Challenges and barriers to optimising sedation in intensive care: a qualitative study in eight Scottish intensive care units

por Kydonaki, Kalliopi, Hanley, Janet, Huby, Guro, Antonelli, Jean, Walsh, Timothy Simon
Publicado 2019

Challenges in the design and analysis of a factorial-design cluster randomised trial

por Stephen, Jacqueline, Lee, Robert, Kydonaki, Kalliopi, Antonelli, Jean, Walsh, Timothy S, Weir, Christopher J
Publicado 2015

Rationale, design and methodology of a trial evaluating three strategies designed to improve sedation quality in intensive care units (DESIST study)

por Walsh, Timothy S, Kydonaki, Kalliopi, Antonelli, Jean, Stephen, Jacqueline, Lee, Robert J, Everingham, Kirsty, Hanley, Janet, Uutelo, Kimmo, Peltola, Petra, Weir, Christopher J
Publicado 2016

Evaluation of new or repurposed treatments for COVID-19: protocol for the phase Ib/IIa DEFINE trial platform

por Gaughan, Erin, Quinn, Tom, Bruce, Annya, Antonelli, Jean, Young, Vikki, Mair, Joanne, Akram, Ahsan, Hirani, Nik, Koch, Oliver, Mackintosh, Claire, Norrie, John, Dear, James W, Dhaliwal, Kevin
Publicado 2021

Phase 2 randomised placebo-controlled trial of spironolactone and dexamethasone versus dexamethasone in COVID-19 hospitalised patients in Delhi

por Wadhwa, Bharti, Malhotra, Vikas, Kerai, Sukhyanti, Husain, Farah, Pandey, Nalini Bala, Saxena, Kirti N., Singh, Vinay, Quinn, Tom M., Li, Feng, Gaughan, Erin, Shankar-Hari, Manu, Mills, Bethany, Antonelli, Jean, Bruce, Annya, Finlayson, Keith, Moore, Anne, Dhaliwal, Kevin, Edwards, Christopher
Publicado 2023

Predictive value of cell-surface markers in infections in critically ill patients: protocol for an observational study (ImmuNe FailurE in Critical Therapy (INFECT) Study)

por Conway Morris, Andrew, Datta, Deepankar, Shankar-Hari, Manu, Weir, Christopher J, Rennie, Jillian, Antonelli, Jean, Rossi, Adriano G, Warner, Noel, Keenan, Jim, Wang, Alice, Brown, K Alun, Lewis, Sion, Mare, Tracey, Simpson, A John, Hulme, Gillian, Dimmick, Ian, Walsh, Timothy S
Publicado 2016

Early PREdiction of Severe Sepsis (ExPRES-Sepsis) study: protocol for an observational derivation study to discover potential leucocyte cell surface biomarkers

por Datta, Deepankar, Conway Morris, Andrew, Antonelli, Jean, Warner, Noel, Brown, Kenneth Alun, Wright, John, Simpson, A John, Rennie, Jillian, Hulme, Gillian, Lewis, Sion Marc, Mare, Tracey Anne, Cookson, Sharon, Weir, Christopher John, Dimmick, Ian, Keenan, Jim, Rossi, Adriano Giorgio, Shankar-Hari, Manu, Walsh, Timothy S
Publicado 2016

Cell-surface signatures of immune dysfunction risk-stratify critically ill patients: INFECT study

por Conway Morris, Andrew, Datta, Deepankar, Shankar-Hari, Manu, Stephen, Jacqueline, Weir, Christopher J., Rennie, Jillian, Antonelli, Jean, Bateman, Anthony, Warner, Noel, Judge, Kevin, Keenan, Jim, Wang, Alice, Burpee, Tony, Brown, K. Alun, Lewis, Sion M., Mare, Tracey, Roy, Alistair I., Hulme, Gillian, Dimmick, Ian, Rossi, Adriano G., Simpson, A. John, Walsh, Timothy S.
Publicado 2018

An Inhaled Galectin-3 Inhibitor in COVID-19 Pneumonitis: A Phase Ib/IIa Randomized Controlled Clinical Trial (DEFINE)

por Gaughan, Erin E., Quinn, Tom M., Mills, Andrew, Bruce, Annya M., Antonelli, Jean, MacKinnon, Alison C., Aslanis, Vassilios, Li, Feng, O’Connor, Richard, Boz, Cecilia, Mills, Ross, Emanuel, Philip, Burgess, Matthew, Rinaldi, Giulia, Valanciute, Asta, Mills, Bethany, Scholefield, Emma, Hardisty, Gareth, Findlay, Emily Gwyer, Parker, Richard A., Norrie, John, Dear, James W., Akram, Ahsan R., Koch, Oliver, Templeton, Kate, Dockrell, David H., Walsh, Timothy S., Partridge, Stephen, Humphries, Duncan, Wang-Jairaj, Jie, Slack, Robert J., Schambye, Hans, Phung, De, Gravelle, Lise, Lindmark, Bertil, Shankar-Hari, Manu, Hirani, Nikhil, Sethi, Tariq, Dhaliwal, Kevin
Publicado 2022

Randomised controlled trial of intravenous nafamostat mesylate in COVID pneumonitis: Phase 1b/2a experimental study to investigate safety, Pharmacokinetics and Pharmacodynamics

por Quinn, Tom M., Gaughan, Erin E., Bruce, Annya, Antonelli, Jean, O'Connor, Richard, Li, Feng, McNamara, Sarah, Koch, Oliver, MacKintosh, Claire, Dockrell, David, Walsh, Timothy, Blyth, Kevin G., Church, Colin, Schwarze, Jürgen, Boz, Cecilia, Valanciute, Asta, Burgess, Matthew, Emanuel, Philip, Mills, Bethany, Rinaldi, Giulia, Hardisty, Gareth, Mills, Ross, Findlay, Emily Gwyer, Jabbal, Sunny, Duncan, Andrew, Plant, Sinéad, Marshall, Adam D.L., Young, Irene, Russell, Kay, Scholefield, Emma, Nimmo, Alastair F., Nazarov, Islom B., Churchill, Grant C., McCullagh, James S.O., Ebrahimi, Kourosh H., Ferrett, Colin, Templeton, Kate, Rannard, Steve, Owen, Andrew, Moore, Anne, Finlayson, Keith, Shankar-Hari, Manu, Norrie, John, Parker, Richard A., Akram, Ahsan R., Anthony, Daniel C., Dear, James W., Hirani, Nik, Dhaliwal, Kevin
Publicado 2022