Special Issue “Adductomics: Elucidating the Environmental Causes of Disease”

por Pereira, Sofia A., Antunes, Alexandra M. M.
Publicado 2019

Metabolic Profile of Four Selected Cathinones in Microsome Incubations: Identification of Phase I and II Metabolites by Liquid Chromatography High Resolution Mass Spectrometry

por Lopes, Beatriz T., Caldeira, Maria João, Gaspar, Helena, Antunes, Alexandra M. M.
Publicado 2021

2'-Deoxythymidine Adducts from the Anti-HIV Drug Nevirapine

por Antunes, Alexandra M. M., Wolf, Benjamin, Oliveira, M. Conceição, Beland, Frederick A., Marques, M. Matilde
Publicado 2013

Severe Acute Kidney Injury and Double Tubulopathy Due to Dual Toxicity Caused by Combination Antiretroviral Therapy

por Soto, Karina, Campos, Pedro, Manso, Rita, Antunes, Alexandra M.M., Morello, Judit, Perazella, Mark A.
Publicado 2018

Mass Spectrometry-Based Methodologies for Targeted and Untargeted Identification of Protein Covalent Adducts (Adductomics): Current Status and Challenges

por Nunes, João, Charneira, Catarina, Morello, Judit, Rodrigues, João, Pereira, Sofia A., Antunes, Alexandra M. M.
Publicado 2019

A simple method to measure sulfonation in man using paracetamol as probe drug

por Marto, Natália, Morello, Judit, Antunes, Alexandra M. M., Azeredo, Sofia, Monteiro, Emília C., Pereira, Sofia A.
Publicado 2021

Synthesis and Biological Activity of 6-Selenocaffeine: Potential Modulator of Chemotherapeutic Drugs in Breast Cancer Cells

por Martins, Inês L., Miranda, Joana P., Oliveira, Nuno G., Fernandes, Ana S., Gonçalves, Sandrina, Antunes, Alexandra M. M.
Publicado 2013

A Metabolomics-Inspired Strategy for the Identification of Protein Covalent Modifications

por Nunes, João, Charneira, Catarina, Nunes, Carolina, Gouveia-Fernandes, Sofia, Serpa, Jacinta, Morello, Judit, Antunes, Alexandra M. M.
Publicado 2019

Tryptophanol-Derived Oxazolopyrrolidone Lactams as Potential Anticancer Agents against Gastric Adenocarcinoma

por Espadinha, Margarida, Barcherini, Valentina, Gonçalves, Lídia M., Molins, Elies, Antunes, Alexandra M. M., Santos, Maria M. M.
Publicado 2021

Metabolic stability and metabolite profiling of emerging synthetic cathinones

por Lopes, Rita P., Ferro, Raquel A., Milhazes, Margarida, Figueira, Margarida, Caldeira, Maria João, Antunes, Alexandra M. M., Gaspar, Helena
Publicado 2023

New Ruthenium-Cyclopentadienyl Complexes Affect Colorectal Cancer Hallmarks Showing High Therapeutic Potential

por Brás, Ana Rita, Fernandes, Pedro, Moreira, Tiago, Morales-Sanfrutos, Julia, Sabidó, Eduard, Antunes, Alexandra M. M., Valente, Andreia, Preto, Ana
Publicado 2023

First Chemical Profile Analysis of Acacia Pods

por Pedro, Soraia I., Fernandes, Tiago A., Luís, Ângelo, Antunes, Alexandra M. M., Gonçalves, José C., Gominho, Jorge, Gallardo, Eugenia, Anjos, Ofélia
Publicado 2023

Metabolism-Guided Optimization of Tryptophanol-Derived Isoindolinone p53 Activators

por Barcherini, Valentina, Loureiro, Joana B., Sena, Ana, Madeira, Catarina, Leandro, Paula, Saraiva, Lucília, Antunes, Alexandra M. M., Santos, Maria M. M.
Publicado 2023

The Mercapturomic Profile of Health and Non-Communicable Diseases

por Gonçalves-Dias, Clara, Morello, Judit, Semedo, Valdir, Correia, M. João, Coelho, Nuno R., Monteiro, Emilia C., Antunes, Alexandra M. M., Pereira, Sofia A.
Publicado 2019

Human Cystathionine γ-Lyase Is Inhibited by s-Nitrosation: A New Crosstalk Mechanism between NO and H(2)S

por Fernandes, Dalila G. F., Nunes, João, Tomé, Catarina S., Zuhra, Karim, Costa, João M. F., Antunes, Alexandra M. M., Giuffrè, Alessandro, Vicente, João B.
Publicado 2021

Covalent Histone Modification by an Electrophilic Derivative of the Anti-HIV Drug Nevirapine

por Harjivan, Shrika G., Charneira, Catarina, Martins, Inês L., Pereira, Sofia A., Espadas, Guadalupe, Sabidó, Eduard, Beland, Frederick A., Marques, M. Matilde, Antunes, Alexandra M. M.
Publicado 2021

Oxidation of 2-Hydroxynevirapine, a Phenolic Metabolite of the Anti-HIV Drug Nevirapine: Evidence for an Unusual Pyridine Ring Contraction

por Antunes, Alexandra M. M., Sidarus, Muna, Novais, David A., Harjivan, Shrika G., Santos, Pedro P., da Silva, João L. Ferreira, Beland, Frederick A., Marques, M. Matilde
Publicado 2012

Nevirapine Biotransformation Insights: An Integrated In Vitro Approach Unveils the Biocompetence and Glutathiolomic Profile of a Human Hepatocyte-Like Cell 3D Model

por Cipriano, Madalena, Pinheiro, Pedro F, Sequeira, Catarina O, Rodrigues, Joana S, Oliveira, Nuno G, Antunes, Alexandra M M, Castro, Matilde, Marques, M Matilde, Pereira, Sofia A, Miranda, Joana P
Publicado 2020

Cysteine as a Multifaceted Player in Kidney, the Cysteine-Related Thiolome and Its Implications for Precision Medicine

por Correia, Maria João, Pimpão, António B., Fernandes, Dalila G. F., Morello, Judit, Sequeira, Catarina O., Calado, Joaquim, Antunes, Alexandra M. M., Almeida, Manuel S., Branco, Patrícia, Monteiro, Emília C., Vicente, João B., Serpa, Jacinta, Pereira, Sofia A.
Publicado 2022

Synthetic Red Blood Cell-Specific Glycolytic Intermediate 2,3-Diphosphoglycerate (2,3-DPG) Inhibits Plasmodium falciparum Development In Vitro

por Morais, Inês, Medeiros, Márcia M., Carvalho, Maria, Morello, Judit, Teixeira, Sara M., Maciel, Suelma, Nhantumbo, Janice, Balau, Ana, Rosa, Margarida T. G., Nogueira, Fátima, Rodrigues, João Alexandre, Carvalho, Filomena A., Antunes, Alexandra M. M., Arez, Ana Paula
Publicado 2022