A comparative study on the efficacies of gonadotropin-releasing hormone (GnRH) agonist and GnRH antagonist in neoadjuvant androgen deprivation therapy combined with transperineal p...

por Miki, Kenta, Sasaki, Hiroshi, Kido, Masahito, Takahashi, Hiroyuki, Aoki, Manabu, Egawa, Shin
Publicado 2016

Mechanism of Darunavir (DRV)’s High Genetic Barrier to HIV-1 Resistance: A Key V32I Substitution in Protease Rarely Occurs, but Once It Occurs, It Predisposes HIV-1 To Develop DRV...

por Aoki, Manabu, Das, Debananda, Hayashi, Hironori, Aoki-Ogata, Hiromi, Takamatsu, Yuki, Ghosh, Arun K., Mitsuya, Hiroaki
Publicado 2018

Predictive factors for disease progression after salvage radiation therapy in biochemical recurrent patients treated by radical prostatectomy

por Aikawa, Koichi, Kimura, Shoji, Urabe, Fumihiko, Iwatani, Kosuke, Tashiro, Kojiro, Ochi, Atsuhiko, Abe, Hirokazu, Aoki, Manabu, Kimura, Takahiro
Publicado 2023

Analysis of prognostic factors in localized high-risk prostate cancer patients treated with HDR brachytherapy, hypofractionated 3D-CRT and neoadjuvant/adjuvant androgen deprivation...

por Aoki, Manabu, Miki, Kenta, Kido, Masahito, Sasaki, Hiroshi, Nakamura, Wataru, Kijima, Yoshikazu, Kobayashi, Masao, Egawa, Shin, Kanehira, Chihiro
Publicado 2014

Pulmonary Metastases After Low-Dose-Rate Brachytherapy for Localized Prostate Cancer

por Kido, Masahito, Kuruma, Hidetoshi, Sasaki, Hiroshi, Miki, Kenta, Aoki, Manabu, Kimura, Takahiro, Takahash, Hiroyuki, Kanehira, Chihiro, Egawa, Shin
Publicado 2014

Do androgen deprivation and the biologically equivalent dose matter in low‐dose‐rate brachytherapy for intermediate‐risk prostate cancer?

por Tabata, Ryuji, Kimura, Takahiro, Kuruma, Hidetoshi, Sasaki, Hiroshi, Kido, Masahito, Miki, Kenta, Takahashi, Hiroyuki, Aoki, Manabu, Egawa, Shin
Publicado 2016

Current status and outcomes of patients developing PSA recurrence after prostatectomy who were treated with salvage radiotherapy: a JROSG surveillance study

por Mizowaki, Takashi, Aoki, Manabu, Nakamura, Katsumasa, Yorozu, Atsunori, Kokubo, Masaki, Karasawa, Katsuyuki, Kozuka, Takuyo, Nakajima, Nobuaki, Sasai, Keisuke, Akimoto, Tetsuo
Publicado 2015

Human Neutrophil Elastase Induce Interleukin-10 Expression in Peripheral Blood Mononuclear Cells through Protein Kinase C Theta/Delta and Phospholipase Pathways

por Kawata, Jin, Yamaguchi, Rui, Yamamoto, Takatoshi, Ishimaru, Yasuji, Sakamoto, Arisa, Aoki, Manabu, Kitano, Masafumi, Umehashi, Misako, Hirose, Eiji, Yamaguchi, Yasuo
Publicado 2016

Transperineal prostate brachytherapy, using I-125 seed with or without adjuvant androgen deprivation, in patients with intermediate-risk prostate cancer: study protocol for a phase...

por Miki, Kenta, Kiba, Takayoshi, Sasaki, Hiroshi, Kido, Masahito, Aoki, Manabu, Takahashi, Hiroyuki, Miyakoda, Keiko, Dokiya, Takushi, Yamanaka, Hidetoshi, Fukushima, Masanori, Egawa, Shin
Publicado 2010

Adjuvant radiotherapy after prostatectomy for prostate cancer in Japan: a multi-institutional survey study of the JROSG

por Aoki, Manabu, Mizowaki, Takashi, Akimoto, Tetsuo, Nakamura, Katsumasa, Ejima, Yasuo, Jingu, Keiichi, Tamai, Yoshifumi, Nakajima, Nobuaki, Takemoto, Shinya, Kokubo, Masaki, Katoh, Hiroyuki
Publicado 2014

The identification of ᴅ-tryptophan as a bioactive substance for postembryonic ovarian development in the planarian Dugesia ryukyuensis

por Kobayashi, Kazuya, Maezawa, Takanobu, Tanaka, Hiroyuki, Onuki, Hiroyuki, Horiguchi, Yurie, Hirota, Hiroshi, Ishida, Tetsuo, Horiike, Kihachiro, Agata, Yasutoshi, Aoki, Manabu, Hoshi, Motonori, Matsumoto, Midori
Publicado 2017

Single atom changes in newly synthesized HIV protease inhibitors reveal structural basis for extreme affinity, high genetic barrier, and adaptation to the HIV protease plasticity

por Bulut, Haydar, Hattori, Shin-ichiro, Aoki-Ogata, Hiromi, Hayashi, Hironori, Das, Debananda, Aoki, Manabu, Davis, David A., Rao, Kalapala Venkateswara, Nyalapatla, Prasanth R., Ghosh, Arun K., Mitsuya, Hiroaki
Publicado 2020

Trimodal therapy with high-dose-rate brachytherapy and hypofractionated external beam radiation combined with long-term androgen deprivation for unfavorable-risk prostate cancer

por Mori, Keiichiro, Sasaki, Hiroshi, Tsutsumi, Yuki, Sato, Shun, Takiguchi, Yuki, Saito, Shun, Nishi, Eriko, Ishii, Gen, Yamamoto, Toshihiro, Koike, Yusuke, Miki, Jun, Shimomura, Tatsuya, Kimura, Takahiro, Miki, Kenta, Shariat, Shahrokh F., Takahashi, Hiroyuki, Aoki, Manabu, Egawa, Shin
Publicado 2021

GRL-142 binds to and impairs HIV-1 integrase nuclear localization signal and potently suppresses highly INSTI-resistant HIV-1 variants

por Aoki, Manabu, Aoki-Ogata, Hiromi, Bulut, Haydar, Hayashi, Hironori, Takamune, Nobutoki, Kishimoto, Naoki, Tanaka, Hiroki, Higashi-Kuwata, Nobuyo, Hattori, Shin-ichiro, Das, Debananda, Venkateswara Rao, Kalapala, Iwama, Kazuya, Davis, David A., Hasegawa, Kazuya, Murayama, Kazutaka, Yarchoan, Robert, Ghosh, Arun K., Pau, Alice K., Machida, Shinichi, Misumi, Shogo, Mitsuya, Hiroaki
Publicado 2023

A novel central nervous system-penetrating protease inhibitor overcomes human immunodeficiency virus 1 resistance with unprecedented aM to pM potency

por Aoki, Manabu, Hayashi, Hironori, Rao, Kalapala Venkateswara, Das, Debananda, Higashi-Kuwata, Nobuyo, Bulut, Haydar, Aoki-Ogata, Hiromi, Takamatsu, Yuki, Yedidi, Ravikiran S, Davis, David A, Hattori, Shin-ichiro, Nishida, Noriko, Hasegawa, Kazuya, Takamune, Nobutoki, Nyalapatla, Prasanth R, Osswald, Heather L, Jono, Hirofumi, Saito, Hideyuki, Yarchoan, Robert, Misumi, Shogo, Ghosh, Arun K, Mitsuya, Hiroaki
Publicado 2017

Multi-institutional retrospective analysis of learning curves on dosimetry and operation time before and after introduction of intraoperatively built custom-linked seeds in prostat...

por Ishiyama, Hiromichi, Satoh, Takefumi, Yorozu, Atsunori, Saito, Shiro, Kataoka, Masaaki, Hashine, Katsuyoshi, Nakamura, Ryuji, Tanji, Susumu, Masui, Koji, Okihara, Koji, Ohashi, Toshio, Momma, Tetsuo, Aoki, Manabu, Miki, Kenta, Kato, Masako, Morita, Masashi, Katayama, Norihisa, Nasu, Yasutomo, Kawanaka, Takashi, Fukumori, Tomoharu, Ito, Fumitaka, Shiroki, Ryoichi, Baba, Yuji, Inadome, Akito, Yoshioka, Yasuo, Takayama, Hitoshi, Hayakawa, Kazushige
Publicado 2016

Identification of SARS-CoV-2 M(pro) inhibitors containing P1’ 4-fluorobenzothiazole moiety highly active against SARS-CoV-2

por Higashi-Kuwata, Nobuyo, Tsuji, Kohei, Hayashi, Hironori, Bulut, Haydar, Kiso, Maki, Imai, Masaki, Ogata-Aoki, Hiromi, Ishii, Takahiro, Kobayakawa, Takuya, Nakano, Kenta, Takamune, Nobutoki, Kishimoto, Naoki, Hattori, Shin-ichiro, Das, Debananda, Uemura, Yukari, Shimizu, Yosuke, Aoki, Manabu, Hasegawa, Kazuya, Suzuki, Satoshi, Nishiyama, Akie, Saruwatari, Junji, Shimizu, Yukiko, Sukenaga, Yoshikazu, Takamatsu, Yuki, Tsuchiya, Kiyoto, Maeda, Kenji, Yoshimura, Kazuhisa, Iida, Shun, Ozono, Seiya, Suzuki, Tadaki, Okamura, Tadashi, Misumi, Shogo, Kawaoka, Yoshihiro, Tamamura, Hirokazu, Mitsuya, Hiroaki
Publicado 2023