Multi-omics analysis reveals contextual tumor suppressive and oncogenic gene modules within the acute hypoxic response

por Andrysik, Zdenek, Bender, Heather, Galbraith, Matthew D., Espinosa, Joaquin M.
Publicado 2021

PPM1D suppresses p53-dependent transactivation and cell death by inhibiting the Integrated Stress Response

por Andrysik, Zdenek, Sullivan, Kelly D., Kieft, Jeffrey S., Espinosa, Joaquin M.
Publicado 2022

Mechanisms of transcriptional regulation by p53

por Sullivan, Kelly D, Galbraith, Matthew D, Andrysik, Zdenek, Espinosa, Joaquin M
Publicado 2018

A DR4:tBID axis drives the p53 apoptotic response by promoting oligomerization of poised BAX

por Henry, Ryan E, Andrysik, Zdenek, París, Ramiro, Galbraith, Matthew D, Espinosa, Joaquín M
Publicado 2012

Acetylation and deacetylation of Cdc25A constitutes a novel mechanism for modulating Cdc25A functions with implications for cancer

por Lozada, Enerlyn M., Andrysik, Zdenek, Yin, Moying, Redilla, Nicholas, Rice, Kathryn, Stambrook, Peter J.
Publicado 2016

Antimigraine Drug Avitriptan Is a Ligand and Agonist of Human Aryl Hydrocarbon Receptor that Induces CYP1A1 in Hepatic and Intestinal Cells

por Vyhlídalová, Barbora, Krasulová, Kristýna, Pečinková, Petra, Poulíková, Karolína, Vrzal, Radim, Andrysík, Zdeněk, Chandran, Aneesh, Mani, Sridhar, Dvorak, Zdenek
Publicado 2020

The novel mouse Polo-like kinase 5 responds to DNA damage and localizes in the nucleolus

por Andrysik, Zdenek, Bernstein, William Z., Deng, Li, Myer, David L., Li, Ya-Qin, Tischfield, Jay A., Stambrook, Peter J., Bahassi, El Mustapha
Publicado 2010

Identification of a core TP53 transcriptional program with highly distributed tumor suppressive activity

por Andrysik, Zdenek, Galbraith, Matthew D., Guarnieri, Anna L., Zaccara, Sara, Sullivan, Kelly D., Pandey, Ahwan, MacBeth, Morgan, Inga, Alberto, Espinosa, Joaquín M.
Publicado 2017

Inhibition of Aryl Hydrocarbon Receptor (AhR) Expression Disrupts Cell Proliferation and Alters Energy Metabolism and Fatty Acid Synthesis in Colon Cancer Cells

por Karasová, Martina, Procházková, Jiřina, Tylichová, Zuzana, Fedr, Radek, Ciganek, Miroslav, Machala, Miroslav, Dvořák, Zdeněk, Vyhlídalová, Barbora, Zůvalová, Iveta, Ehrmann, Jiří, Bouchal, Jan, Andrysík, Zdeněk, Vondráček, Jan
Publicado 2022

Global analysis of p53-regulated transcription identifies its direct targets and unexpected regulatory mechanisms

por Allen, Mary Ann, Andrysik, Zdenek, Dengler, Veronica L, Mellert, Hestia S, Guarnieri, Anna, Freeman, Justin A, Sullivan, Kelly D, Galbraith, Matthew D, Luo, Xin, Kraus, W Lee, Dowell, Robin D, Espinosa, Joaquin M
Publicado 2014

FAM193A is a positive regulator of p53 activity

por Szwarc, Maria M., Guarnieri, Anna L., Joshi, Molishree, Duc, Huy N., Laird, Madison C., Pandey, Ahwan, Khanal, Santosh, Dohm, Emily, Bui, Aimee K., Sullivan, Kelly D., Galbraith, Matthew D., Andrysik, Zdenek, Espinosa, Joaquin M.
Publicado 2023

Cell differentiation modifies the p53 transcriptional program through a combination of gene silencing and constitutive transactivation

por Tatavosian, Roubina, Donovan, Micah G., Galbraith, Matthew D., Duc, Huy N., Szwarc, Maria M., Joshi, Molishree U., Frieman, Amy, Bilousova, Ganna, Cao, Yingqiong, Smith, Keith P., Song, Kunhua, Rachubinski, Angela L., Andrysik, Zdenek, Espinosa, Joaquin M.
Publicado 2023

Triplication of the interferon receptor locus contributes to hallmarks of Down syndrome in a mouse model

por Waugh, Katherine A., Minter, Ross, Baxter, Jessica, Chi, Congwu, Galbraith, Matthew D., Tuttle, Kathryn D., Eduthan, Neetha P., Kinning, Kohl T., Andrysik, Zdenek, Araya, Paula, Dougherty, Hannah, Dunn, Lauren N., Ludwig, Michael, Schade, Kyndal A., Tracy, Dayna, Smith, Keith P., Granrath, Ross E., Busquet, Nicolas, Khanal, Santosh, Anderson, Ryan D., Cox, Liza L., Estrada, Belinda Enriquez, Rachubinski, Angela L., Lyford, Hannah R., Britton, Eleanor C., Fantauzzo, Katherine A., Orlicky, David J., Matsuda, Jennifer L., Song, Kunhua, Cox, Timothy C., Sullivan, Kelly D., Espinosa, Joaquin M.
Publicado 2023