Aspirin: A Suicide Inhibitor of Carbonic Anhydrase II

por Andring, Jacob, Combs, Jacob, McKenna, Robert
Publicado 2020

Crystallography and Its Impact on Carbonic Anhydrase Research

por Lomelino, Carrie L., Andring, Jacob T., McKenna, Robert
Publicado 2018

Structure and mechanism of copper–carbonic anhydrase II: a nitrite reductase

por Andring, Jacob T., Kim, Chae Un, McKenna, Robert
Publicado 2020

Structure and mechanism of copper–carbonic anhydrase II: a nitrite reductase. Corrigendum

por Andring, Jacob T., Kim, Chae Un, McKenna, Robert
Publicado 2021

Structural insights into the effect of active-site mutation on the catalytic mechanism of carbonic anhydrase

por Kim, Jin Kyun, Lee, Cheol, Lim, Seon Woo, Andring, Jacob T., Adhikari, Aniruddha, McKenna, Robert, Kim, Chae Un
Publicado 2020

Elucidating the role of metal ions in carbonic anhydrase catalysis

por Kim, Jin Kyun, Lee, Cheol, Lim, Seon Woo, Adhikari, Aniruddha, Andring, Jacob T., McKenna, Robert, Ghim, Cheol-Min, Kim, Chae Un
Publicado 2020

An arrestin-1 surface opposite of its interface with photoactivated rhodopsin engages with enolase-1

por Miranda, Connie Jaqueline, Fernandez, Nicole, Kamel, Nader, Turner, Daniel, Benzenhafer, Del, Bolch, Susan N., Andring, Jacob T., McKenna, Robert, Smith, W. Clay
Publicado 2020

Sulfonamide Inhibitors of Human Carbonic Anhydrases Designed through a Three-Tails Approach: Improving Ligand/Isoform Matching and Selectivity of Action

por Bonardi, Alessandro, Nocentini, Alessio, Bua, Silvia, Combs, Jacob, Lomelino, Carrie, Andring, Jacob, Lucarini, Laura, Sgambellone, Silvia, Masini, Emanuela, McKenna, Robert, Gratteri, Paola, Supuran, Claudiu T.
Publicado 2020

The three-tails approach as a new strategy to improve selectivity of action of sulphonamide inhibitors against tumour-associated carbonic anhydrase IX and XII

por Bonardi, Alessandro, Bua, Silvia, Combs, Jacob, Lomelino, Carrie, Andring, Jacob, Osman, Sameh Mohamed, Toti, Alessandra, Di Cesare Mannelli, Lorenzo, Gratteri, Paola, Ghelardini, Carla, McKenna, Robert, Nocentini, Alessio, Supuran, Claudiu T.
Publicado 2022

First-in-class multifunctional TYMS nonclassical antifolate inhibitor with potent in vivo activity that prolongs survival

por Guijarro, Maria V., Kellish, Patrick C., Dib, Peter E., Paciaroni, Nicholas G., Nawab, Akbar, Andring, Jacob, Kulemina, Lidia, Borrero, Nicholas V., Modenutti, Carlos, Feely, Michael, Nasri, Elham, Seifert, Robert P., Luo, Xiaoping, Bennett, Richard L., Shabashvili, Daniil, Licht, Jonathan D., McKenna, Robert, Roitberg, Adrian, Huigens, Robert W., Kaye, Frederic J., Zajac-Kaye, Maria
Publicado 2023