Tumor Immunology and Immune Checkpoint Inhibitors in Non-Small Cell Lung Cancer

por Jung, Chi Young, Antonia, Scott J.
Publicado 2018

A new role for NFκB in immunosurveillance and its implications for cancer immunotherapy

por Beg, Amer A, Khan, Tahira, Antonia, Scott J
Publicado 2013

A GM-CSF and CD40L bystander vaccine is effective in a murine breast cancer model

por Soliman, Hatem, Mediavilla-Varela, Melanie, Antonia, Scott J
Publicado 2015

The anti-fibrotic agent pirfenidone synergizes with cisplatin in killing tumor cells and cancer-associated fibroblasts

por Mediavilla-Varela, Melanie, Boateng, Kingsley, Noyes, David, Antonia, Scott J.
Publicado 2016

Clinical associations of mucin 1 in human lung cancer and precancerous lesions

por Saltos, Andreas, Khalil, Farah, Smith, Michelle, Li, Jiannong, Schell, Michael, Antonia, Scott J., Gray, Jhanelle E.
Publicado 2018

A Novel Antagonist of the Immune Checkpoint Protein Adenosine A2a Receptor Restores Tumor-Infiltrating Lymphocyte Activity in the Context of the Tumor Microenvironment

por Mediavilla-Varela, Melanie, Castro, Julio, Chiappori, Alberto, Noyes, David, Hernandez, Dalia C., Allard, Bertrand, Stagg, John, Antonia, Scott J.
Publicado 2017

Progressive hypoventilation due to mixed CD8(+) and CD4(+) lymphocytic polymyositis following tremelimumab - durvalumab treatment

por John, Sooraj, Antonia, Scott J., Rose, Trevor A., Seifert, Robert P., Centeno, Barbara A., Wagner, Aaron S., Creelan, Ben C.
Publicado 2017

Strategies for power calculations in predictive biomarker studies in survival data

por Chen, Dung-Tsa, Huang, Po-Yu, Lin, Hui-Yi, Haura, Eric B., Antonia, Scott J., Cress, W. Douglas, Gray, Jhanelle E.
Publicado 2016

Phase 1 trial of dasatinib combined with afatinib for epidermal growth factor receptor- (EGFR-) mutated lung cancer with acquired tyrosine kinase inhibitor (TKI) resistance

por Creelan, Ben C., Gray, Jhanelle E., Tanvetyanon, Tawee, Chiappori, Alberto A., Yoshida, Takeshi, Schell, Michael J., Antonia, Scott J., Haura, Eric B.
Publicado 2019

Clinical Trials with Biologic Primary Endpoints in Immuno-oncology: Concepts and Usage

por Isaacs, James, Tan, Aaron C., Hanks, Brent A., Wang, Xiaofei, Owzar, Kouros, Herndon, James E., Antonia, Scott J., Piantadosi, Steven, Khasraw, Mustafa
Publicado 2022

Characterizing the Shifting Real-World Treatment Landscape by PD-L1 Testing Status and Expression Level in Advanced Non-Small Cell Lung Cancer

por Ge, Wenzhen, Wu, Ning, Quek, Ruben G. W., Liu, Jinjie, Pouliot, Jean-Francois, Dietz, Hilary, Jalbert, Jessica J., Harnett, James, Antonia, Scott J.
Publicado 2022

A Bayesian pick-the-winner design in a randomized phase II clinical trial

por Chen, Dung-Tsa, Huang, Po-Yu, Lin, Hui-Yi, Chiappori, Alberto A., Gabrilovich, Dmitry I., Haura, Eric B., Antonia, Scott J., Gray, Jhanelle E.
Publicado 2017

The Current Understanding of the Endocrine Effects From Immune Checkpoint Inhibitors and Recommendations for Management

por Girotra, Monica, Hansen, Aaron, Farooki, Azeez, Byun, David J, Min, Le, Creelan, Ben C, Callahan, Margaret K, Atkins, Michael B, Sharon, Elad, Antonia, Scott J, West, Pamela, Gravell, Amy E
Publicado 2018

A Phase 2 Clinical Trial of Combination Nivolumab, Ipilimumab, and Paclitaxel in Patients With Untreated Metastatic NSCLC: The OPTIMAL Trial

por Clarke, Jeffrey M., Gu, Lin, Wang, Xiaofei F., Stinchcombe, Thomas E., Stevenson, Marvaretta M., Ramalingam, Sundhar, Shariff, Afreen, Garst, Jennifer, Nixon, Andrew B., Antonia, Scott J., Crawford, Jeffrey, Ready, Neal E.
Publicado 2022

Randomized-controlled phase II trial of salvage chemotherapy after immunization with a TP53-transfected dendritic cell-based vaccine (Ad.p53-DC) in patients with recurrent small ce...

por Chiappori, Alberto A., Williams, Charles C., Gray, Jhanelle E., Tanvetyanon, Tawee, Haura, Eric B., Creelan, Ben C., Thapa, Ram, Chen, Dung-Tsa, Simon, George R., Bepler, Gerold, Gabrilovich, Dmitry I., Antonia, Scott J.
Publicado 2018

Long-Term Clinical Responses of Neoadjuvant Dendritic Cell Infusions and Radiation in Soft Tissue Sarcoma

por Raj, Shailaja, Bui, Marilyn M., Springett, Gregory, Conley, Anthony, Lavilla-Alonso, Sergio, Zhao, Xiuhua, Chen, Dungsa, Haysek, Randy, Gonzalez, Ricardo, Letson, G. Douglas, Finkelstein, Steven Eric, Chiappori, Alberto A., Gabrilovitch, Dmitry I., Antonia, Scott J.
Publicado 2015

Third-Line Nivolumab Monotherapy in Recurrent SCLC: CheckMate 032

por Ready, Neal, Farago, Anna F., de Braud, Filippo, Atmaca, Akin, Hellmann, Matthew D., Schneider, Jeffrey G., Spigel, David R., Moreno, Victor, Chau, Ian, Hann, Christine L., Eder, Joseph Paul, Steele, Nicola L., Pieters, Anne, Fairchild, Justin, Antonia, Scott J.
Publicado 2018

A phase I study of indoximod in patients with advanced malignancies

por Soliman, Hatem H., Minton, Susan E., Han, Hyo Sook, Ismail-Khan, Roohi, Neuger, Anthony, Khambati, Fatema, Noyes, David, Lush, Richard, Chiappori, Alberto A., Roberts, John D., Link, Charles, Vahanian, Nicholas N., Mautino, Mario, Streicher, Howard, Sullivan, Daniel M., Antonia, Scott J.
Publicado 2016

Safety, pharmacokinetics, and pharmacodynamics of oral omaveloxolone (RTA 408), a synthetic triterpenoid, in a first-in-human trial of patients with advanced solid tumors

por Creelan, Ben C, Gabrilovich, Dmitry I, Gray, Jhanelle E, Williams, Charles C, Tanvetyanon, Tawee, Haura, Eric B, Weber, Jeffrey S, Gibney, Geoffrey T, Markowitz, Joseph, Proksch, Joel W, Reisman, Scott A, McKee, Mark D, Chin, Melanie P, Meyer, Colin J, Antonia, Scott J
Publicado 2017

A phase I/randomized phase II study of GM.CD40L vaccine in combination with CCL21 in patients with advanced lung adenocarcinoma

por Gray, Jhanelle E., Chiappori, Alberto, Williams, Charlie C., Tanvetyanon, Tawee, Haura, Eric B., Creelan, Ben C., Kim, Jongphil, Boyle, Theresa A., Pinder-Schenck, Mary, Khalil, Farah, Altiok, Soner, Devane, Rebecca, Noyes, David, Mediavilla-Varela, Melanie, Smilee, Renee, Hopewell, Emily L., Kelley, Linda, Antonia, Scott J.
Publicado 2018