Modulation of the monomer-dimer equilibrium and catalytic activity of SARS-CoV-2 main protease by a transition-state analog inhibitor

por Nashed, Nashaat T., Aniana, Annie, Ghirlando, Rodolfo, Chiliveri, Sai Chaitanya, Louis, John M.
Publicado 2022

Contribution of the catalytic dyad of SARS-CoV-2 main protease to binding covalent and noncovalent inhibitors

por Kovalevsky, Andrey, Aniana, Annie, Coates, Leighton, Bonnesen, Peter V., Nashed, Nashaat T., Louis, John M.
Publicado 2023

Insights into the Conformation of the Membrane Proximal Regions Critical to the Trimerization of the HIV-1 gp41 Ectodomain Bound to Dodecyl Phosphocholine Micelles

por Louis, John M., Baber, James L., Ghirlando, Rodolfo, Aniana, Annie, Bax, Ad, Roche, Julien
Publicado 2016

Insights into the mechanism of SARS-CoV-2 main protease autocatalytic maturation from model precursors

por Aniana, Annie, Nashed, Nashaat T., Ghirlando, Rodolfo, Coates, Leighton, Kneller, Daniel W., Kovalevsky, Andrey, Louis, John M.
Publicado 2023

Autoprocessing and oxyanion loop reorganization upon GC373 and nirmatrelvir binding of monomeric SARS-CoV-2 main protease catalytic domain

por Nashed, Nashaat T., Kneller, Daniel W., Coates, Leighton, Ghirlando, Rodolfo, Aniana, Annie, Kovalevsky, Andrey, Louis, John M.
Publicado 2022

Unmasking the Conformational Stability and Inhibitor Binding to SARS-CoV-2 Main Protease Active Site Mutants and Miniprecursor

por Kovalevsky, Andrey, Coates, Leighton, Kneller, Daniel W., Ghirlando, Rodolfo, Aniana, Annie, Nashed, Nashaat T., Louis, John M.
Publicado 2022

Binding of HIV-1 gp41-Directed Neutralizing and Non-Neutralizing Fragment Antibody Binding Domain (Fab) and Single Chain Variable Fragment (ScFv) Antibodies to the Ectodomain of gp...

por Louis, John M., Aniana, Annie, Lohith, Katheryn, Sayer, Jane M., Roche, Julien, Bewley, Carole A., Clore, G. Marius
Publicado 2014