SOX4 and SMARCA4 cooperatively regulate PI3k signaling through transcriptional activation of TGFBR2

por Mehta, Gaurav A., Angus, Steven P., Khella, Christen A., Tong, Kevin, Khanna, Pooja, Dixon, Shelley A. H., Verzi, Michael P., Johnson, Gary L., Gatza, Michael L.
Publicado 2021

Kinome and Transcriptome Profiling Reveal Broad and Distinct Activities of Erlotinib, Sunitinib, and Sorafenib in the Mouse Heart and Suggest Cardiotoxicity From Combined Signal Tr...

por Stuhlmiller, Timothy J., Zawistowski, Jon S., Chen, Xin, Sciaky, Noah, Angus, Steven P., Hicks, Sean T., Parry, Traci L., Huang, Wei, Beak, Ju Youn, Willis, Monte S., Johnson, Gary L., Jensen, Brian C.
Publicado 2017

A molecular basis for neurofibroma-associated skeletal manifestations in NF1

por Ma, Yun, Gross, Andrea, Dombi, Eva, Pemov, Alex, Choi, Kwangmin, Chaney, Katherine, Rhodes, Steven D., Angus, Steven P, Sciaky, Noah, Clapp, D Wade, Ratner, Nancy, Widemann, Brigitte C, Rios, Jonathan J, Elefteriou, Florent
Publicado 2020

Proteomic analysis defines kinase taxonomies specific for subtypes of breast cancer

por Collins, Kyla A.L., Stuhlmiller, Timothy J., Zawistowski, Jon S., East, Michael P., Pham, Trang T., Hall, Claire R., Goulet, Daniel R., Bevill, Samantha M., Angus, Steven P., Velarde, Sara H., Sciaky, Noah, Oprea, Tudor I., Graves, Lee M., Johnson, Gary L., Gomez, Shawn M.
Publicado 2018

High-content image-based analysis and proteomic profiling identifies Tau phosphorylation inhibitors in a human iPSC-derived glutamatergic neuronal model of tauopathy

por Cheng, Chialin, Reis, Surya A., Adams, Emily T., Fass, Daniel M., Angus, Steven P., Stuhlmiller, Timothy J., Richardson, Jared, Olafson, Hailey, Wang, Eric T., Patnaik, Debasis, Beauchamp, Roberta L., Feldman, Danielle A., Silva, M. Catarina, Sur, Mriganka, Johnson, Gary L., Ramesh, Vijaya, Miller, Bruce L., Temple, Sally, Kosik, Kenneth S., Dickerson, Bradford C., Haggarty, Stephen J.
Publicado 2021

FOXA1 and adaptive response determinants to HER2 targeted therapy in TBCRC 036

por Angus, Steven P., Stuhlmiller, Timothy J., Mehta, Gaurav, Bevill, Samantha M., Goulet, Daniel R., Olivares-Quintero, J. Felix, East, Michael P., Tanioka, Maki, Zawistowski, Jon S., Singh, Darshan, Sciaky, Noah, Chen, Xin, He, Xiaping, Rashid, Naim U., Chollet-Hinton, Lynn, Fan, Cheng, Soloway, Matthew G., Spears, Patricia A., Jefferys, Stuart, Parker, Joel S., Gallagher, Kristalyn K., Forero-Torres, Andres, Krop, Ian E., Thompson, Alastair M., Murthy, Rashmi, Gatza, Michael L., Perou, Charles M., Earp, H. Shelton, Carey, Lisa A., Johnson, Gary L.
Publicado 2021

Brigatinib causes tumor shrinkage in both NF2-deficient meningioma and schwannoma through inhibition of multiple tyrosine kinases but not ALK

por Chang, Long-Sheng, Oblinger, Janet L., Smith, Abbi E., Ferrer, Marc, Angus, Steven P., Hawley, Eric, Petrilli, Alejandra M., Beauchamp, Roberta L., Riecken, Lars Björn, Erdin, Serkan, Poi, Ming, Huang, Jie, Bessler, Waylan K., Zhang, Xiaohu, Guha, Rajarshi, Thomas, Craig, Burns, Sarah S., Gilbert, Thomas S. K., Jiang, Li, Li, Xiaohong, Lu, Qingbo, Yuan, Jin, He, Yongzheng, Dixon, Shelley A. H., Masters, Andrea, Jones, David R., Yates, Charles W., Haggarty, Stephen J., La Rosa, Salvatore, Welling, D. Bradley, Stemmer-Rachamimov, Anat O., Plotkin, Scott R., Gusella, James F., Guinney, Justin, Morrison, Helen, Ramesh, Vijaya, Fernandez-Valle, Cristina, Johnson, Gary L., Blakeley, Jaishri O., Clapp, D. Wade
Publicado 2021