Genome-wide characterisation of Foxa1 binding sites reveals several mechanisms for regulating neuronal differentiation in midbrain dopamine cells

por Metzakopian, Emmanouil, Bouhali, Kamal, Alvarez-Saavedra, Matías, Whitsett, Jeffrey A., Picketts, David J., Ang, Siew-Lan
Publicado 2015

Dopamine neuron-derived IGF-1 controls dopamine neuron firing, skill learning, and exploration

por Pristerà, Alessandro, Blomeley, Craig, Lopes, Emanuel, Threlfell, Sarah, Merlini, Elisa, Burdakov, Denis, Cragg, Stephanie, Guillemot, François, Ang, Siew-Lan
Publicado 2019

Conditional deletion of neurogenin-3 using Nkx2.1iCre results in a mouse model for the central control of feeding, activity and obesity

por Anthwal, Neal, Pelling, Michelle, Claxton, Suzanne, Mellitzer, Georg, Collin, Caitlin, Kessaris, Nicoletta, Richardson, William D., Gradwohl, Gérard, Ang, Siew-Lan
Publicado 2013

Survival of a Novel Subset of Midbrain Dopaminergic Neurons Projecting to the Lateral Septum Is Dependent on NeuroD Proteins

por Khan, Shabana, Stott, Simon R.W., Chabrat, Audrey, Truckenbrodt, Anna M., Spencer-Dene, Bradley, Nave, Klaus-Armin, Guillemot, François, Levesque, Martin, Ang, Siew-Lan
Publicado 2017

The relationship between epigenetic age and the hallmarks of aging in human cells

por Kabacik, Sylwia, Lowe, Donna, Fransen, Leonie, Leonard, Martin, Ang, Siew-Lan, Whiteman, Christopher, Corsi, Sarah, Cohen, Howard, Felton, Sarah, Bali, Radhika, Horvath, Steve, Raj, Ken
Publicado 2022

Pioneer factor ASCL1 cooperates with the mSWI/SNF complex at distal regulatory elements to regulate human neural differentiation

por Păun, Oana, Tan, Yu Xuan, Patel, Harshil, Strohbuecker, Stephanie, Ghanate, Avinash, Cobolli-Gigli, Clementina, Llorian Sopena, Miriam, Gerontogianni, Lina, Goldstone, Robert, Ang, Siew-Lan, Guillemot, François, Dias, Cristina
Publicado 2023

Transcriptional repression of Plxnc1 by Lmx1a and Lmx1b directs topographic dopaminergic circuit formation

por Chabrat, Audrey, Brisson, Guillaume, Doucet-Beaupré, Hélène, Salesse, Charleen, Schaan Profes, Marcos, Dovonou, Axelle, Akitegetse, Cléophace, Charest, Julien, Lemstra, Suzanne, Côté, Daniel, Pasterkamp, R. Jeroen, Abrudan, Monica I., Metzakopian, Emmanouil, Ang, Siew-Lan, Lévesque, Martin
Publicado 2017