Wnt signaling inhibition confers induced synthetic lethality to PARP inhibitors

por Angers, Stephane
Publicado 2021

Inhibition of Tankyrases Induces Axin Stabilization and Blocks Wnt Signalling in Breast Cancer Cells

por Bao, Renyue, Christova, Tania, Song, Siyuan, Angers, Stephane, Yan, Xiaojun, Attisano, Liliana
Publicado 2012

Essential role of the Dishevelled DEP domain in a Wnt-dependent human-cell-based complementation assay

por Gammons, Melissa V., Rutherford, Trevor J., Steinhart, Zachary, Angers, Stephane, Bienz, Mariann
Publicado 2016

The F-box protein Bard (CG14317) targets the Smaug RNA-binding protein for destruction during the Drosophila maternal-to-zygotic transition

por Cao, Wen Xi, Karaiskakis, Angelo, Lin, Sichun, Angers, Stephane, Lipshitz, Howard D
Publicado 2021

Stepping stone: a cytohesin adaptor for membrane cytoskeleton restraint in the syncytial Drosophila embryo

por Liu, Jiangshu, Lee, Donghoon M., Yu, Cao Guo, Angers, Stephane, Harris, Tony J. C.
Publicado 2015

Radil controls neutrophil adhesion and motility through β2-integrin activation

por Liu, Lunhua, Aerbajinai, Wulin, Ahmed, Syed M., Rodgers, Griffin P., Angers, Stephane, Parent, Carole A.
Publicado 2012

IPO11 mediates βcatenin nuclear import in a subset of colorectal cancers

por Mis, Monika, O’Brien, Siobhan, Steinhart, Zachary, Lin, Sichun, Hart, Traver, Moffat, Jason, Angers, Stephane
Publicado 2019

Single-molecule dynamics of Dishevelled at the plasma membrane and Wnt pathway activation

por Ma, Wenzhe, Chen, Maorong, Kang, Hong, Steinhart, Zachary, Angers, Stephane, He, Xi, Kirschner, Marc W.
Publicado 2020

Identification of Novel Smoothened Ligands Using Structure-Based Docking

por Lacroix, Celine, Fish, Inbar, Torosyan, Hayarpi, Parathaman, Pranavan, Irwin, John J., Shoichet, Brian K., Angers, Stephane
Publicado 2016

A Frizzled4-LRP5 agonist promotes blood-retina barrier function by inducing a Norrin-like transcriptional response

por Zhang, Lingling, Abedin, Md., Jo, Ha-Neul, Levey, Jacklyn, Dinh, Quynh Chau, Chen, Zhe, Angers, Stephane, Junge, Harald J.
Publicado 2023

Modulation of the β-Catenin Signaling Pathway by the Dishevelled-Associated Protein Hipk1

por Louie, Sarah H., Yang, Xiao Yong, Conrad, William H., Muster, Jeanot, Angers, Stephane, Moon, Randall T., Cheyette, Benjamin N. R.
Publicado 2009

KIF14 negatively regulates Rap1a–Radil signaling during breast cancer progression

por Ahmed, Syed M., Thériault, Brigitte L., Uppalapati, Maruti, Chiu, Catherine W.N., Gallie, Brenda L., Sidhu, Sachdev S., Angers, Stéphane
Publicado 2012

nuPRISM: Microfluidic Genome-Wide Phenotypic Screening Platform for Cellular Nuclei

por Abdrabou, Abdalla M., Duong, Bill T. V., Chen, Kangfu, Atwal, Randy Singh, Labib, Mahmoud, Lin, Sichun, Angers, Stephane, Kelley, Shana O.
Publicado 2022

The Pseudomonas syringae Type III Effector HopF2 Suppresses Arabidopsis Stomatal Immunity

por Hurley, Brenden, Lee, Donghyuk, Mott, Adam, Wilton, Michael, Liu, Jun, Liu, Yulu C., Angers, Stephane, Coaker, Gitta, Guttman, David S., Desveaux, Darrell
Publicado 2014

Ca(2+)/Calmodulin-dependent protein Kinase II interacts with group I Metabotropic Glutamate and facilitates Receptor Endocytosis and ERK1/2 signaling: role of β-Amyloid

por Raka, Fitore, Di Sebastiano, Andrea R, Kulhawy, Stephanie C, Ribeiro, Fabiola M, Godin, Christina M, Caetano, Fabiana A, Angers, Stephane, Ferguson, Stephen S G
Publicado 2015

YB-1 is elevated in medulloblastoma and drives proliferation in Sonic hedgehog - dependent cerebellar granule neuron progenitor cells and medulloblastoma cells

por Dey, Abhinav, Robitaille, Mélanie, Remke, Marc, Maier, Caroline, Malhotra, Anshu, Gregorieff, Alex, Wrana, Jeffrey L, Taylor, Michael D, Angers, Stéphane, Kenney, Anna Marie
Publicado 2016

The Identification of Novel Protein-Protein Interactions in Liver that Affect Glucagon Receptor Activity

por Han, Junfeng, Zhang, Ming, Froese, Sean, Dai, Feihan F., Robitaille, Mélanie, Bhattacharjee, Alpana, Huang, Xinyi, Jia, Weiping, Angers, Stéphane, Wheeler, Michael B., Wei, Li
Publicado 2015

Identifying chemogenetic interactions from CRISPR screens with drugZ

por Colic, Medina, Wang, Gang, Zimmermann, Michal, Mascall, Keith, McLaughlin, Megan, Bertolet, Lori, Lenoir, W. Frank, Moffat, Jason, Angers, Stephane, Durocher, Daniel, Hart, Traver
Publicado 2019

Rapid On-Cell Selection of High-Performance Human Antibodies

por Philpott, David N., Gomis, Surath, Wang, Hansen, Atwal, Randy, Kelil, Abdellali, Sack, Tanja, Morningstar, Brandon, Burnie, Chris, Sargent, Edward H., Angers, Stephane, Sidhu, Sachdev, Kelley, Shana O.
Publicado 2021

Single-cell spatial transcriptomics reveals a dynamic control of metabolic zonation and liver regeneration by endothelial cell Wnt2 and Wnt9b

por Hu, Shikai, Liu, Silvia, Bian, Yu, Poddar, Minakshi, Singh, Sucha, Cao, Catherine, McGaughey, Jackson, Bell, Aaron, Blazer, Levi L., Adams, Jarret J., Sidhu, Sachdev S., Angers, Stephane, Monga, Satdarshan P.
Publicado 2022