Toward Quantitative Models in Safety Assessment: A Case Study to Show Impact of Dose–Response Inference on hERG Inhibition Models

por Melnikov, Fjodor, Anger, Lennart T., Hasselgren, Catrin
Publicado 2022

Generating Modeling Data From Repeat-Dose Toxicity Reports

por López-Massaguer, Oriol, Pinto-Gil, Kevin, Sanz, Ferran, Amberg, Alexander, Anger, Lennart T, Stolte, Manuela, Ravagli, Carlo, Marc, Philippe, Pastor, Manuel
Publicado 2018

Principles and procedures for handling out-of-domain and indeterminate results as part of ICH M7 recommended (Q)SAR analyses()

por Amberg, Alexander, Andaya, Roxanne V., Anger, Lennart T., Barber, Chris, Beilke, Lisa, Bercu, Joel, Bower, Dave, Brigo, Alessandro, Cammerer, Zoryanna, Cross, Kevin P., Custer, Laura, Dobo, Krista, Gerets, Helga, Gervais, Véronique, Glowienke, Susanne, Gomez, Stephen, Van Gompel, Jacky, Harvey, James, Hasselgren, Catrin, Honma, Masamitsu, Johnson, Candice, Jolly, Robert, Kemper, Raymond, Kenyon, Michelle, Kruhlak, Naomi, Leavitt, Penny, Miller, Scott, Muster, Wolfgang, Naven, Russell, Nicolette, John, Parenty, Alexis, Powley, Mark, Quigley, Donald P., Reddy, M. Vijayaraj, Sasaki, Jennifer C., Stavitskaya, Lidiya, Teasdale, Andrew, Trejo-Martin, Alejandra, Weiner, Sandy, Welch, Dennie S., White, Angela, Wichard, Joerg, Woolley, David, Myatt, Glenn J.
Publicado 2018