluemling, Gregory R., Lockwood, Mark A., Sheahan, Timothy P., Sims, Amy C., Natchus, Michael G., Saindane, Manohar, Kolykhalov, Alexander A., Painter, George R., Baric, Ralph S., Denison, Mark R.
Publicado 2019

Isolation and growth characterization of novel full length and deletion mutant human MERS-CoV strains from clinical specimens collected during 2015

por Tamin, Azaibi, Queen, Krista, Paden, Clinton R., Lu, Xiaoyan, Andres, Erica, Sakthivel, Senthilkumar K., Li, Yan, Tao, Ying, Zhang, Jing, Kamili, Shifaq, Assiri, Abdullah M., Alshareef, Ali, Alaifan, Taghreed A., Altamimi, Asmaa M., Jokhdar, Hani, Watson, John T., Gerber, Susan I., Tong, Suxiang, Thornburg, Natalie J.
Publicado 2019